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Divergent Delivery and Expression Kinetics of Lipid and Polymeric Nanoparticles across mRNA Modalities
Authors: Irafasha C Casmil, Josh J Friesen, Nuthan V Bathula, Anneke Strumpel, Chia Hao Ho, Ilana Guez, Kristen Y S Kong, Andrew J Varley, Shigeki J Miyake-Stoner, Parinaz Aliahmad, Nathaniel S Wang, Andrew J Geall, Anna K Blakney
Journal: Advanced Science
PubMed ID: 40650657
Doi: 10.1002/advs.202508907
Products & Services: Circular RNA synthesis   
Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates
Authors: Nita Patel, Asma Rehman, Jessica F Trost, Rhonda Flores, Zach Longacre, Mimi Guebre-Xabier, Haixia Zhou, Bin Zhou, Kelsey Jacobson, Desheng Jiang, Xiaoyun Bai, Rafia Khatoon, Thomas Kort, James Norton, M Madhangi, Melinda Hersey, Ann M Greene, Filip Dubovsky, Gale Smith
Journal: Nature Communications
PubMed ID: 40681543
Doi: 10.1038/s41467-025-61964-y
Products & Services: Gene Synthesis   
Potentiating the Efficacy of mRNA Vaccines through NIR-II Imaging-Guided Precise Vaccination
Authors: Mengfei Li, Xue Zheng, Xinyang Yu, Shaolong Qi, Shoujun Zhu, Guocan Yu, Songling Zhang
Journal: Advanced Science
PubMed ID: 40681479
Doi: 10.1002/advs.202413014
Products & Services: Peptide Synthesis   
API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs
Authors: Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou
Journal: Advanced Science
PubMed ID: 40641422
Doi: 10.1002/advs.202505479
Products & Services: Protein and Antibody Isolation   
Regulation of inflammatory responses by pH-dependent transcriptional condensates
Authors: Zhongyang Wu, Scott D Pope, Nasiha S Ahmed, Diana L Leung, Yu Hong, Stephanie Hajjar, Cathleen Krabak, Zhe Zhong, Krishnan Raghunathan, Qiuyu Yue, Diya M Anand, Elizabeth B Kopp, Daniel Okin, Weiyi Ma, Ivan Zanoni, Jonathan C Kagan, Jay R Thiagarajah, Diana C Hargreaves, Ruslan Medzhitov, Xu Zhou
Journal: Cell
PubMed ID: 40680734
Doi: 10.1016/j.cell.2025.06.033
Products & Services: Gene Synthesis   
Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition
Authors: Yiru Wang, Lixia Zhao, Yi Zhang, Xiuxia Gao, Yannan Wang, Wenping Shi, Roger D Kornberg, Heqiao Zhang
Journal: Cell
PubMed ID: 40628260
Doi: 10.1016/j.cell.2025.06.017
Products & Services: Codon Optimization   
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics
Authors: M Alejandra Tortorici, Annette Choi, Cecily A Gibson, Jimin Lee, Jack T Brown, Cameron Stewart, Anshu Joshi, Sheri Harari, Isabelle Willoughby, Catherine Treichel, Elizabeth M Leaf, Jesse D Bloom, Neil P King, Christine Tait-Burkard, Gary R Whittaker, David Veesler
Journal: Nature
PubMed ID: 40634609
Doi: 10.1038/s41586-025-09155-z
Products & Services: Gene Synthesis   
Single-cell RNA sequencing and PANDORA-seq reveal the pivotal role of piRNA in heat stress-induced testicular injury
Authors: Mailin Gan, Jianfeng Ma, Yuhang Lei, Yiting Yang, Yuheng Pan, Shuang Wu, Siyu Chen, Jiaxin Li, Linyuan Shen, Li Zhu
Journal: International Journal of Biological Macromolecules
PubMed ID: 40609925
Doi: 10.1016/j.ijbiomac.2025.145674
Products & Services: Protein and Antibody Isolation   
A novel and sensitive AuNPs/tetracystein-glucose dehydrogenase(GDH)/ screen-printed electrode(SPE)-based electrochemical glucose biosensor
Authors: Ting Zhang , Danni Ma , Fuman Cai
Journal: Microchemical Journal
Doi: doi.org/10.1016/j.microc.2025.114629
Products & Services: Codon Optimization   Gene Synthesis   Molecular Biology Reagents   
Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation
Authors: Rajamanikkam Kamaraj, Ivana Mejdrová, Maria Krutakova, Tomas Smutny, Kryštof Škach, Klara Dohnalova, Lucie Smutna, Dharani Sai Sreekanth Nellore, Jan Dusek, Karel Chalupsky, Jana Hricová, Thales Kronenberger, Aaron Stahl, Markus Templin, Albert Braeuning, Radim Nencka, Petr Pavek
Journal: Journal of Medicinal Chemistry
PubMed ID: 40650588
Doi: 10.1021/acs.jmedchem.4c03134
Products & Services: Custom Vector Construction   
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