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Hepatic neddylation deficiency triggers fatal liver injury via inducing NF-κB-inducing kinase in mice

Authors: Cheng Xu , Hongyi Zhou , Yulan Jin , Khushboo Sahay , Anna Robicsek , Yisong Liu , Kunzhe Dong , Jiliang Zhou , Amanda Barrett , Huabo Su , Weiqin Chen

Journal: Nat Commun

PubMed ID: 36526632

Doi: 10.1038/s41467-022-35525-6

Products & Services: Synthetic sgRNA and crRNA Service Plasmid DNA Preparation

Human Dectin-1 is -glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

Authors: Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, Gordon D Brown, Masamichi Nagae, Sho Yamasaki

Journal: Elife

PubMed ID: 36479973

Doi: 10.7554/eLife.83037

Products & Services: Synthetic sgRNA and crRNA Service

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Authors: Liang Chen, Biyun Zhu, Gaomeng Ru, Haowei Meng, Yongchang Yan, Mengjia Hong, Dan Zhang, Changming Luan, Shun Zhang, Hao Wu, Hongyi Gao, Sijia Bai, Changqing Li, Ruoyi Ding, Niannian Xue, Zhixin Lei, Yuting Chen, Yuting Guan, Stefan Siwko, Yiyun Cheng, Gaojie Song, Liren Wang, Chengqi Yi, Mingyao Liu, Dali Li

Journal: Nat Biotechnol

PubMed ID: 36357717

Doi: 10.1038/s41587-022-01532-7

Products & Services: Synthetic sgRNA and crRNA Service

Available online 28 June 2022 0925-4005/© 2022 Elsevier B.V. All rights reserved. A universal CRISPR/Cas12a-mediated AuNPs aggregation-based surface-enhanced Raman scattering (CRISPR/Cas-SERS) platform for virus gene detection

Authors: Ailing Su ， Yuan Liu , Xiumian Cao , Weiqing Xu , Chongyang Liang , Shuping Xu

Journal: Sensors and Actuators B: Chemical

Doi: 10.1016/j.snb.2022.132295

Products & Services: Synthetic sgRNA and crRNA Service

A new family of CRISPR-type V nucleases with C-rich PAM recognition

Authors: Tomas Urbaitis, Giedrius Gasiunas, Joshua K Young, Zhenglin Hou, Sushmitha Paulraj, Egle Godliauskaite, Mantvyda M Juskeviciene, Migle Stitilyte, Monika Jasnauskaite, Megumu Mabuchi, G Brett Robb, Virginijus Siksnys

Journal: EMBO Rep

PubMed ID: 36268581

Doi: 10.15252/embr.202255481

Products & Services: Synthetic sgRNA and crRNA Service

Non-viral，specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

Authors: Jiqin Zhang , Yongxian Hu , Jiaxuan Yang , Wei Li , Mingming Zhang , Qingcan Wang , Linjie Zhang , Guoqing Wei , Yue Tian , Kui Zhao , Ang Chen , Binghe Tan , Jiazhen Cui , Deqi Li , Yi Li , Yalei Qi , Dongrui Wang , Yuxuan Wu , Dali Li , Bing Du , Mingyao Liu , He Huang

Journal: Nature

PubMed ID: 36045296

Doi: 10.1038/s41586-022-05140-y

Products & Services: Synthetic sgRNA and crRNA Service

D-Lactic Acid Production from Sugarcane Bagasse by Genetically Engineered

Authors: Warasirin Sornlek, Kittapong Sae-Tang, Akaraphol Watcharawipas, Sriwan Wongwisansri, Sutipa Tanapongpipat, Lily Eurwilaichtr, Verawat Champreda, Weerawat Runguphan, Peter J Schaap, Vitor A P Martins Dos Santos

Journal: J Fungi (Basel)

PubMed ID: 36012804

Doi: 10.3390/jof8080816

Products & Services: Synthetic sgRNA and crRNA Service

Engineering cell morphology by CRISPR interference in Acinetobacter baylyi ADP1

Authors: Jin Luo, Elena Efimova, Daniel Christoph Volke, Ville Santala, Suvi Santala

Journal: Microb Biotechnol

PubMed ID: 36005297

Doi: 10.1111/1751-7915.14133

Products & Services: Synthetic sgRNA and crRNA Service

Disruption of nuclear envelope integrity as a possible initiating event in tauopathies

Authors: Marine Prissette, Wen Fury, Matthew Koss, Claudia Racioppi, Daria Fedorova, Ella Dragileva, Georgia Clarke, Taylor Pohl, John Dugan, Diana Ahrens, Joyce Chiu, Charleen Hunt, Chia-Jen Siao, Tara Young, Arijit Bhowmick, Vitaliy Rogulin, Mathieu Desclaux, Eric Y Hayden, Michael Podgorski, Min Gao, Lynn E Macdonald, David Frendewey, George D Yancopoulos, Brian Zambrowicz

Journal: Cell Rep

PubMed ID: 36001963

Doi: 10.1016/j.celrep.2022.111249

Products & Services: Synthetic sgRNA and crRNA Service

Platinum nanoparticles (PtNPs)-based CRISPR/Cas12a platform for detection of nucleic acid and protein in clinical samples

Authors: Jiajie Liang, Peijun Teng, Liangshan Hu, Guanbo He, Qifang Song, Ying Zhang, Bin Peng, Gan Li, Wei Xiao, Donglin Cao, Yong Tang

Journal: Anal Chim Acta

PubMed ID: 36038232

Doi: 10.1016/j.aca.2022.340203

Products & Services: Synthetic sgRNA and crRNA Service