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Therapeutic targeting nudix hydrolase 1 creates a MYC-driven metabolic vulnerability

Authors: Minhui Ye, Yingzhe Fang, Lu Chen, Zemin Song, Qing Bao, Fei Wang, Hao Huang, Jin Xu, Ziwen Wang, Ruijing Xiao, Meng Han, Song Gao, Hudan Liu, Baishan Jiang, Guoliang Qing

Journal: Nat Commun

PubMed ID: 38493213

Doi: 10.1038/s41467-024-46572-6

Products & Services: Synthetic sgRNA and crRNA Service

Mosquito E-20-Monooxygenase Gene Knockout Increases Dengue Virus Replication in Cells

Authors: Bo Li, Di Wang, Xiaoxue Xie, Xiaoli Chen, Guorui Liang, Dan Xing, Teng Zhao, Jiahong Wu, Xinyu Zhou, Chunxiao Li

Journal: Viruses

PubMed ID: 38675868

Doi: 10.3390/v16040525

Products & Services: Synthetic sgRNA and crRNA Service

Identification of closely related species in through Analysis of Whole-Genome

Authors: Guihong Qi, Lijun Hao, Yutong Gan, Tianyi Xin, Qian Lou, Wenjie Xu, Jingyuan Song

Journal: Front Microbiol

PubMed ID: 38450170

Doi: 10.3389/fmicb.2024.1323572

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A quaternary ammonium-based nanosystem enables delivery of CRISPR/Cas9 for cancer therapy

Authors: Mengzhu Zhang, Siyu Sun, Xiao Liang, Zengguang Liu, Jiaxin Yin, Quanshun Li, Shengcai Yang

Journal: Biomater Sci

PubMed ID: 38240497

Doi: 10.1039/d3bm01629c

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Characterization of N-glycosylation and its Functional Role in SIDT1-Mediated RNA Uptake

Authors: Tingting Yang, Haonan Xiao, Xiulan Chen, Le Zheng, Hangtian Guo, Jiaqi Wang, Xiaohong Jiang, Chen-Yu Zhang, Fuquan Yang, Xiaoyun Ji

Journal: J Biol Chem

PubMed ID: 38237680

Doi: 10.1016/j.jbc.2024.105654

Products & Services: Synthetic sgRNA and crRNA Service

Improving the Efficiency of CRISPR Ribonucleoprotein-Mediated Precise Gene Editing by Small Molecules in Porcine Fibroblasts

Authors: Yunjing Zhao, Xinyu Li, Chang Liu, Chaoqian Jiang, Xiaochen Guo, Qianqian Xu, Zhi Yin, Zhonghua Liu, Yanshuang Mu

Journal: Animals (Basel)

PubMed ID: 38473105

Doi: 10.3390/ani14050719

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A dual role of RBM42 in modulating splicing and translation of CDKN1A/p21 during DNA damage response

Authors: Bella M Ben-Oz, Feras E Machour, Marian Nicola, Amir Argoetti, Galia Polyak, Rawad Hanna, Oded Kleifeld, Yael Mandel-Gutfreund, Nabieh Ayoub

Journal: Nat Commun

PubMed ID: 37993446

Doi: 10.1038/s41467-023-43495-6

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Development of a highly efficient prime editor system in mice and rabbits

Authors: Yuqiang Qian , Di Wang , Wenchao Niu , Zheng Shi , Mao Wu , Ding Zhao , Jinze Li , Xun Gao , Zhongtian Zhang , Liangxue Lai , Zhanjun Li

Journal: Cell Mol Life Sci .

PubMed ID: 37924393

Doi: 10.1007/s00018-023-05003-3

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Unlocking the potential of allogeneic Vδ2 T cells for ovarian cancer therapy through CD16 biomarker selection and CAR/IL-15 engineering

Authors: Derek Lee, Zachary Spencer Dunn, Wenbin Guo, Carl J Rosenthal, Natalie E Penn, Yanqi Yu, Kuangyi Zhou, Zhe Li, Feiyang Ma, Miao Li, Tsun-Ching Song, Xinjian Cen, Yan-Ruide Li, Jin J Zhou, Matteo Pellegrini, Pin Wang, Lili Yang

Journal: Nat Commun

PubMed ID: 37938576

Doi: 10.1038/s41467-023-42619-2

Products & Services: Synthetic sgRNA and crRNA Service

A CRISPRCas12a-SERS platform for amplification-free detection of African swine fever virus genes

Authors: Huimin Wang , Ailing Su , Chengxin Bao , Chongyang Liang , Weiqing Xu , Jingjing Chang , Shuping Xu

Journal: Talanta .

PubMed ID: 37741267

Doi: 10.1016/j.talanta.2023.125225

Products & Services: Synthetic sgRNA and crRNA Service