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Brain-Targeting Delivery of Two Peptidylic Inhibitors for Their Combination Therapy in Transgenic Polyglutamine Disease Mice via Intranasal Administration

Authors: Yang M, Zhang Q, Wang Q, Sørensen KK, Boesen JT, Ma SY, Jensen KJ, Kwan KM, Ngo JCK, Chan HYE, Zuo Z

Journal: Molecular Pharmaceutics

PubMed ID: 30392378

Doi: 10.1021/acs.molpharmaceut.8b00938

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Recognition of the Diglycine C-End Degron by CRL2^KLHDC2 Ubiquitin Ligase

Authors: Rusnac DV, Lin HC, Canzani D, Tien KX, Hinds TR, Tsue AF, Bush MF, Yen HS, Zheng N

Journal: Molecular Cell

PubMed ID: 30526872

Doi: 10.1016/j.molcel.2018.10.021

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Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism

Authors: Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC

Journal: Cell

PubMed ID: 30392958

Doi: 10.1016/j.cell.2018.10.001

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Conjugation of urate-derived electrophiles to proteins during normal metabolism and inflammation

Authors: Turner R, Brennan SO, Ashby LV, Dickerhof N, Hamzah MR, Pearson JF, Stamp LK, Kettle AJ

Journal: The Journal of Biological Chemistry

PubMed ID: 30385504

Doi: 10.1074/jbc.RA118.005237

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Two Mutations Commonly Associated with Daptomycin Resistance in Enterococcus faecium LiaS^T120A and LiaR^W73C Appear To Function Epistatically in LiaFSR Signaling

Authors: Davlieva M, Wu C, Zhou Y, Arias CA, Shamoo Y

Journal: Biochemistry

PubMed ID: 30403130

Doi: 10.1021/acs.biochem.8b01072

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WRKY7, -11 and -17 transcription factors are modulators of the bZIP28 branch of the unfolded protein response during PAMP-triggered immunity in Arabidopsis thaliana.

Authors: Paulina Arrano-Salinas, Jos ˜ e Dom ´ ´ınguez-Figueroa,Ariel Herrera-Vasquez, Diego Zavala, Joaquin Medina, Jes ´ us´Vicente-Carbajosa, Claudio Meneses, Paulo Canessa, Adrian´A. Moreno, Francisca Blanco-Herrera

Journal: Plant Science

PubMed ID: 30466590

Doi: 10.1016/j.plantsci.2018.09.019

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A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates

Authors: Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A, Watanabe J, Usachenko J, Ardeshir A, Saeed M, Agudelo M, Eisenreich T, Bournazos S, Oliveira TY, Rice CM, Coffey LL, MacDonald MR, Bjorkman PJ, Nussenzweig MC, Robbiani DF

Journal: Cell Reports

PubMed ID: 30403995

Doi: 10.1016/j.celrep.2018.10.031

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Single-Molecule Discrimination of Labeled DNAs and Polypeptides Using Photoluminescent-Free TiO₂ Nanopores

Authors: Wang R, Gilboa T, Song J, Huttner D, Grinstaff MW, Meller A

Journal: ACS Nano

PubMed ID: 30372037

Doi: 10.1021/acsnano.8b07055

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Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection

Authors: Pack AD, Collins MH, Rosenberg CS, Tarleton RL

Journal: PLOS Pathogens

PubMed ID: 30419010

Doi: 10.1371/journal.ppat.1007410

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Modulation of proteoglycan receptor PTPσ enhances MMP-2 activity to promote recovery from multiple sclerosis

Authors: Luo F, Tran AP, Xin L, Sanapala C, Lang BT, Silver J, Yang Y

Journal: Nature Communications

PubMed ID: 30297691

Doi: 10.1038/s41467-018-06505-6

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