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The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex.
Authors: Trivedi Prasad,Palomba Francesco,Niedzialkowska Ewa,Digman Michelle A,Gratton Enrico,Stukenberg P
Journal: Nat Cell Biol
PubMed ID: 31481798
Doi: 10.1038/s41556-019-0376-4
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Putative Adhesion Factors in Vaginal Lactobacillus gasseri DSM 14869: Functional Characterization.
Authors: Zeng Zhu,Zuo Fanglei,Marcotte Ha
Journal: Appl Environ Microbiol
PubMed ID: 31420338
Doi: 10.1128/AEM.00800-19
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Discovery and characterization of CHO host cell protease-induced fragmentation of a recombinant monoclonal antibody during production process development.
Authors: YangBin,LiWenhua,ZhaoHui,WangAnling,LeiYuanjun,XieQiuling,XiongS
Journal: J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
PubMed ID: 30836312
Doi: 10.1016/j.jchromb.2019.02.020
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Linking (Pyr)apelin-13 pharmacokinetics to efficacy: Stabilization and measurement of a high clearance peptide in rodents.
Authors: OnoratoJoelle M,XuCarrie,ChenXue-Qing,RoseAnne V,GenerauxClaudia,LentzKimberley,ShipkovaPetia,ArthurSusan,HennanJames K,HaskellRoy,MyersMichael C,LawrenceR Michael,FinlayHeather J,BassoMichael,BostwickJeffrey,FernandoGayani,GarciaRicardo,HellingsSamuel,HsuMei-Yin,ZhangRongan,ZhaoLei,GargalovicP
Journal: Anal. Biochem.
PubMed ID: 30605634
Doi: 10.1016/j.ab.2018.12.022
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Deciphering the relative roles of matrix metalloproteinase- and plasmin-mediated matrix degradation during capillary morphogenesis using engineered hydrogels.
Authors: BeamishJeffrey A,JuliarBenjamin A,ClevelandDavid S,BuschMegan E,NimmagaddaLikitha,PutnamAndr
Journal: J. Biomed. Mater. Res. Part B Appl. Biomater.
PubMed ID: 30784190
Doi: 10.1002/jbm.b.34341
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MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer.
Authors: NovoplanskyOfra,FuryMatthew,PrasadManu,YegodayevKsenia,ZoreaJonathan,CohenLimor,PelossofRaphael,CohenLiz,KatabiNora,CecchiFabiola,JoshuaBen-Zion,PopovtzerAron,BaselgaJose,ScaltritiMaurizio,ElkabetsM
Journal: Int. J. Cancer
PubMed ID: 30694565
Doi: 10.1002/ijc.32170
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Heterotrimeric G proteins promote FLS2 protein accumulation through inhibition of FLS2 autophagic degradation
Authors: Jimi C. Miller, Stacey A. Lawrence, Nicole K. Clay
Journal: biorxiv
Doi: 10.1101/438135
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The Mitochondrial Peptide Humanin Targets but Does Not Denature Amyloid Oligomers in Type II Diabetes
Authors: Levine ZA, Teranishi K, Okada AK, Langen R, Shea JE.
Journal: J Am Chem Soc
PubMed ID: 31456396
Doi: 10.1021/jacs.9b04995
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Subcellular localization of Rap1 GTPase activator CalDAG-GEFI is orchestrated by interaction of its atypical C1 domain with membrane phosphoinositides.
Authors: Sarker M, Goliaei A, Golesi F, Poggi M, Cook AA, Khan MAI, Temple BR,, Stefanini L, Canault M, Bergmeier W,, Campbell SL,.
Journal: J Thromb Haemost
PubMed ID: 31758832
Doi: 10.1111/jth.14687
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Potential Tools for Eradicating HIV Reservoirs in the Brain: Development of Trojan Horse Prodrugs for the Inhibition of P-Glycoprotein with Anti-HIV-1 Activity.
Authors: Agrawal N, Rowe J, Lan J, Yu Q, Hrycyna CA, Chmielewski J.
Journal: J Med Chem
PubMed ID: 31505928
Doi: 10.1021/acs.jmedchem.9b00779
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