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MET activation confers resistance to cetuximab， and prevents HER2 and HER3 upregulation in head and neck cancer.

Authors: NovoplanskyOfra，FuryMatthew，PrasadManu，YegodayevKsenia，ZoreaJonathan，CohenLimor，PelossofRaphael，CohenLiz，KatabiNora，CecchiFabiola，JoshuaBen-Zion，PopovtzerAron，BaselgaJose，ScaltritiMaurizio，ElkabetsM

Journal: Int. J. Cancer

PubMed ID: 30694565

Doi: 10.1002/ijc.32170

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Discovery and characterization of CHO host cell protease-induced fragmentation of a recombinant monoclonal antibody during production process development.

Authors: YangBin，LiWenhua，ZhaoHui，WangAnling，LeiYuanjun，XieQiuling，XiongS

Journal: J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.

PubMed ID: 30836312

Doi: 10.1016/j.jchromb.2019.02.020

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Linking (Pyr)apelin-13 pharmacokinetics to efficacy: Stabilization and measurement of a high clearance peptide in rodents.

Authors: OnoratoJoelle M，XuCarrie，ChenXue-Qing，RoseAnne V，GenerauxClaudia，LentzKimberley，ShipkovaPetia，ArthurSusan，HennanJames K，HaskellRoy，MyersMichael C，LawrenceR Michael，FinlayHeather J，BassoMichael，BostwickJeffrey，FernandoGayani，GarciaRicardo，HellingsSamuel，HsuMei-Yin，ZhangRongan，ZhaoLei，GargalovicP

Journal: Anal. Biochem.

PubMed ID: 30605634

Doi: 10.1016/j.ab.2018.12.022

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A near infrared fluorescent probe for the detection and imaging of prolyl aminopeptidase activity in living cells.

Authors: Liu X , Zhang QY , Wang F , Jiang JH .

Journal: Analyst

PubMed ID: 31531498

Doi: 10.1039/c9an01303b

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Granulocyte-Colony Stimulating Factor Alters the Pharmacodynamic Properties of Cocaine in Female Mice.

Authors: Brady LJ, Hofford RS, Tat J, Calipari ES, Kiraly DD.

Journal: ACS Chem Neurosci

PubMed ID: 31479229

Doi: 10.1021/acschemneuro.9b00309

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Potential Tools for Eradicating HIV Reservoirs in the Brain: Development of Trojan Horse Prodrugs for the Inhibition of P-Glycoprotein with Anti-HIV-1 Activity.

Authors: Agrawal N, Rowe J, Lan J, Yu Q, Hrycyna CA, Chmielewski J.

Journal: J Med Chem

PubMed ID: 31505928

Doi: 10.1021/acs.jmedchem.9b00779

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Subcellular localization of Rap1 GTPase activator CalDAG-GEFI is orchestrated by interaction of its atypical C1 domain with membrane phosphoinositides.

Authors: Sarker M, Goliaei A, Golesi F, Poggi M, Cook AA, Khan MAI, Temple BR,, Stefanini L, Canault M, Bergmeier W,, Campbell SL,.

Journal: J Thromb Haemost

PubMed ID: 31758832

Doi: 10.1111/jth.14687

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Heterotrimeric G proteins promote FLS2 protein accumulation through inhibition of FLS2 autophagic degradation

Authors: Jimi C. Miller, Stacey A. Lawrence, Nicole K. Clay

Journal: biorxiv

Doi: 10.1101/438135

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The Mitochondrial Peptide Humanin Targets but Does Not Denature Amyloid Oligomers in Type II Diabetes

Authors: Levine ZA, Teranishi K, Okada AK, Langen R, Shea JE.

Journal: J Am Chem Soc

PubMed ID: 31456396

Doi: 10.1021/jacs.9b04995

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Plk1/Polo Phosphorylates Sas-4 at the Onset of Mitosis for an Efficient Recruitment of Pericentriolar Material to Centrosomes

Authors: Ramani A, Mariappan A, Gottardo M, Mandad S, Urlaub H, Avidor-Reiss T, Riparbelli M, Callaini G, Debec A, Feederle R, Gopalakrishnan J

Journal: Cell Reports

PubMed ID: 30590037

Doi: 10.1016/j.celrep.2018.11.102

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