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OMN6 a novel bioengineered peptide for the treatment of multidrug resistant Gram negative bacteria

Authors: Shira Mandel, Janna Michaeli, Noa Nur, Isabelle Erbetti, Jonathan Zazoun, Livia Ferrari, Antonio Felici, Moshe Cohen-Kutner, Niv Bachnoff

Journal: Sci Rep

PubMed ID: 33758343

Doi: 10.1038/s41598-021-86155-9

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Exploration of benzofuran-based compounds as potent and selective Plasmodium falciparum glycogen synthase kinase-3 (PfGSK-3) inhibitors

Authors: Chantalle Moolman, Rencia van der Sluis, Richard M Beteck, Lesetja J Legoabe

Journal: Bioorg Chem

PubMed ID: 33813310

Doi: 10.1016/j.bioorg.2021.104839

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Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

Authors: Alexandra C Walls, Marcos C Miranda, Minh N Pham, Alexandra Schäfer, Allison Greaney, Prabhu S Arunachalam, Mary-Jane Navarro, M Alejandra Tortorici, Kenneth Rogers, Megan A O'Connor, Lisa Shireff, Douglas E Ferrell, Natalie Brunette, Elizabeth Kepl, John Bowen, Samantha K Zepeda, Tyler Starr, Ching-Lin Hsieh, Brooke Fiala, Samuel Wrenn, Deleah Pettie, Claire Sydeman, Max Johnson, Alyssa Blackstone, Rashmi Ravichandran, Cassandra Ogohara, Lauren Carter, Sasha W Tilles, Rino Rappuoli, Derek T O'Hagan, Robbert Van Der Most, Wesley C Van Voorhis, Jason S McLellan, Harry Kleanthous, Timothy P Sheahan, Deborah H Fuller, Francois Villinger, Jesse Bloom, Bali Pulendran, Ralph Baric, Neil King, David Veesler

Journal: biorxiv

PubMed ID: 33758839

Doi: 10.1101/2021.03.15.435528

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Stabilization of Damaged Articular Cartilage with Hydrogel-Mediated Reinforcement and Sealing

Authors: Jay M Patel, Claudia Loebel, Kamiel S Saleh, Brian C Wise, Edward D Bonnevie, Liane M Miller, James L Carey, Jason A Burdick, Robert L Mauck

Journal: Adv Healthc Mater

PubMed ID: 33738988

Doi: 10.1002/adhm.202100315

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SOCS-1 inhibition of type I interferon restrains Staphylococcus aureus skin host defense

Authors: Nathan Klopfenstein, Stephanie L Brandt, Sydney Castellanos, Matthias Gunzer, Amondrea Blackman, C Henrique Serezani

Journal: PLoS Pathog

PubMed ID: 33690673

Doi: 10.1371/journal.ppat.1009387

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Exploiting albumin as a mucosal vaccine chaperone for robust generation of lung-resident memory T cells

Authors: Kavya Rakhra, Wuhbet Abraham, Chensu Wang, Kelly D Moynihan, Na Li, Nathan Donahue, Alexis D Baldeon, Darrell J Irvine

Journal: Sci Immunol

PubMed ID: 33741657

Doi: 10.1126/sciimmunol.abd8003

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The survival and function of IL-10-producing regulatory B cells are negatively controlled by SLAMF5

Authors: Lihi Radomir, Matthias P Kramer, Michal Perpinial, Nofar Schottlender, Stav Rabani, Keren David, Anna Wiener, Hadas Lewinsky, Shirly Becker-Herman, Rina Aharoni, Ron Milo, Claudia Mauri, Idit Shachar

Journal: Nat Commun

PubMed ID: 33767202

Doi: 10.1038/s41467-021-22230-z

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Daily rewiring of a neural circuit generates a predictive model of environmental light

Authors: Bryan J Song, Slater J Sharp, Dragana Rogulja

Journal: Sci Adv

PubMed ID: 33762336

Doi: 10.1126/sciadv.abe4284

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Production and purification of TRPV2 and TRPV5 for structural and functional studies

Authors: Edwin C Fluck, Ruth A Pumroy, Vera Y Moiseenkova-Bell

Journal: Methods Enzymol

PubMed ID: 34099181

Doi: 10.1016/bs.mie.2021.02.007

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Assembly of a dsRNA synthesizing complex: RNA-DEPENDENT RNA POLYMERASE 2 contacts the largest subunit of NUCLEAR RNA POLYMERASE IV

Authors: Vibhor Mishra, Jasleen Singh, Feng Wang, Yixiang Zhang, Akihito Fukudome, Jonathan C Trinidad, Yuichiro Takagi, Craig S Pikaard

Journal: Proc Natl Acad Sci U S A

PubMed ID: 33753485

Doi: 10.1073/pnas.2019276118

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