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Myeloid-derived suppressor cells support remyelination in a murine model of multiple sclerosis by promoting oligodendrocyte precursor cell survival, proliferation, and differentiation
Authors: Melero-Jerez C,Fernández-Gómez B,Lebrón-Galán R,Ortega MC,Sánchez-de Lara I,Ojalvo AC,Clemente D,de Castro F
Journal: Glia
PubMed ID: 33217041
Doi: 10.1002/glia.23936
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Intradermal delivery of a synthetic DNA vaccine protects macaques from Middle East respiratory syndrome coronavirus
Authors: Ami Patel, Emma L Reuschel, Ziyang Xu, Faraz I Zaidi, Kevin Y Kim, Dana P Scott, Janess Mendoza, Stephanie Ramos, Regina Stoltz, Friederike Feldmann, Atsushi Okumura, Kimberly Meade-White, Elaine Haddock, Tina Thomas, Rebecca Rosenke, Jamie Lovaglio, Patrick W Hanley, Greg Saturday, Kar Muthumani, Heinz Feldmann, Laurent M Humeau, Kate E Broderick, David B Weiner
Journal: JCI Insight
PubMed ID: 33886507
Doi: 10.1172/jci.insight.146082
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H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum
Authors: Jessica Connacher, Gabrielle A Josling, Lindsey M Orchard, Janette Reader, Manuel Llinás, Lyn-Marié Birkholtz
Journal: Epigenetics Chromatin
PubMed ID: 33794978
Doi: 10.1186/s13072-021-00393-9
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Dynamic allostery controls the peptide sensitivity of the Ly49C natural killer receptor
Authors: Jiaqi Ma, Cory M Ayres, Lance M Hellman, Jason R Devlin, Brian M Baker
Journal: J Biol Chem
PubMed ID: 33891944
Doi: 10.1016/j.jbc.2021.100686
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Machine learning guided aptamer refinement and discovery
Authors: Ali Bashir, Qin Yang, Jinpeng Wang, Stephan Hoyer, Wenchuan Chou, Cory McLean, Geoff Davis, Qiang Gong, Zan Armstrong, Junghoon Jang, Hui Kang, Annalisa Pawlosky, Alexander Scott, George E Dahl, Marc Berndl, Michelle Dimon, B Scott Ferguson
Journal: Nat Commun
PubMed ID: 33888692
Doi: 10.1038/s41467-021-22555-9
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Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase
Authors: Nguyen S,Jovcevski B,Pukala TL,Bruning JB
Journal: The FEBS journal
PubMed ID: 33089641
Doi: 10.1111/febs.15607
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CD8 T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity
Authors: Thi H O Nguyen, Louise C Rowntree, Jan Petersen, Brendon Y Chua, Luca Hensen, Lukasz Kedzierski, Carolien E van de Sandt, Priyanka Chaurasia, Hyon-Xhi Tan, Jennifer R Habel, Wuji Zhang, Lilith F Allen, Linda Earnest, Kai Yan Mak, Jennifer A Juno, Kathleen Wragg, Francesca L Mordant, Fatima Amanat, Florian Krammer, Nicole A Mifsud, Denise L Doolan, Katie L Flanagan, Sabrina Sonda, Jasveen Kaur, Linda M Wakim, Glen P Westall, Fiona James, Effie Mouhtouris, Claire L Gordon, Natasha E Holmes, Olivia C Smibert, Jason A Trubiano, Allen C Cheng, Peter Harcourt, Patrick Clifton, Jeremy Chase Crawford, Paul G Thomas, Adam K Wheatley, Stephen J Kent, Jamie Rossjohn, Joseph Torresi, Katherine Kedzierska
Journal: Immunity
PubMed ID: 33951417
Doi: 10.1016/j.immuni.2021.04.009
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PRMT1-mediated H4R3me2a recruits SMARCA4 to promote colorectal cancer progression by enhancing EGFR signaling
Authors: Bing Yao, Tao Gui, Xiangwei Zeng, Yexuan Deng, Zhi Wang, Ying Wang, Dongjun Yang, Qixiang Li, Peipei Xu, Ruifeng Hu, Xinyu Li, Bing Chen, Jin Wang, Ke Zen, Haitao Li, Melissa J Davis, Marco J Herold, Hua-Feng Pan, Zhi-Wei Jiang, David C S Huang, Ming Liu, Junyi Ju, Quan Zhao
Journal: Genome Med
PubMed ID: 33853662
Doi: 10.1186/s13073-021-00871-5
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Gammaherpesvirus Usurps Host IL-17 Signaling To Support the Establishment of Chronic Infection
Authors: C N Jondle, K E Johnson, C Aurubin, P Sylvester, G Xin, W Cui, A R Huppler, V L Tarakanova
Journal: MBio
PubMed ID: 33824206
Doi: 10.1128/mBio.00566-21
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Adjuvanting a subunit COVID-19 vaccine to induce protective immunity
Authors: Prabhu S Arunachalam, Alexandra C Walls, Nadia Golden, Caroline Atyeo, Stephanie Fischinger, Chunfeng Li, Pyone Aye, Mary Jane Navarro, Lilin Lai, Venkata Viswanadh Edara, Katharina Röltgen, Kenneth Rogers, Lisa Shirreff, Douglas E Ferrell, Samuel Wrenn, Deleah Pettie, John C Kraft, Marcos C Miranda, Elizabeth Kepl, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Alexander G White, Meera Trisal, Ching-Lin Hsieh, Kasi Russell-Lodrigue, Christopher Monjure, Jason Dufour, Skye Spencer, Lara Doyle-Meyers, Rudolph P Bohm, Nicholas J Maness, Chad Roy, Jessica A Plante, Kenneth S Plante, Alex Zhu, Matthew J Gorman, Sally Shin, Xiaoying Shen, Jane Fontenot, Shakti Gupta, Derek T O'Hagan, Robbert Van Der Most, Rino Rappuoli, Robert L Coffman, David Novack, Jason S McLellan, Shankar Subramaniam, David Montefiori, Scott D Boyd, JoAnne L Flynn, Galit Alter, Francois Villinger, Harry Kleanthous, Jay Rappaport, Mehul S Suthar, Neil P King, David Veesler, Bali Pulendran
Journal: Nature
PubMed ID: 33873199
Doi: 10.1038/s41586-021-03530-2
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