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Nitration of protein kinase G-Iα modulates cyclic nucleotide crosstalk via phosphodiesterase 3A: Implications for acute lung injury

Authors: Evgeny A Zemskov, Xiaomin Wu, Saurabh Aggarwal, Mannivannan Yegambaram, Christine Gross, Qing Lu, Hui Wang, Haiyang Tang, Ting Wang, Stephen M Black

Journal: J Biol Chem

PubMed ID: 34252457

Doi: 10.1016/j.jbc.2021.100946

Products & Services: Mammalian Expression

Function of cofactor Akirin2 in the regulation of gene expression in model human Caucasian neutrophil-like HL60 cells

Authors: Sara Artigas-Jerónimo, Margarita Villar, Agustín Estrada-Peña, Adrián Velázquez-Campoy, Pilar Alberdi, José de la Fuente

Journal: Biosci Rep

PubMed ID: 34291801

Doi: 10.1042/BSR20211120

Products & Services: Mammalian Expression

Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth

Authors: Fangrui Wu, Shenyou Nie, Yuan Yao, Tong Huo, Xin Li, Xiaowei Wu, Jidong Zhao, Yi-Lun Lin, Yinjie Zhang, Qianxing Mo, Yongcheng Song

Journal: Theranostics

PubMed ID: 34373735

Doi: 10.7150/thno.56737

Products & Services: Mammalian Expression

Machine learning analyses of antibody somatic mutations predict immunoglobulin light chain toxicity

Authors: Maura Garofalo, Luca Piccoli, Margherita Romeo, Maria Monica Barzago, Sara Ravasio, Mathilde Foglierini, Milos Matkovic, Jacopo Sgrignani, Raoul De Gasparo, Marco Prunotto, Luca Varani, Luisa Diomede, Olivier Michielin, Antonio Lanzavecchia, Andrea Cavalli

Journal: Nat Commun

PubMed ID: 34112780

Doi: 10.1038/s41467-021-23880-9

Products & Services: Mammalian Expression

Prdx1 Interacts with ASK1 upon Exposure to HO and Independently of a Scaffolding Protein

Authors: Trung Nghia Vo, Julia Malo Pueyo, Khadija Wahni, Daria Ezeriņa, Jesalyn Bolduc, Joris Messens

Journal: Antioxidants (Basel)

PubMed ID: 34209102

Doi: 10.3390/antiox10071060

Products & Services: Mammalian Expression

Synthetic conjugate peptide Fba-Met6 (MP12) induces complement-mediated resistance against disseminated Candida albicans

Authors: Abby L Adams, Karen Eberle, Jonothan Rosario Colón, Evan Courville, Hong Xin

Journal: Vaccine

PubMed ID: 34127293

Doi: 10.1016/j.vaccine.2021.06.001

Products & Services: Mammalian Expression

Evaluation of Benzylpenicillin as an Internal Standard for Measurement of Piperacillin Bone Concentrations via Microdialysis

Authors: Martin Bruun Knudsen, Mats Bue, Louise L Pontoppidan, Magnus A Hvistendahl, Kjeld S?balle, Maiken Stilling, Pelle Hanberg

Journal: J Pharm Sci

PubMed ID: 34102200

Doi: 10.1016/j.xphs.2021.06.008

Products & Services: Mammalian Expression

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Authors: Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu, Xisong Ke

Journal: Sci Rep

PubMed ID: 34108553

Doi: 10.1038/s41598-021-91708-z

Products & Services: Mammalian Expression

Mutation-induced dimerization of transforming growth factor-β-induced protein (TGFBIp) may drive protein aggregation in granular corneal dystrophy

Authors: Nadia Sukusu Nielsen, Trine A F Gadeberg, Ebbe Toftgaard Poulsen, Seandean Lykke Harwood, Christian E Weberskov, Jan Skov Pedersen, Gregers R Andersen, Jan J Enghild

Journal: J Biol Chem

PubMed ID: 34097874

Doi: 10.1016/j.jbc.2021.100858

Products & Services: Mammalian Expression

Validating TDP1 as an Inhibition Target for the Development of Chemosensitizers for Camptothecin-Based Chemotherapy Drugs

Authors: Euphemia Leung, Jinal Patel, Jennifer A Hollywood, Ayesha Zafar, Petr Tomek, David Barker, Lisa I Pilkington, Michelle van Rensburg, Ries J Langley, Nuala A Helsby, Christopher J Squire, Bruce C Baguley, William A Denny, Jóhannes Reynisson, Ivanhoe K H Leung

Journal: Oncol Ther

PubMed ID: 34159519

Doi: 10.1007/s40487-021-00158-0

Products & Services: Mammalian Expression