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Reconstitution of human CMG helicase ubiquitylation by CUL2LRR1 and multiple E2 enzymes

Authors: Thanh Thi Le, Johanna Ainsworth, Cristian Polo Rivera, Thomas Macartney, Karim P M Labib

Journal: Biochem J

PubMed ID: 34195792

Doi: 10.1042/BCJ20210315

Products & Services: Mammalian Expression

Long-chain polyphosphates impair SARS-CoV-2 infection and replication

Authors: Veronica Ferrucci, Dae-Young Kong, Fatemeh Asadzadeh, Laura Marrone, Angelo Boccia, Roberto Siciliano, Giuseppina Criscuolo, Camilla Anastasio, Fabrizio Quarantelli, Marika Comegna, Ida Pisano, Margherita Passariello, Ilaria Iacobucci, Rosa Della Monica, Barbara Izzo, Pellegrino Cerino, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Bianca Maria Pierri, Giorgia Borriello, Claudia Tiberio, Luigi Atripaldi, Martina Bianchi, Giovanni Paolella, Ettore Capoluongo, Giuseppe Castaldo, Lorenzo Chiariotti, Maria Monti, Claudia De Lorenzo, Kyong-Seop Yun, Stefano Pascarella, Jae-Ho Cheong, Hong-Yeoul Kim, Massimo Zollo

Journal: Sci Signal

PubMed ID: 34230209

Doi: 10.1126/scisignal.abe5040

Products & Services: Mammalian Expression

Tobacco BY2 cells expressing recombinant cardosin B as an alternative for production of active milk clotting enzymes

Authors: André Folgado, Rita Abranches

Journal: Sci Rep

PubMed ID: 34262119

Doi: 10.1038/s41598-021-93882-6

Products & Services: Mammalian Expression

Human Hyaluronidase PH20 Potentiates the Antitumor Activities of Mesothelin-Specific CAR-T Cells Against Gastric Cancer

Authors: Ruocong Zhao, Yuanbin Cui, Yongfang Zheng, Shanglin Li, Jiang Lv, Qiting Wu, Youguo Long, Suna Wang, Yao Yao, Wei Wei, Jie Yang, Bin-Chao Wang, Zhenfeng Zhang, Hui Zeng, Yangqiu Li, Peng Li

Journal: Front Immunol

PubMed ID: 34326835

Doi: 10.3389/fimmu.2021.660488

Products & Services: Mammalian Expression

Degradation of CCNK/CDK12 is a druggable vulnerability of colorectal cancer

Authors: Sebastian M Dieter, Christine Siegl, Paula L Codó, Mario Huerta, Anna L Ostermann-Parucha, Erik Schulz, Martina K Zowada, Sylvia Martin, Karin Laaber, Ali Nowrouzi, Mona Blatter, Sina Kreth, Frank Westermann, Axel Benner, Ulrike Uhrig, Kerstin Putzker, Joe Lewis, Andrea Haegebarth, Dominik Mumberg, Simon J Holton, Joerg Weiske, Lena-Marit Toepper, Ulrike Scheib, Gerhard Siemeister, Claudia R Ball, Bernhard Kuster, Gabriele Stoehr, Hannes Hahne, Sarah Johannes, Martin Lange, Friederike Herbst, Hanno Glimm

Journal: Cell Rep

PubMed ID: 34289372

Doi: 10.1016/j.celrep.2021.109394

Products & Services: Mammalian Expression

RNA-Protein Interaction Analysis of SARS-CoV-2 5' and 3' Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

Authors: Rohit Verma, Sandhini Saha, Shiv Kumar, Shailendra Mani, Tushar Kanti Maiti, Milan Surjit

Journal: mSystems

PubMed ID: 34254825

Doi: 10.1128/mSystems.00643-21

Products & Services: Mammalian Expression

CCR2 Regulates Vaccine-Induced Mucosal T-Cell Memory to Influenza A Virus

Authors: Woojong Lee, Brock Kingstad-Bakke, Ross M Kedl, Yoshihiro Kawaoka, M Suresh

Journal: J Virol

PubMed ID: 33952647

Doi: 10.1128/JVI.00530-21

Products & Services: Mammalian Expression

Enzymatic activation of pyruvate kinase increases cytosolic oxaloacetate to inhibit the Warburg effect

Authors: Elizabeth K Wiese, Sadae Hitosugi, Sharon T Loa, Annapoorna Sreedhar, Lindsey G Andres-Beck, Kiran Kurmi, Yuan-Ping Pang, Larry M Karnitz, Wilson I Gonsalves, Taro Hitosugi

Journal: Nat Metab

PubMed ID: 34226744

Doi: 10.1038/s42255-021-00424-5

Products & Services: Mammalian Expression

A homozygous stop-gain variant in ARHGAP42 is associated with childhood interstitial lung disease, systemic hypertension, and immunological findings

Authors: Qifei Li , Michal Dibus , Alicia Casey , Christina S K Yee , Sara O Vargas , Shiyu Luo , Samantha M Rosen, Jill A Madden , Casie A Genetti , Jan Brabek , Catherine A Brownstein , Shideh Kazerounian, Benjamin A Raby , Klaus Schmitz-Abe , John C Kennedy, Martha P Fishman, Mary P Mullen, Joan M Taylor, Daniel Rosel, Pankaj B Agrawal

Journal: PLoS Genet

PubMed ID: 34232960

Doi: 10.1371/journal.pgen.1009639

Products & Services: Mammalian Expression

Function of cofactor Akirin2 in the regulation of gene expression in model human Caucasian neutrophil-like HL60 cells

Authors: Sara Artigas-Jerónimo, Margarita Villar, Agustín Estrada-Peña, Adrián Velázquez-Campoy, Pilar Alberdi, José de la Fuente

Journal: Biosci Rep

PubMed ID: 34291801

Doi: 10.1042/BSR20211120

Products & Services: Mammalian Expression