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A platform for deep sequence-activity mapping and engineering antimicrobial peptides

Authors: Matthew P. DeJong; Seth C. Ritter; Katharina A. Fransen; Daniel T. Tresnak; Alexander W. Golinski; Benjamin J. Hackel

Journal: ACS Synthetic Biology

PubMed ID: 34506711

Doi: 10.1021/acssynbio.1c00314

Products & Services: Peptide Synthesis

Secondary Structure of the Novel Myosin Binding Domain WYR and Implications within Myosin Structure

Authors: Lynda M Menard, Neil B Wood, Jim O Vigoreaux

Journal: Biology (Basel)

PubMed ID: 34209926

Doi: 10.3390/biology10070603

Products & Services: Peptide Synthesis

Model infant biscuits release the opioid-acting peptides milk β-casomorphins and gluten exorphins after in vitro gastrointestinal digestion

Authors: Valentina Pica, Milda Stuknytė, Fabio Masotti, Ivano De Noni, Stefano Cattaneo

Journal: Food Chem

PubMed ID: 34118509

Doi: 10.1016/j.foodchem.2021.130262

Products & Services: Peptide Synthesis

Antibody Levels to Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLγ11 and DBLδ-1 Predict Reduction in Parasite Density

Authors: Brittany N Araj, Bruce Swihart, Robert Morrison, Patricia Gonzales Hurtado, Andrew Teo, Almahamoudou Mahamar, Oumar Attaher, Bacary S Diarra, Santara Gaoussou, Djibrilla Issiaka, Alassane Dicko, Patrick E Duffy, Michal Fried

Journal: mSystems

PubMed ID: 34128693

Doi: 10.1128/mSystems.00347-21

Products & Services: Peptide Synthesis

Recruitment of phospholipase Cγ1 to the non-structural membrane protein pK15 of Kaposi Sarcoma-associated herpesvirus promotes its Src-dependent phosphorylation

Authors: Naira Samarina, George Ssebyatika, Tanvi Tikla, Ja-Yun Waldmann, Bizunesh Abere, Vittoria Nanna, Michelangelo Marasco, Teresa Carlomagno, Thomas Krey, Thomas F Schulz

Journal: PLoS Pathog

PubMed ID: 34143834

Doi: 10.1371/journal.ppat.1009635

Products & Services: Peptide Synthesis

The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide

Authors: Juan Pablo Robles, Magdalena Zamora, Lourdes Siqueiros-Marquez, Elva Adan-Castro, Gabriela Ramirez-Hernandez, Francisco Freinet Nuñez, Fernando Lopez-Casillas, Robert P Millar, Thomas Bertsch, Gonzalo Martínez de la Escalera, Jakob Triebel, Carmen Clapp

Journal: Angiogenesis

PubMed ID: 34097181

Doi: 10.1007/s10456-021-09800-x

Products & Services: Peptide Synthesis

Membrane Env Liposomes Facilitate Immunization with Multivalent Full-Length HIV Spikes

Authors: Daniel P Leaman, Armando Stano, Yajing Chen, Lei Zhang, Michael B Zwick

Journal: J Virol

PubMed ID: 33883221

Doi: 10.1128/JVI.00005-21

Products & Services: Peptide Synthesis

Rational selection of hidden epitopes for a molecularly imprinted electrochemical sensor in the recognition of heat-denatured dengue NS1 protein

Authors: Matheus Siqueira Silva, Ana Patricia Moreira Tavares, Luiz Felipe Leomil Coelho, Lígia Ely Morganti Ferreira Dias, Rosa Maria Chura-Chambi, Flávio Guimarães da Fonseca, Maria Goreti Ferreira Sales, Eduardo Costa Figueiredo

Journal: Biosens Bioelectron

PubMed ID: 34144470

Doi: 10.1016/j.bios.2021.113419

Products & Services: Peptide Synthesis

A methyl esterase 1 (PvMES1) promotes the salicylic acid pathway and enhances Fusarium wilt resistance in common beans

Authors: Renfeng Xue, Ming Feng, Jian Chen, Weide Ge, Matthew W Blair

Journal: Theor Appl Genet

PubMed ID: 34128089

Doi: 10.1007/s00122-021-03830-1

Products & Services: Peptide Synthesis

Discovery of a Myeloid Cell Leukemia 1 (Mcl-1) Inhibitor That Demonstrates Potent In Vivo Activities in Mouse Models of Hematological and Solid Tumors

Authors: James C. Tarr; James M. Salovich; Martin Aichinger; KyuOk Jeon; Nagarathanam Veerasamy; John L. Sensintaffar; Heribert Arnhof; Matthias Samwer; Plamen P. Christov; Kwangho Kim; Tobias Wunberg; Norbert Schweifer; Francesca Trapani; Allison Arnold; Florian Martin; Bin Zhao; Nagaraju Miriyala; Danielle Sgubin; Stuart Fogarty; William J. Moore; Gordon M. Stott; Edward T. Olejniczak; Harald Engelhardt; Dorothea Rudolph; Taekyu Lee; Darryl B. McConnell; Stephen W. Fesik

Journal: Journal of Medicinal Chemistry

PubMed ID: 39102508

Doi: 10.1021/acs.jmedchem.4c01188

Products & Services: Peptide Synthesis