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Lipid-organized tetramerization of PLPP1 defines the molecular basis of spatial lipid phosphate signaling

Authors: Yunhai Li, Qingning Yuan, Zhenyu Cao, Liuqing Zhu, Jiuyin Xu, Cheng-Cen Guo, James Jiqi Wang, Youwei Xu, Shuai Li, Tianyu Li, Yang Li, Yong Li, H. Eric Xu, Canrong Wu

Journal: Nature Communications

Doi: 10.1038/s41467-026-78196-3

Products & Services: Peptide Synthesis

Ultrasound-Driven Lysis of Tumor-Resident Bacteria Awakens Innate Immunity for Systemic Cancer Therapy

Authors: Wenya Zhou, Haoqi Zhu, Yu Liu, Haoze Li, Min Wu, Siqi Li, Rui Qu, Shaopeng Liu, Hanqing Qian, Bin Xue, Yi Cao, Xiqun Jiang, Xu Zhen

Journal: Journal of the American Chemical Society

Doi: 10.1021/jacs.6c14587

Products & Services: Peptide Synthesis

IRF2BP2-FOSL2 interaction regulates SOX9-mediated cartilage regeneration in osteoarthritis models

Authors: Hao Zhou, Tiantian Lu, Zhuoqun Gao, Can Cui, Zhiqiang Fang, Yu You, Jing Jiang, Jinjin Xu, Fang Wei, Jing Yu, Hu Zhou, Jinsong Li, Jian Luo, Lei Zhang, Yunyun Jin

Journal: JOURNAL OF CLINICAL INVESTIGATION

PubMed ID: 42878073

Doi: 10.1172/JCI200039

Products & Services: Peptide Synthesis

Molecular Programming of Steric Tags for Controlled Nanopore Translocation toward Precision Clinical Diagnostic Assistance

Authors: Heng Liu, Shijun Lin, Minglun Li, Hao Fang, Zhicheng Zhang, Ruwei Wei, Yan Zhang, Jun Dai, Tao Liu, Fan Xia, Xiaoding Lou

Journal: Journal of the American Chemical Society

Doi: doi.org/10.1021/jacs.6c15448

Products & Services: Peptide Synthesis

Rabeprazole exhibits broad-spectrum fusion inhibition against Nipah pseudovirus and authentic HCoV-OC43 and RSV

Authors: Yunyue Shen, Boxuan Wang, Jie Li, Ze Liang, Lili Liu, Guang Yang, Lei Yan

Journal: Bioorganic Chemistry

PubMed ID: 42607444

Doi: doi.org/10.1016/j.bioorg.2026.110387

Products & Services: Peptide Synthesis

An Ancestral Mechanism of Calmodulin Binding to Cds1 Kinase Inhibits Catalytic Activity

Authors: Stephanie A Manovella, Tingting Wang, Samuel N Young, Toby A Dite, Vineet Vaibhav, Steve Binos, Laura F Dagley, Anh T N Nguyen, Anthony R Means, Janni Petersen, John W Scott, James M Murphy, Christopher R Horne

Journal: IUBMB Life

PubMed ID: 42655879

Doi: 10.1002/iub.70128.

Products & Services: Peptide Synthesis

PepGate: A Dual-Path Diffusion Framework for ACE Inhibitory Peptide De Novo Design

Authors: Wanhao Sun, Xihe Yang, Xin Huang, Neng Xiong, Hongru Feng, Yuanjiang Pan

Journal: Journal of Medicinal Chemistry

Doi: 10.1021/acs.jmedchem.6c01875

Products & Services: Peptide Synthesis

Novel antimicrobial peptides derived from Brevibacillus laterosporus DSM 25 targeting MurT ligase exhibit broad-spectrum activity against drug-resistant pathogens

Authors: Nupur Pathak, V. Kohila

Journal: Scientific Reports

Doi: 10.1038/s41598-026-61205-2

Products & Services: Peptide Synthesis

Augmenting macropinocytosis enhances the apoptotic body-mediated tumor deep penetration of nanomedicines

Authors: Bin Wan, Qiu Wang, Xiwei Jiang, Xianlu Zhang, Xiaoyuan Fan, Fengxiang Liu, Shipeng Ning, Meiling Zhang, Dongyan Liang, Lianwen Qi, Zhonggui He, Yinglei Zhai, Kaiyuan Wang, Jin Sun, Wei Tang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.112285

Products & Services: Peptide Synthesis

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol-Mediated Cellular Uptake for miRNA Nano-Drugs

Authors: Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan

Journal: Advanced science

PubMed ID: 42658549

Doi: 10.1002/advs.77389

Products & Services: Peptide Synthesis