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Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma

Authors: Marisa E Aikins, You Qin, Hannah E Dobson, Alireza Hassani Najafabadi, Kexing Lyu, Yao Xu, Ying Xin, Anna Schwendeman, Max S Wicha, Alfred E Chang, Qiao Li, James J Moon

Journal: J Control Release

PubMed ID: 36206945

Doi: 10.1016/j.jconrel.2022.09.061

Products & Services: Peptide Synthesis

Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice

Authors: Shiwen Peng, Deyin Xing, Louise Ferrall, Ya-Chea Tsai, Chien-Fu Hung, T-C Wu

Journal: J Biomed Sci

PubMed ID: 36224625

Doi: 10.1186/s12929-022-00864-5

Products & Services: Peptide Synthesis

Peroxynitrite in the tumor microenvironment changes the profile of antigens allowing escape from cancer immunotherapy

Authors: Evgenii N Tcyganov, Emilio Sanseviero, Douglas Marvel, Thomas Beer, Hsin-Yao Tang, Peter Hembach, David W Speicher, Qianfei Zhang, Laxminarasimha R Donthireddy, Ali Mostafa, Sabina Tsyganova, Vladimir Pisarev, Terri Laufer, Dmitriy Ignatov, Soldano Ferrone, Christiane Meyer, Hélène Maby-El Hajjami, Daniel E Speiser, Sooner Altiok, Scott Antonia, Xiaowei Xu, Wei Xu, Cathy Zheng, Lynn M Schuchter, Ravi K Amaravadi, Tara C Mitchell, Giorgos C Karakousis, Zhe Yuan, Luis J Montaner, Esteban Celis, Dmitry I Gabrilovich

Journal: Cancer Cell

PubMed ID: 36220073

Doi: 10.1016/j.ccell.2022.09.001

Products & Services: Peptide Synthesis

Mannose and Hyaluronic Acid Dual-Modified Iron Oxide Enhances Neoantigen-Based Peptide Vaccine Therapy by Polarizing Tumor-Associated Macrophages

Authors: Ying Nie , Lu Shi , Yanan Zhang , Yunfei Guo , Hongchen Gu

Journal: Cancers

PubMed ID: 36291890

Doi: /10.3390/cancers14205107

Products & Services: Peptide Synthesis

Nitric oxide-driven modifications of lipoic arm inhibit α-ketoacid dehydrogenases

Authors: Gretchen L Seim, Steven V John, Nicholas L Arp, Zixiang Fang, David J Pagliarini, Jing Fan

Journal: Nat Chem Biol

PubMed ID: 36266351

Doi: 10.1038/s41589-022-01153-w

Products & Services: Peptide Synthesis

Isolation of a Peptide That Binds to Lytic Bacteriophage

Authors: Soo Khim Chan, Zhongchao Zhao, Samuel Penziner, Ethan Khong, David Pride, Robert T Schooley, Nicole F Steinmetz

Journal: ACS Omega

PubMed ID: 36312416

Doi: 10.1021/acsomega.2c05539

Products & Services: Peptide Synthesis

A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer

Authors: Kristin A Altwegg, Suryavathi Viswanadhapalli, Monica Mann, Dimple Chakravarty, Samaya Krishnan, Zexuan Liu, Junhao Liu, Uday P Pratap, Behnam Ebrahimi, John R Sanchez, Xiaonan Li, Shihong Ma, Ben H Park, Bindu Santhamma, Yidong Chen, Zhao Lai, Ganesh V Raj, Yaxia Yuan, Daohong Zhou, Gangadhara R Sareddy, Rajeshwar R Tekmal, Stan McHardy, Tim H-M Huang, Manjeet K Rao, Hariprasad Vankayalapati, Ratna K Vadlamudi

Journal: Cancer Res

PubMed ID: 35950923

Doi: 10.1158/0008-5472.CAN-22-0698

Products & Services: Peptide Synthesis

Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition

Authors: Wei-Hung Chen, JungHyun Kim, Wei Bu, Nathan L Board, Yaroslav Tsybovsky, Yanmei Wang, Anna Hostal, Sarah F Andrews, Rebecca A Gillespie, Misook Choe, Tyler Stephens, Eun Sung Yang, Amarendra Pegu, Caroline E Peterson, Brian E Fisher, John R Mascola, Stefania Pittaluga, Adrian B McDermott, Masaru Kanekiyo, M Gordon Joyce, Jeffrey I Cohen

Journal: Immunity

PubMed ID: 36306784

Doi: 10.1016/j.immuni.2022.10.003

Products & Services: Peptide Synthesis

Structural basis for product specificities of MLL family methyltransferases

Authors: Yanjing Li , Lijie Zhao , Yuebin Zhang , Ping Wu , Ying Xu , Jun Mencius , Yongxin Zheng , Xiaoman Wang , Wancheng Xu , Naizhe Huang , Xianwen Ye , Ming Lei , Pan Shi , Changlin Tian , Chao Peng , Guohui Li , Zhijun Liu , Shu Quan , Yong Chen

Journal: Mol Cell

PubMed ID: 36108631

Doi: 10.1016/j.molcel.2022.08.022

Products & Services: Peptide Synthesis

A bacterial phospholipid phosphatase inhibits host pyroptosis by hijacking ubiquitin

Authors: Qiyao Chai , Shanshan Yu, Yanzhao Zhong , Zhe Lu , Changgen Qiu, Yang Yu , Xinwen Zhang , Yong Zhang, Zehui Lei, Lihua Qiang, Bing-Xi Li, Yu Pang, Xiao-Bo Qiu, Jing Wang , Cui Hua Liu

Journal: Science .

PubMed ID: 36227980

Doi: 10.1126/science.abq0132

Products & Services: DNA Sequencing Peptide Synthesis