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Genetic regulation of TERT splicing affects cancer risk by altering cellular longevity and replicative potential
Authors: Oscar Florez-Vargas, Michelle Ho, Maxwell H Hogshead, Brenen W Papenberg, Chia-Han Lee, Kaitlin Forsythe, Kristine Jones, Wen Luo, Kedest Teshome, Cornelis Blauwendraat, Kimberly J Billingsley, Mikhail Kolmogorov, Melissa Meredith, Benedict Paten, Raj Chari, Chi Zhang, John S Schneekloth, Mitchell J Machiela, Stephen J Chanock, Shahinaz M Gadalla, Sharon A Savage, Sam M Mbulaiteye, Ludmila Prokunina-Olsson
Journal: Nature Communications
PubMed ID: 39956830
Doi: 10.1038/s41467-025-56947-y
Products & Services: Custom Vector Construction   
ABC transporter activity is affected by the size of lipid nanodiscs
Authors: Annabella Nouel Barreto, Luis G Cuello, Maria E Zoghbi
Journal: FEBS Letters
PubMed ID: 39748569
Doi: 10.1002/1873-3468.15096
Products & Services: Gene Synthesis   Custom Vector Construction   
Synthetic lethality of mRNA quality control complexes in cancer
Authors: Vivian Prindle, Adam E Richardson, Kimberly R Sher, Sarah Kongpachith, Kaitlin Kentala, Sakina Petiwala, Dong Cheng, Deborah Widomski, Phuong Le, Maricel Torrent, Anlu Chen, Stephen Walker, Marianne B Palczewski, Diya Mitra, Vlasios Manaves, Xu Shi, Charles Lu, Stephanie Sandoval, Zoltan Dezso, F Gregory Buchanan, Daniel Verduzco, Brian Bierie, Jonathan A Meulbroek, William N Pappano, Joshua P Plotnik
Journal: Nature
PubMed ID: 39910291
Doi: 10.1038/s41586-024-08398-6
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LCK-co-receptor association ensures T cell lineage fidelity and maximizes epitope-specific TCR diversity
Authors: Justin B Zhang, Priyanka Chaurasia, Angela Nguyen, Zijian Huang, Trang T Nguyen, Hui Xu, Mai T Tran, Hugh H Reid, Claerwen M Jones, Stefan A Schattgen, Daniel Thiele, Paul G Thomas, Jeanette Rientjes, Kim L Good-Jacobson, Roland Ruscher, Dene R Littler, Jamie Rossjohn, Pirooz Zareie, Nicole L La Gruta
Journal: Science immunology
PubMed ID: 39982976
Doi: 10.1126/sciimmunol.adp5016
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Multivalent S2 subunit vaccines provide broad protection against Clade 1 sarbecoviruses in female mice
Authors: Peter J. Halfmann, Raj S. Patel, Kathryn Loeffler, Atsuhiro Yasuhara, Lee-Ann Van De Velde, Jie E. Yang, Jordan Chervin, Chloe Troxell, Min Huang, Naiying Zheng, Elizabeth R. Wright, Paul G. Thomas, Patrick C. Wilson, Yoshihiro Kawaoka & Ravi S. Kane
Journal: Nature Communications
PubMed ID: 39774966
Doi: 10.1038/s41467-025-55824-y
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A high-fidelity CRISPR-Cas13 system improves abnormalities associated with C9ORF72-linked ALS/FTD
Authors: Tristan X. McCallister, Colin K. W. Lim, Mayuri Singh, Sijia Zhang, Najah S. Ahsan, William M. Terpstra, Alisha Y. Xiong, M. Alejandra Zeballos C, Jackson E. Powell, Jenny Drnevich, Yifei Kang & Thomas Gaj
Journal: Nature Communications
PubMed ID: 39779681
Doi: 10.1038/s41467-024-55548-5
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Immunoaffinity Intact Top-Down Mass Spectrometry for Quantification of Neuron-Specific Enolase Gamma, a Low-Abundance Protein Biomarker
Authors: Sebastian A H van den Wildenberg , Sylvia A A M Genet , Maarten A C Broeren , Joost L J van Dongen , Maxime C M van den Oetelaar , Luc Brunsveld , Volkher Scharnhorst , Daan van de Kerkhof
Journal: Anal Chem
PubMed ID: 39710932
Doi: 10.1021/acs.analchem.4c04677
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Compartmentalized Sesquiterpenoid Biosynthesis and Functionalization in the Chlamydomonas reinhardtii Plastid
Authors: Sergio Gutiérrez, Sebastian Overmans, Gordon B. Wellman, Kyle J. Lauersen
Journal: Chemistry Europe
Doi: 10.1002/cbic.202400902
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5′-tRNAGly(GCC) halves generated by IRE1α are linked to the ER stress response
Authors: Hanyong Jin , Ji-Hyun Yeom , Eunkyoung Shin , Yoonjie Ha , Haifeng Liu , Daeyoung Kim , Minju Joo , Yong-Hak Kim , Hak Kyun Kim , Minkyung Ryu, Hong-Man Kim , Jeongkyu Kim , Keun P Kim , Yoonsoo Hahn , Jeehyeon Bae , Kangseok Lee
Journal: Nature Communications
PubMed ID: 39468069
Doi: 10.1038/s41467-024-53624-4
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Orientia tsutsugamushi Ank5 promotes NLRC5 cytoplasmic retention and degradation to inhibit MHC class I expression
Authors: Haley E Adcox , Jason R Hunt , Paige E Allen , Thomas E Siff , Kyle G Rodino , Andrew K Ottens , Jason A Carlyon
Journal: Nature Communications
PubMed ID: 39277599
Doi: 10.1038/s41467-024-52119-6
Products & Services: Custom Vector Construction   Codon Optimization   
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