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Neurogenetic fetal akinesia and arthrogryposis: genetics, expanding genotype-phenotypes and functional genomics
Authors: Ravenscroft G, Clayton JS, Faiz F, Sivadorai P, Milnes D, Cincotta R, Moon P, Kamien B, Edwards M, Delatycki M, Lamont PJ, Chan SH, Colley A, Ma A, Collins F, Hennington L, Zhao T, McGillivray G, Ghedia S, Chao K, O'Donnell-Luria A, Laing NG, Davis MR
Journal: Journal of medical genetics
PubMed ID: 33060286
Doi: 10.1136/jmedgenet-2020-106901
Products & Services: Mutagenesis Services   
Ligand with Two Modes of Interaction with the Dopamine D2 Receptor-An Induced-Fit Mechanism of Insurmountable Antagonism
Authors: Ågren R, Zeberg H, Stępniewski TM, Free RB, Reilly SW, Luedtke RR, Århem P, Ciruela F, Sibley DR, Mach RH, Selent J, Nilsson J, Sahlholm K
Journal: ACS Chemical Neuroscience
PubMed ID: 32865974
Doi: 10.1021/acschemneuro.0c00477
Products & Services: Mutagenesis Services   
The Human-Specific STING Agonist G10 Activates Type I Interferon and the NLRP3 Inflammasome in Porcine Cells
Authors: Sheng-Li Ming, Lei Zeng, Yu-Kun Guo, Shuang Zhang, Guo-Li Li, Ying-Xian Ma, Yun-Yun Zhai, Wen-Ru Chang, Le Yang, Jiang Wang, Guo-Yu Yang, Bei-Bei Chu
Journal: Front Immunol
PubMed ID: 33072119
Doi: 10.3389/fimmu.2020.575818
Products & Services: Mutagenesis Services   Plasmid DNA Preparation   
The Tail of Kinesin-14a in Giardia Is a Dual Regulator of Motility
Authors: Tseng KF,Mickolajczyk KJ,Feng G,Feng Q,Kwok ES,Howe J,Barbar EJ,Dawson SC,Hancock WO,Qiu W
Journal: Current biology : CB
PubMed ID: 32735815
Doi: 10.1016/j.cub.2020.06.090
Products & Services: Mutagenesis Services   
Exploring the molecular determinants for subtypeselectivity of 2‑amino‑1,4,5,6‑ tetrahydropyrimidine‑5‑carboxylic acid analogs as betaine/GABA transporter 1 (BGT1) substrateinhibitors
Authors: Stefanie Kickinger , Anas Al-Khawaja , Anne Stæhr Haugaard , Maria E K Lie , Francesco Bavo , Rebekka Löffler , Maria Damgaard , Gerhard F Ecker , Bente Frølund , Petrine Wellendorph
Journal: Sci Rep
PubMed ID: 32747622
Doi: 10.1038/s41598-020-69908-w
Products & Services: Mutagenesis Services   
Structural Characterization of Sphingomonas sp. KT‑1 PahZ1- Catalyzed Biodegradation of Thermally Synthesized Poly(aspartic acid)
Authors: Chad A. Brambley, Austin L. Bolay, Henry Salvo, Amanda L. Jansch, Tarah J. Yared, Justin M. Miller, Jamie R. Wallen, and Mitch H. Weiland
Journal: sustainable
Doi: 10.1021/acssuschemeng.0c01158
Products & Services: Mutagenesis Services   Gene Synthesis   
Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation
Authors: Bhavika Nagareddy, Arafat Khan, Hyungjin Kim
Journal: J Biol Chem
PubMed ID: 32763975
Doi: 10.1074/jbc.RA120.015288
Products & Services: Catalog Antibody   Mutagenesis Services   GenEZ ORF Clone   
Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody
Authors: Asokan M, Dias J, Liu C, Maximova A, Ernste K, Pegu A, McKee K, Shi W, Chen X, Almasri C, Promsote W, Ambrozak DR, Gama L, Hu J, Douek DC, Todd JP, Lifson JD, Fourati S, Sekaly RP, Crowley AR, Ackerman ME, Ko SH, Kilam D, Boritz EA, Liao LE, Best K, Perelson AS, Mascola JR, Koup RA
Journal: Proceedings of the National Academy of Sciences of the United States of America
PubMed ID: 32690707
Doi: 10.1073/pnas.2008236117
Products & Services: Mutagenesis Services   
Pharmacological Characterization of a Betaine/GABA Transporter 1 (BGT1) Inhibitor Displaying an Unusual Biphasic Inhibition Profile and Anti‑seizure Effects
Authors: Maria E K Lie , Stefanie Kickinger , Jonas Skovgaard-Petersen , Gerhard F Ecker , Rasmus P Clausen , Arne Schousboe , H Steve White , Petrine Wellendorph
Journal: Neurochem Res
PubMed ID: 32248400
Doi: 10.1007/s11064-020-03017-y
Products & Services: Mutagenesis Services   
Mapping the binding site of C1-inhibitor for polyanion cofactors
Authors: Lilian Hor, Jing Pan, James C Whisstock, Robert N Pike, Lakshmi C Wijeyewickrema
Journal: Mol Immunol
PubMed ID: 32717572
Doi: 10.1016/j.molimm.2020.06.018
Products & Services: Mutagenesis Services   

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