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PCR-generated DNA templates enable efficient, rapid, and cost-effective mRNA synthesis

Authors: Naveen Kumar, Nicholas C Hazell, Jiani Bei, Tina Nguyen, Haitao Hu

Journal: Methods

PubMed ID: 40825451

Doi: 10.1016/j.ymeth.2025.08.007

Products & Services: PCR Cloning and Subcloning

Arzanol Inhibits Human Dihydroorotate Dehydrogenase and Shows Antiviral Activity

Authors: Marta Alberti, Martina Tamburello, Stefano Salamone, Giorgio Gallinella, Cinzia Sanna, Giovanni Battista Appendino, Marco L Lolli, Alberto Massarotti, Federica Pollastro, Riccardo Miggiano

Journal: Journal of natural products

PubMed ID: 41143446

Doi: 10.1021/acs.jnatprod.5c00887

Products & Services: PCR Cloning and Subcloning

Structural basis for 3C and 3CD recruitment by enteroviral genomes during negative-strand RNA synthesis

Authors: Naba Krishna Das, Alisha Patel, Reem Abdelghani, Deepak Koirala

Journal: Nature Communications

PubMed ID: 41120315

Doi: doi.org/10.1038/s41467-025-64376-0

Products & Services: Codon Optimization PCR Cloning and Subcloning

Pfs230 Domains 7–10 Encoded by DNA Vaccines Induce Potent Complement-Independent Transmission-Blocking Antibody Against Plasmodium falciparum

Authors: Yi Cao, Clifford T H Hayashi, Abhai K Tripathi, Eizo Takashima, Takafumi Tsuboi, Tucker B Harju, Nirbhay Kumar

Journal: The Journal of infectious diseases

PubMed ID: 41172338

Doi: doi.org/10.1093/infdis/jiaf555

Products & Services: PCR Cloning and Subcloning

Baculovirus-Mediated Gene Therapy: Targeting BIRC6 for Lung and Breast Cancer

Authors: Abril Marchesini, Santiago M Gómez Bergna, Leslie C Amorós Morales, María Florencia López, Larisa Vásquez, Silvana E Tongiani, Florencia González Morán, Víctor Romanowski, María Florencia Gottardo, Matias L Pidre

Journal: Viruses

PubMed ID: 41305480

Doi: 10.3390/v17111458

Products & Services: PCR Cloning and Subcloning Plasmid DNA Preparation

Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

Authors: Shuai Jin, Zixu Zhu, Yunjia Li, Shouyue Zhang, Yijing Liu, Danyuan Li, Yuanqing Li, Yingfeng Luo, Zhiheng Cheng, Kevin Tianmeng Zhao, Qiang Gao, Guanglei Yang, Hongchao Li, Ronghong Liang, Rui Zhang, Jin-Long Qiu, Yong E Zhang, Jun-Jie Gogo Liu, Caixia Gao

Journal: Cell

PubMed ID: 41027434

Doi: doi.org/10.1016/j.cell.2025.09.004

Products & Services: Codon Optimization PCR Cloning and Subcloning

Signal-strapping as a protein-sequence search method for the discovery of metalloproteins

Authors: João Paulo L Franco Cairo, Thamy L R Corrêa, Wendy A Offen, Alison K Nairn, Julia Walton, Sean T Sweeney, Gideon J Davies, Paul H Walton

Journal: Nature Communications

PubMed ID: 41115942

Doi: 10.1038/s41467-025-64309-x

Products & Services: Gene Synthesis PCR Cloning and Subcloning

Provision of a Redox Donor to Oxy-Ferrous PrnB Is Required for Pyrrolnitrin Synthesis

Authors: R Brian McMillan, Hannah E Gering, Anastasia E Ledinina, Shan Xue, Sayali Karandikar, Shuangjun Lin, Garim You, Tzu-Yu Chen, Yisong Guo, Wei-Chen Chang, Thomas M Makris

Journal: Biochemistry

PubMed ID: 40827054

Doi: 10.1021/acs.biochem.5c00263

Products & Services: Gene Synthesis PCR Cloning and Subcloning Codon Optimization

Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious

Authors: Jiří Holoubek, Jiří Salát, Milos Matkovic, Petr Bednář, Pavel Novotný, Martin Hradilek, Taťána Majerová, Ebba Rosendal, Luděk Eyer, Andrea Fořtová, Michaela Beránková, Lesley Bell-Sakyi, Anna K. Överby, Andrea Cavalli, Massimiliano Bonomi, Félix A. Rey, Daniel Růžek

Journal: Nature Communications

PubMed ID: 40796726

Doi: 10.1038/s41467-025-62750-6.

Products & Services: PCR Cloning and Subcloning

E. coli-mediated expedient biosynthesis of biotin-labeled ubiquitin probe enables activity-based profiling of deubiquitinases in cytoplasmic and nuclear compartments

Authors: Shuai Peng, Shaowen Wang, Xiaotong Liu, Hongrui Xu, Guoqiang Xu, Jia-bin Li

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.111760

Products & Services: Codon Optimization Gene Synthesis PCR Cloning and Subcloning