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Myosin-dependent short actin filaments contribute to peripheral widening in developing stereocilia

Authors: Xiayi Liao, Chun-Yu Tung, Jocelyn F Krey, Ghazaleh Behnammanesh, Joseph A Cirilo Jr, Mert Colpan, Christopher M Yengo, Peter G Barr-Gillespie, Jonathan E Bird, Benjamin J Perrin

Journal: Nature Communications

PubMed ID: 40593742

Doi: 10.1038/s41467-025-60976-y

Products & Services: Gene Synthesis

Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system

Authors: Fanjun Li , Amogh Kumar Baranwal , Sebastian J Maerkl

Journal: Nature Communications

PubMed ID: 40617857

Doi: 10.1038/s41467-025-61671-8

Products & Services: Gene Synthesis

Human Schlafen 14 Cleavage of Short Double-Stranded RNAs Underpins its Antiviral Activity

Authors: Mengyun Li, Dapeng Sun, Wei Hao, Hua Fu, Yueli Zhang, Zhijian Li, Bo Qin, Yumei Wang, Sheng Cui

Journal: Advanced Science

PubMed ID: 40642785

Doi: 10.1002/advs.202501727

Products & Services: Gene Synthesis

Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout

Authors: Ludmila A Kasatkina, Chenshuo Ma, Huaxin Sheng, Matthew Lowerison, Luca Menozzi, Mikhail Baloban, Yuqi Tang, Yirui Xu, Lucas Humayun, Tri Vu, Pengfei Song, Junjie Yao, Vladislav V Verkhusha

Journal: Nature Communications

PubMed ID: 40659617

Doi: 10.1038/s41467-025-61532-4

Products & Services: Gene Synthesis

PPP2R1A mutations portend improved survival after cancer immunotherapy

Authors: Yibo Dai, Anne Knisely, Mitsutake Yano, Minghao Dang, Emily M Hinchcliff, Sanghoon Lee, Annalyn Welp, Manoj Chelvanambi, Matthew Lastrapes, Heng Liu, Zhe Yuan, Chen Wang, Hao Nie, Stephanie Jean, Luis J Montaner, Jiakai Hou, Ami Patel, Shrina Patel, Bryan Fellman, Ying Yuan, Baohua Sun, Renganayaki Krishna Pandurengan, Edwin Roger Parra Cuentas, Joseph Celestino, Yan Liu, Jinsong Liu, R Tyler Hillman, Shannon N Westin, Anil K Sood, Pamela T Soliman, Aaron Shafer, Larissa A Meyer, David M Gershenson, David Vining, Dhakshinamoorthy Ganeshan, Karen Lu, Jennifer A Wargo, Weiyi Peng, Rugang Zhang, Linghua Wang, Amir A Jazaeri

Journal: Nature

PubMed ID: 40604275

Doi: 10.1038/s41586-025-09203-8

Products & Services: Gene Synthesis

HIV-1 vif mediates ubiquitination of the proximal protomer in the APOBEC3H dimer to induce degradation

Authors: Katarzyna A Skorupka, Kazuhiro Matsuoka, Bakar Hassan, Rodolfo Ghirlando, Vanivilasini Balachandran, Ting-Hua Chen, Kylie J Walters, Celia A Schiffer, Matthias Wolf, Yasumasa Iwatani, Hiroshi Matsuo

Journal: Nature Communications

PubMed ID: 40593686

Doi: 10.1038/s41467-025-60984-y

Products & Services: Gene Synthesis

Optimizing a human monoclonal antibody for better neutralization of SARS-CoV-2

Authors: Qian Wang, Yicheng Guo, Ryan G Casner, Jian Yu, Manoj S Nair, Jerren Ho, Eswar R Reddem, Ian A Mellis, Madeline Wu, Chih-Chen Tzang, Hsiang Hong, Yaoxing Huang, Lawrence Shapiro, Lihong Liu, David D Ho

Journal: Nature Communications

PubMed ID: 40615407

Doi: 10.1038/s41467-025-61472-z

Products & Services: Gene Synthesis

Primate retroelement exonization and sexually dimorphic IL13RA1 transcription tune type 2 immune responses

Authors: Tobias Plowman, Tom Hofland, Callum Hall, Rachael Thompson, Judith Pape, Kevin W Ng, Laura Doglio, George Kassiotis

Journal: SCIENCE ADVANCES

PubMed ID: 40614216

Doi: 10.1126/sciimmunol.adr1105

Products & Services: Gene Synthesis

Systematic comparison and base-editing-mediated directed protein evolution and functional screening yield superior auxin-inducible degron technology

Authors: De Xing, Tao Bai, Ozlem Neyisci, Seyedeh Zahra Paylakhi, Alexander J Duval, Yasemin Tekin, Mazhar Adli

Journal: Nature Communications

PubMed ID: 40681502

Doi: 10.1038/s41467-025-61848-1

Products & Services: Gene Synthesis

Non-antibiotics disrupt colonization resistance against enteropathogens

Authors: Anne Grießhammer, Jacobo de la Cuesta-Zuluaga, Patrick Müller, Cordula Gekeler, Jan Homolak, Hsuan Chang, Katharina Schmitt, Chiara Planker, Verena Schmidtchen, Suchira Gallage, Erwin Bohn, Taylor H Nguyen, Jenny Hetzer, Mathias Heikenwälder, Kerwyn Casey Huang, Taiyeb Zahir, Lisa Maier

Journal: Nature

PubMed ID: 40670795

Doi: 10.1038/s41586-025-09217-2

Products & Services: Gene Synthesis