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Chemically modified tRNA enhances the translation capacity of mRNA rich in cognate codons

Authors: Liangzhen Dong, Jiayu Wang, Qing Xia

Journal: Nature Communications

PubMed ID: 40846860

Doi: 10.1038/s41467-025-62981-7.

Products & Services: Gene Synthesis

Optimization of Multiple Combinations of Early Secretion Pathways to Enhance Extracellular Protein Secretion in Komagataella phaffii

Authors: Hai Xu, Shijie Wang, Kang Li, Zhonghu Bai, Yankun Yang

Journal: Journal of Agricultural and Food Chemistry

PubMed ID: 40616507

Doi: doi.org/10.1021/acs.jafc.5c03402

Products & Services: Gene Synthesis

CD19-ReTARGTPR: A Novel Fusion Protein for Physiological Engagement of Anti-CMV Cytotoxic T Cells Against CD19-Expressing Malignancies

Authors: Anne Paulien van Wijngaarden, Isabel Britsch, Matthias Peipp, Douwe Freerk Samplonius, Wijnand Helfrich

Journal: Cancers

PubMed ID: 40723184

Products & Services: Gene Synthesis

A Carbamoyl N-Methyltransferase Catalyzes N-Methylation of the Primary Amide in Ansacarbamitocin Biosynthesis

Authors: Zhongyue Li, Wanting Yang, Zhonglin Sun, Haoxin Wang, Chunhua Lu, Deyu Zhu, Yuemao Shen

Journal: Journal of the American Chemical Society

PubMed ID: 40601550

Doi: 10.1021/jacs.5c05398

Products & Services: Gene Synthesis Gene Synthesis

CryoEM structure of the SLFN14 endoribonuclease reveals insight into RNA binding and cleavage

Authors: Justin Van Riper, Arleth O Martinez-Claros, Lie Wang, Hannah E Schneiderman, Sweta Maheshwari, Monica C Pillon

Journal: Nature Communications

PubMed ID: 40592880

Doi: 10.1038/s41467-025-61091-8

Products & Services: Gene Synthesis

Human protein interaction networks of ancestral and variant SARS-CoV-2 in organ-specific cells and bodily fluids

Authors: Kirsten Broderick, Mohamed Taha Moutaoufik, Tatiana Saccon, Ramy Malty, Shahreen Amin, Sadhna Phanse, Thomson Patrick Joseph, Mara Zilocchi, Ali Hosseinnia, Zoe Istace, Maryam Hajikarimlou, Sakib Abrar, Jade Fisher, Raelynn Brassard, Ranawaka Perera, Anil Kumar, Hiroyuki Aoki, Matineh Rahmatbakhsh, Matthew Jessulat, Darwyn Kobasa, Frank Dehne, Bhanu Prasad, Alla Gagarinova, M Joanne Lemieux, Alan Cochrane, Walid A Houry, Khaled A Aly, Ashkan Golshani, Mohan Babu

Journal: Nature Communications

PubMed ID: 40593736

Doi: 10.1038/s41467-025-60949-1

Products & Services: Gene Synthesis

Single-dose avian influenza A(H5N1) Clade 2.3.4.4b hemagglutinin-Matrix-M® nanoparticle vaccine induces neutralizing responses in nonhuman primates

Authors: Nita Patel, Asma Rehman, Jessica F Trost, Rhonda Flores, Zach Longacre, Mimi Guebre-Xabier, Haixia Zhou, Bin Zhou, Kelsey Jacobson, Desheng Jiang, Xiaoyun Bai, Rafia Khatoon, Thomas Kort, James Norton, M Madhangi, Melinda Hersey, Ann M Greene, Filip Dubovsky, Gale Smith

Journal: Nature Communications

PubMed ID: 40681543

Doi: 10.1038/s41467-025-61964-y

Products & Services: Gene Synthesis

Regulation of inflammatory responses by pH-dependent transcriptional condensates

Authors: Zhongyang Wu, Scott D Pope, Nasiha S Ahmed, Diana L Leung, Yu Hong, Stephanie Hajjar, Cathleen Krabak, Zhe Zhong, Krishnan Raghunathan, Qiuyu Yue, Diya M Anand, Elizabeth B Kopp, Daniel Okin, Weiyi Ma, Ivan Zanoni, Jonathan C Kagan, Jay R Thiagarajah, Diana C Hargreaves, Ruslan Medzhitov, Xu Zhou

Journal: Cell

PubMed ID: 40680734

Doi: 10.1016/j.cell.2025.06.033

Products & Services: Gene Synthesis

Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics

Authors: M Alejandra Tortorici, Annette Choi, Cecily A Gibson, Jimin Lee, Jack T Brown, Cameron Stewart, Anshu Joshi, Sheri Harari, Isabelle Willoughby, Catherine Treichel, Elizabeth M Leaf, Jesse D Bloom, Neil P King, Christine Tait-Burkard, Gary R Whittaker, David Veesler

Journal: Nature

PubMed ID: 40634609

Doi: 10.1038/s41586-025-09155-z

Products & Services: Gene Synthesis

Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system

Authors: Fanjun Li , Amogh Kumar Baranwal , Sebastian J Maerkl

Journal: Nature Communications

PubMed ID: 40617857

Doi: 10.1038/s41467-025-61671-8

Products & Services: Gene Synthesis