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Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

Authors: Taniya Bhardwaj, Kundlik Gadhave, Shivani K Kapuganti, ProfilePrateek Kumar, ProfileZacharias Faidon Brotzakis, Kumar Udit Saumya, Namyashree Nayak, Ankur Kumar, Neha Garg, Michele Vendruscolo, ProfileRajanish Giri

Journal: biorxiv

Doi: doi.org/10.1101/2021.05.29.446267

Products & Services: Peptide Synthesis

A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke

Authors: Sara Ayuso-Dolado, Gema M Esteban-Ortega, Óscar G Vidaurre, Margarita Díaz-Guerra

Journal: Theranostics.

PubMed ID: 34093851

Doi: 10.7150/thno.60701

Products & Services: Peptide Synthesis

A hindbrain dopaminergic neural circuit prevents weight gain by reinforcing food satiation

Authors: Yong Han, Guobin Xia, Yanlin He, Yang He, Monica Farias, Yong Xu, Qi Wu

Journal: Sci Adv

PubMed ID: 34039606

Doi: 10.1126/sciadv.abf8719

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Yeast Bromodomain Factor 1 and Its Human Homolog TAF1 Play Conserved Roles in Promoting Homologous Recombination

Authors: Haoyang Peng, Simin Zhang, Yihan Peng, Shuangyi Zhu, Xin Zhao, Xiaocong Zhao, Shuangshuang Yang, Guangxue Liu, Yang Dong, Xiaoli Gan, Qing Li, Xinghua Zhang, Huadong Pei, Xuefeng Chen

Journal: Adv Sci (Weinh)

PubMed ID: 34056863

Doi: 10.1002/advs.202100753

Products & Services: Peptide Synthesis

Probing the binding of interleukin-23 to individual receptor components and the IL-23 heteromeric receptor complex in living cells using NanoBRET

Authors: Charles S Lay, Angela Bridges, Joelle Goulding, Stephen J Briddon, Zoja Soloviev, Peter D Craggs, Stephen J Hill

Journal: Cell Chem Biol

PubMed ID: 34038748

Doi: 10.1016/j.chembiol.2021.05.002

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Robust α-synuclein pathology in select brainstem neuronal populations is a potential instigator of multiple system atrophy

Authors: Ethan W Hass, Zachary A Sorrentino, Grace M Lloyd, Nikolaus R McFarland, Stefan Prokop, Benoit I Giasson

Journal: Acta Neuropathol Commun

PubMed ID: 33941284

Doi: 10.1186/s40478-021-01173-y

Products & Services: Peptide Synthesis

Elastin-like polypeptide and γ-zein fusions significantly increase recombinant protein accumulation in soybean seeds

Authors: Jing Yang, HongWei Xun, Lu Niu, Hongli He, Yunqing Cheng, Xiaofang Zhong, Qianqian Zhao, Guojie Xing, Jianfeng Liu, Xiangdong Yang

Journal: Transgenic Res

PubMed ID: 33963986

Doi: 10.1007/s11248-021-00258-7

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Recombinant human Erythropoietin enhanced the cytotoxic effects of tamoxifen toward the spheroid MCF-7 breast cancer cells

Authors: Hareth Y Shujaa Edin, Nagi A Al-Haj, Abdullah Rasedee, Noorjahan Banu Alitheen, Arifah Abdul Kadir, Chee Wun How, Heshu Sulaiman Rahman, Hussah Abdullah Al-Shwyeh

Journal: Saudi J Biol Sci

PubMed ID: 34466099

Doi: 10.1016/j.sjbs.2021.05.043

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Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Authors: Kevin O Saunders, Esther Lee, Robert Parks, David R Martinez, Dapeng Li, Haiyan Chen, Robert J Edwards, Sophie Gobeil, Maggie Barr, Katayoun Mansouri, S Munir Alam, Laura L Sutherland, Fangping Cai, Aja M Sanzone, Madison Berry, Kartik Manne, Kevin W Bock, Mahnaz Minai, Bianca M Nagata, Anyway B Kapingidza, Mihai Azoitei, Longping V Tse, Trevor D Scobey, Rachel L Spreng, R Wes Rountree, C Todd DeMarco, Thomas N Denny, Christopher W Woods, Elizabeth W Petzold, Juanjie Tang, Thomas H Oguin, Gregory D Sempowski, Matthew Gagne, Daniel C Douek, Mark A Tomai, Christopher B Fox, Robert Seder, Kevin Wiehe, Drew Weissman, Norbert Pardi, Hana Golding, Surender Khurana, Priyamvada Acharya, Hanne Andersen, Mark G Lewis, Ian N Moore, David C Montefiori, Ralph S Baric, Barton F Haynes

Journal: Nature

PubMed ID: 33971664

Doi: 10.1038/s41586-021-03594-0

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Human diamine oxidase cellular binding and internalization in vitro and rapid clearance in vivo are not mediated by N-glycans but by heparan sulfate proteoglycan interactions.

Authors: Gludovacz E,Schuetzenberger K,Resch M,Tillmann K,Petroczi K,Vondra S,Vakal S,Schosserer M,Virgolini N,Pollheimer J,Salminen TA,Jilma B,Borth N,Boehm T

Journal: Glycobiology

PubMed ID: 32985651

Doi: 10.1093/glycob/cwaa090

Products & Services: Peptide Synthesis