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The MBNL3 splicing factor promotes hepatocellular carcinoma by increasing PXN expression through the alternative splicing of lncRNA-PXN-AS1

Authors: Ji-hangYuan,Xiao-ningLiu,Tian-tianWang,WeiPan,Qi-feiTao,Wei-pingZhou,FangWang andShu-hanSun

Journal: Nature Cell Biology

Doi: 10.1038/ncb3538

Products & Services: Peptide Synthesis

Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease

Authors: Deborah Doens, Pedro Alberto Valiente, Adelphe M. Mfuh, Anh X. T. Vo, Adilia Tristan, Lizmar Carreño, Mario Quijada, Vu T. Nguyen, George Perry, Oleg V. Larionov, Ricardo Lleonart, and Patricia L. Fernandez

Journal: ACS Chemical

Doi: 10.1021/acschemneuro.6b00386

Products & Services: Peptide Synthesis

Acquisition of C1 inhibitor by Bordetella pertussis virulence associated gene 8 results in C2 and C4 consumption away from the bacterial surface

Authors: Elise S. Hovingh, Bryan van den Broek, Betsy Kuipers, Elena Pinelli, Suzan H. M. Rooijakkers, Ilse Jongerius

Journal: PLOS Pathogens

Doi: 10.1371/journal.ppat.1006531

Products & Services: Peptide Synthesis

Enhanced class I tumor antigen presentation via cytosolic delivery of exosomal cargos by tumor-cell-derived exosomes displaying a pH-sensitive fusogenic peptide

Authors: Hiroaki Ishida, KatharineV. Jensen, AndrewG.Woodman, M. Eric Hyndman & Hans J.Voge

Journal: Scientific REPORTS

Doi: 10.1038/srep40662

Products & Services: Peptide Synthesis

ThiN as a versatile domain of transcriptional repressors and catalytic enzymes of thiamine biosynthesis

Authors: antigens Ziwei Xiao, Zhiyong Ye, Vikeramjeet Singh Tadwal, Meixin Shen & Ee Chee Ren

Journal: Scientific Reports,

Doi: 10.1038/s41598-017-05171-w

Products & Services: Peptide Synthesis

Quantitative mapping of the spatial distribution of nanoparticles in endo-lysosomes by local pH

Authors: Ching-Wen Huang Wen-Chin Huang, Xuefeng Qiu, Flavia Fernandes Ferreira da Silva, Aijun Wang , Shyam Patel, Leon J. Nesti, Mu-Ming Poo & Song Li

Journal: Scientific Reports,

Doi: 10.1038/s41598-017-17043

Products & Services: Peptide Synthesis

Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity

Authors: Regina S. Salvata , Deeptak Vermab , Andrew S. Parkerb , Jack R. Kirscha , Seth A. Brooksa,c, Chris Bailey-Kelloggb,d,e,, and Karl E. Griswolda,d,e,f,

Journal: PNAS Early Edition

Doi: 10.1073/pnas.1621233114

Products & Services: Peptide Synthesis

An essential role of high-molecular-weight kininogen in endotoxemia

Authors: Aizhen Yang, * Zhanli Xie, * Bo Wang, * Robert W. Colman, Jihong Dai,, and Yi Wu,

Journal: J. Exp. Med.

Doi: 10.1084/jem.20161900

Products & Services: Peptide Synthesis

Protein Expression and Purification of the Hsp90-Cdc37-Cdk4 Kinase Complex from Saccharomyces cerevisiae.

Authors: Verba KA, Agard DA.

Journal: Bio Protoc

PubMed ID: 29104897

Doi: 10.21769/BioProtoc.2563

Products & Services: Peptide Synthesis

Structural Optimization and Pharmacological Evaluation of Inhibitors Targeting Dual-Specificity Tyrosine Phosphorylation-Regulated Kinases (DYRK) and CDC-like kinases (CLK) in Glioblastoma.

Authors: Zhou Q, Phoa AF, Abbassi RH, Hoque M, Reekie TA, Font JS, Ryan RM, Stringer BW, Day BW, Johns TG, Munoz L, Kassiou M.

Journal: J Med Chem

PubMed ID: 28206758

Doi: 10.1021/acs.jmedchem.6b01840

Products & Services: Peptide Synthesis