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Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain.

Authors: François-Moutal L, Dustrude ET, Wang Y, Brustovetsky T, Dorame A, Ju W, Moutal A, Perez-Miller S, Brustovetsky N, Gokhale V, Khanna M, Khanna R.

Journal: Pain.

PubMed ID: 29847471

Doi: 10.1097/j.pain.0000000000001294

Products & Services: Peptide Synthesis

Targeting F2R/PAR1 with ligand decorated lipid nanocarriers for enhanced drug delivery into ovarian cancer cells

Authors: Riya Khetan; Weranga Rajapaksha; Bukuru D. Nturubika; Todd A. Gillam; Doug A. Brooks; Sanjay Garg; Anton Blencowe; Hugo Albrecht; Preethi Eldi

Journal: Frontiers in Drug Delivery

PubMed ID: 41608127

Doi: 10.3389/fddev.2025.1727958

Products & Services: Peptide Synthesis

Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers.

Authors: NguyenTrung T，DingDerong，WolterWilliam R，ChampionMatthew M，HesekDusan，LeeMijoon，PérezRocio L，SchroederValerie A，SuckowMark A，MobasheryShahriar，ChangMay

Journal: Eur. J. Pharmacol.

PubMed ID: 30012502

Doi: 10.1016/j.ejphar.2018.07.014

Products & Services: Peptide Synthesis

An accelerated， clinical-grade protocol to generate high yields of type 1-polarizing messenger RNA-loaded dendritic cells for cancer vaccination.

Authors: BrabantsE，HeynsK，SmetS DE，DevrekerP，IngelsJ，CabooterN DE，DebackerV，DullaersM，VAN MeerbeeckJ P，VandekerckhoveB，Vermaele

Journal: Cytotherapy

PubMed ID: 30122654

Doi: 10.1016/j.jcyt.2018.06.006

Products & Services: Peptide Synthesis

Identification and immunogenic evaluation of T cell epitopes based on tembusu virus envelope protein in ducks.

Authors: ZhaoDongmin，HanKaikai，ZhangLijiao，WangHuili，TianYujie，HuangXinmei，LiuQingtao，YangJing，LiuYuzhuo，L

Journal: Virus Res.

PubMed ID: 30240806

Doi: 10.1016/j.virusres.2018.09.008

Products & Services: Peptide Synthesis

Biological Profiling of Coleoptericins and Coleoptericin-Like Antimicrobial Peptides from the Invasive Harlequin Ladybird Harmonia axyridis.

Authors: HirschRolf，WiesnerJochen，MarkerAlexander，BauerArmin，HammannPeter E，VilcinskasAnd

Journal: Adv. Exp. Med. Biol.

PubMed ID: 30269257

Doi: 10.1007/5584_2018_276

Products & Services: Peptide Synthesis

Asiatic acid protects differentiated PC12 cells from Aβ-induced apoptosis and tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β signaling.

Authors: ChengWenjing，ChenWeimei，WangPeng，ChuJian

Journal: Life Sci.

PubMed ID: 30017668

Doi: 10.1016/j.lfs.2018.07.016

Products & Services: Peptide Synthesis

Specificity profiling of human trypsin-isoenzymes

Authors: Schilling O, Biniossek ML, Mayer B, Elsässer B, Brandstetter H, Goettig P, Stenman UH, Koistinen H.

Journal: Biol Chem.

PubMed ID: 29883318

Doi: 10.1515/hsz-2018-0107.

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Analytical and clinical validation of a high accuracy fully automated digital immunoassay for plasma phospho-Tau 217 for clinical use in detecting amyloid pathology

Authors: David Wilson; Meenakshi Khare; Gallen Triana-Baltzer; Michele Wolfe; Patrick Sheehy; Karen Copeland; Lyndal Hesterberg; Ann-Jeanette Vasko; Wiesje M. van der Flier; Inge M. W. Verberk; Charlotte E. Teunissen; Mike Miller

Journal: Frontiers in Neurology

PubMed ID: 40708958

Doi: 10.3389/fneur.2025.1568971

Products & Services: Peptide Synthesis

Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain

Authors: Yang YM, Arsenault J, Bah A, Krzeminski M, Fekete A, Chao OY, Pacey LK, Wang A, Forman-Kay J, Hampson DR, Wang LY

Journal: Mol Psychiatry

PubMed ID: 30224722

Doi: 10.1038/s41380-018-0240-0

Products & Services: Peptide Synthesis Gene Synthesis