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Engineered botulinum neurotoxin B with improved binding to human receptors has enhanced efficacy in preclinical models.

Authors: ElliottMark，Favre-GuilmardChristine，LiuSai Man，MaignelJacquie，MasuyerGeoffrey，BeardMatthew，BooneChristopher，CarréDenis，KalinichevMikhail，LezmiStephane，MirImran，NicoleauCamille，PalanShilpa，PerierCindy，RabanElsa，ZhangSicai，DongMin，StenmarkPål，KruppJoha

Journal: Sci Adv

PubMed ID: 30746458

Doi: 10.1126/sciadv.aau7196

Products & Services: Peptide Synthesis

Peptide-grafted dextran vectors for efficient and high-loading gene delivery.

Authors: HuYang，WangHuifeng，SongHaiqing，YoungMegan，FanYaqian，XuFu-Jian，QuXinjian，LeiXia，LiuYing，Cheng

Journal: Biomater Sci

PubMed ID: 30681086

Doi: 10.1039/c8bm01341a

Products & Services: Peptide Synthesis

The helix-to-sheet transition of an HIV-1 fusion peptide derivative changes the mechanical properties of lipid bilayer membranes.

Authors: HellerWilliam T，ZolnierczukPio

Journal: Biochim Biophys Acta Biomembr

PubMed ID: 30550881

Doi: 10.1016/j.bbamem.2018.12.004

Products & Services: Peptide Synthesis

Dendritic Cell Membrane Vesicles for Activation and Maintenance of Antigen-Specific T Cells.

Authors: OchylLukasz J，MoonJam

Journal: Adv Healthc Mater

PubMed ID: 30565895

Doi: 10.1002/adhm.201801091

Products & Services: Peptide Synthesis

The C-terminal SAM domain of p73 binds to the N terminus of MDM2.

Authors: NeiraJosé L，Díaz-GarcíaClara，PrietoManuel，Coutinh

Journal: Biochim Biophys Acta Gen Subj

PubMed ID: 30735716

Doi: 10.1016/j.bbagen.2019.01.019

Products & Services: Peptide Synthesis

Automated Gait Analysis Detects Improvements after Intracellular σ Peptide Administration in a Rat Hemisection Model of Spinal Cord Injury.

Authors: HamTrevor R，FarragMahmoud，SoltiszAndrew M，LakesEmily H，AllenKyle D，LeipzigN

Journal: Ann Biomed Eng

PubMed ID: 30627839

Doi: 10.1007/s10439-019-02198-0

Products & Services: Peptide Synthesis

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions.

Authors: CastellaMaria，BoronatAnna，Martín-IbáñezRaquel，RodríguezVanina，SuñéGuillermo，CaballeroMiguel，MarzalBerta，Pérez-AmillLorena，Martín-AntonioBeatriz，CastañoJulio，BuenoClara，BalaguéOlga，González-NavarroEuropa Azucena，Serra-PagesCarles，EngelPablo，VilellaRamon，Benitez-RibasDaniel，Ortiz-MaldonadoValentín，CidJoan，TaberaJaime，CanalsJosep M，LozanoMiquel，BaumannTycho，VilarrodonaAnna，TriasEsteve，CampoElías，MenendezPablo，Urbano-IspizuaÁlvaro，YagüeJordi，Pérez-GalánPatricia，RivesSusana，DelgadoJulio，JuanM

Journal: Mol Ther Methods Clin Dev

PubMed ID: 30623002

Doi: 10.1016/j.omtm.2018.11.010

Products & Services: Peptide Synthesis

New epitopes in ovalbumin provide insights for cancer neoepitopes.

Authors: KarandikarSukrut Hemant，SidneyJohn，SetteAlessandro，SelbyMark Joseph，KormanAlan Jerry，SrivastavaPramod K

Journal: JCI Insight

PubMed ID: 30869653

Doi: 10.1172/jci.insight.127882

Products & Services: Peptide Synthesis

C23， an oligopeptide derived from cold-inducible RNA-binding protein， suppresses inflammation and reduces lung injury in neonatal sepsis.

Authors: DenningNaomi-Liza，YangWeng-Lang，HansenLaura，PrinceJose，Wang

Journal: J. Pediatr. Surg.

PubMed ID: 30691879

Doi: 10.1016/j.jpedsurg.2018.12.020

Products & Services: Peptide Synthesis

Elabela protects against podocyte injury in mice with streptozocin-induced diabetes by associating with the PI3K/Akt/mTOR pathway.

Authors: Zhang Y, Wang Y, Luo M, Xu F, Lu Y, Zhou X, Cui W, Miao L.

Journal: Peptides

PubMed ID: 30959144

Doi: 10.1016/j.peptides.2019.04.005

Products & Services: Peptide Synthesis