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Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch.

Authors: MeixiongJames，AndersonMichael，LimjunyawongNathachit，SabbaghMark F，HuEric，MackMadison R，OetjenLandon K，WangFang，KimBrian S，DongXinz

Journal: Immunity

PubMed ID: 31027996

Doi: 10.1016/j.immuni.2019.03.013

Products & Services: Peptide Synthesis

Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer.

Authors: ZouLing-Jiao，XiangQiu-Ping，XueXiao-Qian，ZhangCheng，LiChen-Chang，WangChao，LiQiu，WangRui，WuShuang，ZhouYu-Lai，ZhangYan，Xu

Journal: Acta Pharmacol. Sin.

PubMed ID: 31097763

Doi: 10.1038/s41401-019-0237-5

Products & Services: Peptide Synthesis

Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer.

Authors: LoWinifred，ParkhurstMaria，RobbinsPaul F，TranEric，LuYong-Chen，JiaLi，GartnerJared J，PasettoAnna，DenigerDrew，MalekzadehParisa，SheltonThomas E，PrickettTodd，RaySatyajit，KivitzScott，PariaBiman C，KrileyIsaac，SchrumpDavid S，RosenbergStev

Journal: Cancer Immunol Res

PubMed ID: 30709841

Doi: 10.1158/2326-6066.CIR-18-0686

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Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration.

Authors: LuoLing，ZhangXiaohui，HiranoYoshio，TyagiPuneet，BarabásPéter，UeharaHironori，MiyaTadashi R，SinghNirbhai，ArcherBonnie，QaziYureeda，JackmanKyle，DasSubrata K，OlsenThomas，ChennamaneniSrinivas R，StaggBrian C，AhmedFaisal，EmersonLyska，ZygmuntKristen，WhitakerRoss，MamalisChristina，HuangWei，GaoGuangping，SrinivasSangly P，KrizajDavid，BaffiJudit，AmbatiJayakrishna，KompellaUday B，AmbatiBalamura

Journal: ACS Nano

PubMed ID: 23464925

Doi: 10.1021/nn305958y

Products & Services: Peptide Synthesis

FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates.

Authors: TurcoEleonora，WittMarie，AbertChristine，Bock-BierbaumTobias，SuMing-Yuan，TrapannoneRiccardo，SztachoMartin，DanieliAlberto，ShiXiaoshan，ZaffagniniGabriele，GamperAnnamaria，SchuschnigMartina，FracchiollaDorotea，BernklauDaniel，RomanovJulia，HartlMarkus，HurleyJames H，DaumkeOliver，MartensSa

Journal: Mol. Cell

PubMed ID: 30853400

Doi: 10.1016/j.molcel.2019.01.035

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Non-invasive early detection of acute transplant rejection via nanosensors of granzyme B activity.

Authors: MacQuoc D，MathewsDave V，KahlaJustin A，StoffersClaire M，DelmasOlivia M，HoltBrandon Alexander，AdamsAndrew B，KwongGabri

Journal: Nat Biomed Eng

PubMed ID: 30952979

Doi: 10.1038/s41551-019-0358-7

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Nonimmune cell-derived ICOS ligand functions as a renoprotective αvβ3 integrin-selective antagonist.

Authors: KohKwi Hye, CaoYanxia, MangosSteve, TardiNicholas J, DandeRanadheer R, LeeHa Won, SamelkoBeata, AltintasMehmet M, SchmitzVincent P, LeeHyun, MukherjeeKamalika, PeevVasil, CimbalukDavid J, ReiserJochen, HahmEu

Journal: J. Clin. Invest.

PubMed ID: 30747722

Doi: 10.1172/JCI123386

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High-Throughput Three-Dimensional Hydrogel Cell Encapsulation Assay for Measuring Matrix Metalloproteinase Activity

Authors: Fakhouri, A. S., Weist, J. L., Tomusko, A. R., & Leight, J. L.

Journal: ASSAY and Drug Development Technologies

PubMed ID: 30958702

Doi: 10.1089/adt.2018.877

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Anti-HER2 CD4 T-Helper Type 1 Immune Response is Superior to Breast MRI for Assessing Response to Neoadjuvant Therapy in Patients with HER2-Positive Breast Cancer.

Authors: De La CruzLucy M, McDonaldElizabeth S, MickR, DattaJashodeep, NoceraNadia F, XuShuwen, FisherCarla S, CzernieckiBri

Journal: Ann. Surg. Oncol.

PubMed ID: 27826664

Doi: 10.1245/s10434-016-5651-z

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Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy.

Authors: WangJun，SunJingwei，LiuLinda N，FliesDallas B，NieXinxin，TokiMaria，ZhangJianping，SongChang，ZarrMelissa，ZhouXu，HanXue，ArcherKristina A，O'NeillThomas，HerbstRoy S，BotoAgedi N，SanmamedMiguel F，LangermannSolomon，RimmDavid L，ChenLie

Journal: Nat. Med.

PubMed ID: 30833750

Doi: 10.1038/s41591-019-0374-x

Products & Services: Peptide Synthesis