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De Novo Multi Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Authors: Xiaojuan Li; Haifan Gong; Yue Wang; Yinuo Zhao; Lixiang Li; Peijing Bao; Qingzhou Kong; Jialu Fu; Boyao Wan; Yumeng Zhang; Jinghui Zhang; Jiekun Ni; Zhongxue Han; Xueping Nan; Kunping Ju; Longfei Sun; Yuerui Ma; Huijun Chang; Mengqi Zheng; Yanbo Yu; Xiaoyun Yang; Xiuli Zuo; Haina Wang; Yanqing Li
Journal: Advanced Science
PubMed ID: 41801219
Doi: 10.1002/advs.202515835
Products & Services: Peptide Synthesis   
Human skeletal development and regeneration are shaped by functional diversity of stem cells across skeletal sites
Authors: Thomas H Ambrosi, Sahar Taheri, Kun Chen, Rahul Sinha, Yuting Wang, Ethan J Hunt, L Henry Goodnough, Matthew P Murphy, Holly M Steininger, Malachia Y Hoover, Franco Felix, Kelly C Weldon, Lauren S Koepke, Jan Sokol, Daniel Dan Liu, Liming Zhao, Stephanie D Conley, Wan-Jin Lu, Maurizio Morri, Norma F Neff, Noelle L Van Rysselberghe, Erika E Wheeler, Yongheng Wang, J Kent Leach, Augustine Saiz, Aijun Wang, George P Yang, Stuart Goodman, Julius A Bishop, Michael J Gardner, Derrick C Wan, Irving L Weissman, Michael T Longaker, Debashis Sahoo, Charles K F Chan
Journal: Cell Stem Cell
PubMed ID: 40118065
Doi: 10.1016/j.stem.2025.02.013
Products & Services: Peptide Synthesis   
Design, synthesis, and mechanism study of dimerized phenylalanine derivatives as novel HIV-1 capsid inhibitors
Authors: Xujie Zhang; Lin Sun; Megan E. Meuser; Waleed A. Zalloum; Shujing Xu; Tianguang Huang; Srinivasulu Cherukupalli; Xiangyi Jiang; Xiao Ding; Yucen Tao; Dongwei Kang; Erik De Clercq; Christophe Pannecouque; Alexej Dick; Simon Cocklin; Xinyong Liu; Peng Zhan
Journal: European Journal of Medicinal Chemistry
PubMed ID: 34592608
Doi: 10.1016/j.ejmech.2021.113848
Products & Services: Peptide Synthesis   
De Novo Multi Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Authors: Xiaojuan Li; Haifan Gong; Yue Wang; Yinuo Zhao; Lixiang Li; Peijing Bao; Qingzhou Kong; Jialu Fu; Boyao Wan; Yumeng Zhang; Jinghui Zhang; Jiekun Ni; Zhongxue Han; Xueping Nan; Kunping Ju; Longfei Sun; Yuerui Ma; Huijun Chang; Mengqi Zheng; Yanbo Yu; Xiaoyun Yang; Xiuli Zuo; Haina Wang; Yanqing Li
Journal: Advanced Science
PubMed ID: 41801219
Doi: 10.1002/advs.202515835
Products & Services: Peptide Synthesis   
Novel Bivalent mRNA-LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Authors: Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan-Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar-Haim, Orit Redy-Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud
Journal: Advanced Science
PubMed ID: 40279638
Doi: 10.1002/advs.202501286
Products & Services: Peptide Synthesis   
Macrophages direct location-dependent recall of B cell memory to vaccination
Authors: Rama Dhenni, Alexandra Carey Hoppé, Arnold Reynaldi, Wunna Kyaw, Nathalie Tricia Handoko, Abigail K. Grootveld, Yuki Honda Keith, Nayan Deger Bhattacharyya, Holly I. Ahel, Aiden Josiah Telfser, Andrew N. McCorkindale, Seyhan Yazar, Christina H.T. Bui, James T. Smith, Weng Hua Khoo, Mollie Boyd, Solange Obeid, Brad Milner, Mitchell Starr, Fabienne Brilot, Tri Giang Phan
Journal: Molecular Therapy
Doi: 10.1016/j.cell.2025.04.005
Products & Services: Peptide Synthesis   
N-Terminal random curl-tandam α-helical peptide 7W: A potent antibacterial and anti-inflammatory dual-effect agent through tryptophan substitution
Authors: Jietao Lou, Xinyi Wu, Wenwen Ji, Jiaye Yu, Yanyan Xu, Wanyang Xiao, Weijie Lu, Kaiyun Xin, Tianbao Chen, Qidong Tang, Guang Liang, Yitian Gao, Di Wu
Journal: Eur J Med Chem
PubMed ID: 40319576
Doi: 10.1016/j.ejmech.2025.117686
Products & Services: Peptide Synthesis   
PIN1-SUMO2/3 motif suppresses excessive RNF168 chromatin accumulation and ubiquitin signaling to promote IR resistance
Authors: Anoop S Chauhan, Matthew J W Mackintosh, Joseph Cassar, Alexander J Lanz, Mohammed Jamshad, Hannah L Mackay, Alexander J Garvin, Alexandra K Walker, Satpal S Jhujh, Teresa Carlomagno, Aneika C Leney, Grant S Stewart, Joanna R Morris
Journal: nature COMMUNICATION
PubMed ID: 40229270
Doi: 10.1038/s41467-025-56974-9
Products & Services: Peptide Synthesis   Monoclonal Antibody Services   
A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication
Authors: Martina Tuttolomondo; Stephanie Thuy Duong Pham; Mikkel Green Terp; Virginia Cend n Castillo; Nazmie Kalisi; Stefan Vogel; Niels Langkj r; Ulla Melchior Hansen; Helge Thisgaard; Henrik Daa Schr der; Yaseelan Palarasah; Henrik J rn Ditzel
Journal: Molecular therapy. Nucleic acids
PubMed ID: 38939051
Doi: 10.1016/j.omtn.2024.102227
Products & Services: Peptide Synthesis   
A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replication
Authors: Martina Tuttolomondo; Stephanie Thuy Duong Pham; Mikkel Green Terp; Virginia Cend n Castillo; Nazmie Kalisi; Stefan Vogel; Niels Langkj r; Ulla Melchior Hansen; Helge Thisgaard; Henrik Daa Schr der; Yaseelan Palarasah; Henrik J rn Ditzel
Journal: Molecular therapy. Nucleic acids
PubMed ID: 38939051
Doi: 10.1016/j.omtn.2024.102227
Products & Services: Peptide Synthesis   
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