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The isolated La-module of LARP1 mediates 3' poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1

Authors: Mattijssen S, Kozlov G, Gaidamakov S, Ran01 A, Fonseca BD, Gehring K, Maraia RJ

Journal: RNA biology

PubMed ID: 33292040

Doi: 10.1080/15476286.2020.1860376

Products & Services: Peptide Synthesis

Neuromodulation Can Be Simple: Myoinhibitory Peptide, Contained in Dedicated Regulatory Pathways, Is the Only Neurally-Mediated Peptide Modulator of Stick Insect Leg Muscle

Authors: Sander Liessem, Daniel Kowatschew, Stefan Dippel, Alexander Blanke, Sigrun Korsching, Christoph Guschlbauer, Scott L Hooper, Reinhard Predel, Ansgar Büschges

Journal: J Neurosci

PubMed ID: 33531417

Doi: 10.1523/JNEUROSCI.0188-20.2021

Products & Services: Peptide Synthesis

Spent Hen Muscle Protein-Derived RAS Regulating Peptides Show Antioxidant Activity in Vascular Cells

Authors: Hongbing Fan, Khushwant S Bhullar, Jianping Wu

Journal: Antioxidants (Basel)

PubMed ID: 33671990

Doi: 10.3390/antiox10020290

Products & Services: Peptide Synthesis

Amyloid cross-sequence interaction between Aβ(1-40) and αA(66-80) in relation to the pathogenesis of cataract

Authors: Anna Schimansky, Jay Kant Yadav

Journal: Int J Biol Macromol

PubMed ID: 33626371

Doi: 10.1016/j.ijbiomac.2021.02.111

Products & Services: Peptide Synthesis

Eltrombopag directly inhibits BAX and prevents cell death

Authors: Adam Z Spitz, Emmanouil Zacharioudakis, Denis E Reyna, Thomas P Garner, Evripidis Gavathiotis

Journal: Nat Commun

PubMed ID: 33602934

Doi: 10.1038/s41467-021-21224-1

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HPV-Associated Tumor Eradication by Vaccination with Synthetic Short Peptides and Particle-Forming Liposomes

Authors: Xuedan He, Shiqi Zhou, Breandan Quinn, Dushyant Jahagirdar, Joaquin Ortega, Scott I Abrams, Jonathan F Lovell

Journal: Small

PubMed ID: 33605054

Doi: 10.1002/smll.202007165

Products & Services: Peptide Synthesis

Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells

Authors: Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo B Bifulco, Brady Bernard, Rom S Leidner, Brendan D Curti, Bernard A Fox, Walter J Urba, R Bryan Bell, Andrew D Weinberg

Journal: Nat Commun

PubMed ID: 33594075

Doi: 10.1038/s41467-021-21383-1

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Mitochondrial Damage-Associated Molecular Patterns Exacerbate Lung Fluid Imbalance Via the Formyl Peptide Receptor-1 Signaling Pathway in Acute Lung Injury

Authors: Zhi-Cheng Yuan, Ni Zeng, Lian Liu, Tao Wang, Lu-Qi Dai, Hao Wang, Zi-Jian Zeng, Yu-Fang Cao, Yong-Fang Zhou, Dan Xu, Yong-Chun Shen, Fu-Qiang Wen

Journal: Crit Care Med

PubMed ID: 33165026

Doi: 10.1097/CCM.0000000000004732

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Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

Authors: Motohiro Nonaka , Hideaki Mabashi-Asazuma , Donald L Jarvis , Kazuhiko Yamasaki , Tomoya O Akama , Masato Nagaoka , Toshio Sasai , Itsuko Kimura-Takagi , Yoichi Suwa , Takashi Yaegashi , Chun-Teng Huang , Chizuko Nishizawa-Harada , Michiko N Fukuda

Journal: PLoS ONE

PubMed ID: 33406123

Doi: 10.1371/journal.pone.0241157

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Experimental and Computational Observations of Immunogenic Cobalt Porphyrin Lipid Bilayers: Nanodomain-Enhanced Antigen Association

Authors: Jasmin Federizon, Conrard Giresse Tetsassi Feugmo, Wei-Chiao Huang, Xuedan He, Kazutoyo Miura, Aida Razi, Joaquin Ortega, Mikko Karttunen, Jonathan F Lovell

Journal: Pharmaceutics

PubMed ID: 33466686

Doi: 10.3390/pharmaceutics13010098

Products & Services: Peptide Synthesis