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Discovery of a Dual IDO1/TDO Inhibitor That Modulates Enzymatic Activity and IDO1/SHP‑2 Signaling

Authors: Sarah Jane Rezzi, Andrea Butticè, Salvatore Villani, Gaia Lesca, Sofia Rossini, Eleonora Panfili, Daniele Mazzoletti, Elia Bari, Davide Violante, Marta Serafini, Alberto Massarotti, Ciriana Orabona, Maria Teresa Pallotta, Silvio Aprile, Silvia Fallarini, Erika Del Grosso, Rita Maria Concetta Di Martino, Riccardo Miggiano, Tracey Pirali

Journal: Journal of Medicinal Chemistr

PubMed ID: 42483959

Doi: 10.1021/acs.jmedchem.6c00759

Products & Services: Gene Synthesis

Photocatalytic Golgi Proteomics Reveals Palmitoylation-Regulated Golgiphagy

Authors: Yufei Di, Fuhu Guo, Ziqi Liu, Haotian Guo, Linghao Kong, Peng R Chen, Xinyuan Fan

Journal: Journal of the American Chemical Society

PubMed ID: 42619132

Doi: 10.1021/jacs.6c13532

Products & Services: Gene Synthesis

Reprogramming RNA Degraders as Intracellular Molecule Sensors for Tumor Cell Sensing and Manipulation

Authors: Pin-Ru Chen, Ying Han, Pei-Pei Qin, Ying-Yue Xu, Qian Tao, Bang-Ce Ye, Bin-Cheng Yin

Journal: ACS Sensors

PubMed ID: 42681980

Doi: 10.1021/acssensors.6c01983

Products & Services: Gene Synthesis

Description of the rate-limiting hydrogen tunneling mechanism for plant 9- and 13-lipoxygenases

Authors: Alex Kockler, Katherine Ray, Jordan King, Eric Anderson, Joi Walker, Nathaniel Gilbert, Patrick Horn, Adam R Offenbacher

Journal: Protein Science

PubMed ID: 42227275

Doi: 10.1002/pro.70647

Products & Services: Gene Synthesis

Synthetic promoters developed through a site-specific integration system enhance antibody expression in fed-batch culture

Authors: Liyun Yue, Hao Li, Songtao Zhou

Journal: Engineering in Life Sciences

PubMed ID: 42781470

Doi: 10.48130/els-0026-0004

Products & Services: Gene Synthesis

Efficient in vivo cytosine base editing using virus-like particles with uracil DNA glycosylase inhibition

Authors: Junjie Zhu, Lin Ding, Kai-Ming Liu, Xingyu Zhu, Jifang Li, Buer Ha, Bao-Qing Gao, Xujiao Zhou, Chengfang Liu, Jia Wei, Shuangyu Ma, Wenchao Xu, Lingyun Kong, Jing Wu, Xiaodun Mou, Bei Yang, Lijie Wang, Jiaxu Hong, Li Yang & Jia Chen

Journal: Nature Biotechnology

Doi: 10.1038/s41587-026-03227-9

Products & Services: Gene Synthesis Synthetic Guide RNA

Beyond CAT, BSD, and URA: SUL, A novel selectable marker for Cyanidioschyzon merolae

Authors: Yissell Borges-Rodríguez, Martha R Stark, Elise Kerckhofs, Julie Mueller, Kyle J Lauersen, Daniel Schubert, Stephen D Rader

Journal: New biotechnology

PubMed ID: 41643937

Doi: 10.1016/j.nbt.2026.01.012

Products & Services: Gene Synthesis

Viral protease-initiated lytic cell death as a universal antiviral mRNA therapy

Authors: Lin Li, Xiu-Li Yan, Hao-Yang Wang, Hang-Yu Zhou, Yu-Yan Li, Wenlong Ma, Jian Li, Rong-Rong Zhang, Lu Lv, Xing-Yao Huang, Hao Du, Tian-Shu Cao, Qing Ye, Hui Zhao, Yan Fu, Byung-Ho Kang, Qiang Ding, Aiping Wu, Yi-Jiao Huang, Cheng-Feng Qin

Journal: Cell

PubMed ID: 42476130

Doi: 10.1016/j.cell.2026.06.031

Products & Services: Gene Synthesis

Adhesion-derived condensates control component availability to regulate adhesion dynamics

Authors: Michal Dibus, Megan R Chastney, Giray Enkavi, Gautier Follain, Omkar Joshi, Ilpo Vattulainen, Johanna Ivaska

Journal: nature communications

PubMed ID: 42248878

Doi: 10.1038/s41467-026-74001-3

Products & Services: Gene Synthesis

Genome-Wide Identification, Characterization, and Functional Analysis of the GSK3/Shaggy-like Gene Family in Melon (Cucumis melo L.)

Authors: Peng Tian, Bing Li, Jingjing Zhang, Xiurui Gao, Wei Liu, Bowen Liu, Zhaowei Li, Jing Yang, Mengyuan Su, Jige Dang, Yanrong Wu

Journal: Horticulturae

Doi: 10.3390

Products & Services: Gene Synthesis