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Structural visualization of HECT-type E3 ligase Ufd4 accepting and transferring
Authors: Xiangwei Wu, Huasong Ai, Junxiong Mao, Hongyi Cai, Lu-Jun Liang, Zebin Tong, Zhiheng Deng, Qingyun Zheng, Lei Liu, Man Pan
Journal: nature COMMUNICATION
PubMed ID: 40341121
Doi: doi.org/10.1038/s41467-025-59569-6
Fe(III)−H2O2 as an Alternative Oxidant for Catalytic Sulfoxidation in Cytochrome P450 Enzymes: Combined Theoretical and Experimental Evidence
Authors: Musen Li, Langxing Liao, Zhihui Jiang, Zongyu Bao, Shengbiao Ji, Binju Wang
Journal: ACS Catalysis
Doi: doi.org/10.1021/acscatal.5c01673
Products & Services: Gene Synthesis   Codon Optimization   
An evolutionarily unique viral RdRP suggests a common dual-function feature of the priming element
Authors: Hengxia Jia, Shunli Liu, Guibo Rao, Qiaojie Liu, Jiqin Wu, Sheng Cao, Peng Gong
Journal: Sci Adv
PubMed ID: 40249801
Doi: 10.1126/sciadv.adv9640
Products & Services: Gene Synthesis   Custom Vector Construction   
Cryo-EM structures of the small-conductance Ca2+-activated KCa2.2 channel
Authors: Young-Woo Nam, Dohyun Im, Ana Santa Cruz Garcia, Marios L Tringides, Hai Minh Nguyen, Yan Liu, Razan Orfali, Alena Ramanishka, Grigore Pintilie, Chih-Chia Su, Meng Cui, Diomedes E Logothetis, Edward W Yu, Heike Wulff, K George Chandy, Miao Zhang
Journal: Nat Commun
PubMed ID: 40246884
Doi: /10.1038/s41467-025-59061-1
Products & Services: Gene Synthesis   
The structure and function of the ghrelin receptor coding for drug actions
Authors: Yuki Shiimura, Dohyun Im, Ryosuke Tany, Hidetsugu Asada, Ryoji Kise, Eon Kurumiya, Hideko Wakasugi-Masuho, Satoshi Yasuda, Kazuma Matsui, Jun-Ichi Kishikawa, Takayuki Kato, Takeshi Murata, Masayasu Kojima, So Iwata, Ikuo Masuho
Journal: Nat Struct Mol Biol
PubMed ID: 39833471
Doi: 39833471
Products & Services: Gene Synthesis   
Enhancing the Anticancer Activity of a Carcinoma-Directed Peptide–HLA-I Fusion Protein by Armoring with Mutein IFNα
Authors: Douwe Freerk Samplonius , Anne Paulien van Wijngaarden , Lisanne Koll , Xiurong Ke , Wijnand Helfrich
Journal: Int J Mol Sci
PubMed ID: 40243928
Doi: ijms26073178
Products & Services: Gene Synthesis   
SUMO4 promotes SUMO deconjugation required for DNA double-strand-break repair
Authors: Alexander J Garvin, Alexander J Lanz, George E Ronson, Matthew J W Mackintosh, Katarzyna Starowicz, Alexandra K Walker, Yara Aghabi, Hannah MacKay, Ruth M Densham, Jai S Bhachoo, Aneika C Leney, Joanna R Morris
Journal: Mol Cell
PubMed ID: 40054443
Doi: 10.1016/j.molcel.2025.02.004
ER nests are specialized ER subdomains in Arabidopsis where peroxisomes and lipid droplets form
Authors: Zachary J Wright , Nathan E Tharp , Bonnie Bartel
Journal: Developmental cell
Doi: 10.1016/j.devcel.2025.03.005
Structure-Guided Development of Chemically Tailored Peptide Binders of RNF43/ZNRF3 to Enable Versatile Design of Membrane Protein-Targeting PROTACs
Authors: Jibin Cui , Qingyun Zheng , Yicheng Weng , Xiaoguo Zhai , Zhen Su , Yunxiang Du , Xiaoxiong Wei , Yuanyuan Yu , Qian Qu , Man Pan
Journal: ANALYTICAL CHEMISTRY
PubMed ID: 40000409
Doi: doi.org/10.1002/anie.202501488
Products & Services: Codon Optimization   Gene Synthesis   
EXPERT expands prime editing efficiency and range of large fragment edits
Authors: Youcai Xiong , Yinyu Su , Ruigao He , Xiaosong Han , Sheng Li , Minghuan Liu , Xiaoning Xi , Zijia Liu , Heng Wang , Shengsong Xie , Xuewen Xu , Kui Li , Jifeng Zhang , Jie Xu , Xinyun Li , Shuhong Zhao , Jinxue Ruan
Journal: Nat Commun
PubMed ID: 39939583
Doi: 10.1038/s41467-025-56734-9
Products & Services: Gene Synthesis   

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