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Modulating ER-mitochondrial crosstalk to revitalize implant osseointegration in diabetes through an injectable hydrogel platform

Authors: Hao Wang, Ziqi Qin, Beilei Liu, Chen Li, Yifeng Ruan, Yifei Shen, Hao Li, Irene Shuping Zhao, Xueqi Gan

Journal: Chemical Engineering Journal

Doi: 10.1016/j.cej.2026.177208

Products & Services: Custom DNA/RNA Oligos

Beyond CAT, BSD, and URA: SUL, A novel selectable marker for Cyanidioschyzon merolae

Authors: Yissell Borges-Rodríguez, Martha R Stark, Elise Kerckhofs, Julie Mueller, Kyle J Lauersen, Daniel Schubert, Stephen D Rader

Journal: New biotechnology

PubMed ID: 41643937

Doi: 10.1016/j.nbt.2026.01.012

Products & Services: Gene Synthesis

Cholesterol analogs modulate lipid nanoparticle performance for mRNA delivery after lyophilization and enable ocular disease therapy

Authors: Ting Wang, Wanqi Li, Jianyang Chen, Sitian Cheng, Min Gao, Chengyu Jiang, Chengyu Jiang, Bingyi Hu, Tzu-Cheng Sung, Akon Higuchi

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.103044

Products & Services: Custom mRNA synthesis

Engineered haptoglobin β fusion protein targets myoglobin and ameliorates rhabdomyolysisassociated acute kidney injury

Authors: Ning Li, Yuru Wang, Lu Han, Ou Qiao, Xinyue Wang, Herui Hao, Xin Chen, Pengtao Wang, Sania Saeed, Jing Wang, Fengjiao Bao, Yingjie Hou, Li Zhang, Xiaohong Duan, Shuquan Rao, Yanhua Gong

Journal: EMBO Molecular Medicine

PubMed ID: 42185634

Doi: 10.1038/s44321-026-00454-0

Products & Services: Synthetic Guide RNA

Radiotherapy synergizes with an inducible AAVbased immunotherapy platform to program local and systemic antitumor immunity

Authors: Sonia Marco, Myriam Fernández, Beatriz Honorato, Nerea Juanarena, Cristina Sainz, Ainhoa Andueza, David J Gould, Seth Anderson, Carlos de Andrea, Paulo Pérez Domínguez, Paolo Wong, Carlos Vásquez, Irene Narinda, Carmen Unzu, Sergio Isola, Beatriz Tavira, Mikel Ariz, Gracián Camps, Miguel F Sanmamed, Julián Pardo, Sara Labiano, Marta M Alonso, Javier Marco-Sanz, Elizabeth Guruceaga, María Collantes, Jon Ander Simón, Iván Peñuelas, Joaquín Fernández-Irigoyen, Enrique Santamaría, Jesús Prieto, Juan Dubrot

Journal: Cancer Cell

PubMed ID: 41875889

Doi: doi.org/10.1016

Products & Services: Gene Synthesis

Structural basis for the subtype-selective activation of KCa3.1 channels

Authors: Alena Ramanishka, Joshua A. Nasburg, Yang Xu, Xinyi Ma, Reza Mehvar, Meng Cui, Young-Woo Nam, Heike Wulff, Miao Zhang

Journal: Structure

Doi: 10.1016/j.bpj.2025.11.2173

Products & Services: Gene Synthesis

A nanobody-based proteolysis-targeting chimera offers broad-spectrum protection against diverse influenza virus infections

Authors: Yichao Zhuang, Lei Chen, Chen Qin, Puze Chen, Lulu Feng, Weipeng Lin, Jiaqi Li, Yaping Zhang, Congcong Wang, Jianzhong Shi, Guohua Deng, Xianying Zeng, Pengfei Cui, Yanbing Li, Yongping Jiang, Hualan Chen, Huihui Kong

Journal: Signal transduction and targeted therapy

PubMed ID: 42140901

Doi: 10.1038/s41392-026-02666-9

Products & Services: Protein Electrophoresis and Western

NIR-II Biomimetic Nanoplatform Optogenetic CD274 Editing of HNSCC Immunogenicity for Enhanced Photoimmunotherapy

Authors: Yang Chen, Longcai Liu, Xiaojuan Hu, Yilin Huang, Shijie Yao, Lichen Ji, Hai Zou, Xiaozhou Mou, Yu Cai

Journal: Materials Today Bio

Doi: 10.1016/j.mtbio.2026.102803

Products & Services: Synthetic Guide RNA CRISPR Plasmids

Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis

Authors: Peng Qian, Yuxin Li, Yifeng Han, Chun Xu, Peng Zou, Fuming Yang, Xiaozhen Kang, Mengdi Wu, Jie Dong, Zhengyun Zou, Jiwu Wei

Journal: Immunity