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Augmenting macropinocytosis enhances the apoptotic body-mediated tumor deep penetration of nanomedicines

Authors: Bin Wan, Qiu Wang, Xiwei Jiang, Xianlu Zhang, Xiaoyuan Fan, Fengxiang Liu, Shipeng Ning, Meiling Zhang, Dongyan Liang, Lianwen Qi, Zhonggui He, Yinglei Zhai, Kaiyuan Wang, Jin Sun, Wei Tang

Journal: Chinese Chemical Letters

Doi: 10.1016/j.cclet.2025.112285

Products & Services: Peptide Synthesis

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol-Mediated Cellular Uptake for miRNA Nano-Drugs

Authors: Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan

Journal: Advanced science

PubMed ID: 42658549

Doi: 10.1002/advs.77389

Products & Services: Peptide Synthesis

Nociceptive sensory nerves induce an IL4Rαhi anti-inflammatory macrophage subset that protects against kidney ischemia-reperfusion injury

Authors: Shun Zhang, Xiuwu Pan, Hailong Liu, Kaikai Chen, Shenggen Yu, Yu Shen, Jing Li, Ding Xu, Wang Zhou, Haibo Shen, Ying Wang, Xingang Cui

Journal: Kidney International

PubMed ID: 42176775

Doi: 10.1016/j.kint.2026.04.022

Products & Services: Recombinant Proteins

Caveola and Its Resident Proteins, Caveolin-1 and -2, Play Critical Roles in the Pathogenesis of nAMD and PCV

Authors: Richard Ming Chuan Yu, Gokce Oguz, Nai Yang Fu, Waseem Ahamed Shihabuddeen, Christine Cheung, Xiaomeng Wang, Tien Yin Wong, Chui Ming Gemmy Cheung, Adaikalavan Ramasamy, Yasuo Yanagi

Journal: investigative ophthalmology & visual science

PubMed ID: 42549844

Doi: 10.1167/iovs.67.10.10

Products & Services: Catalog IVT RNA products

siRNA-mediated mismatch repair disruption synergizes with oxaliplatin to restore immune surveillance in microsatellite-stable colorectal cancer

Authors: Jing Ni, Guantao He, Hongwei Wang, Yao Qin, Jianping Guo, Yuhang Wang, Keqian Du, Di Zhang, Yanxin Luo, Jiang Xia, Yingjie Li, Lin-Ping Wu

Journal: Molecular cancer

Doi: doi.org/10.1186/s12943-026-02752-0

Products & Services: Custom mRNA synthesis

A non-classical biosynthetic route enables tocopherol synthesis in bacteria

Authors: Yang Zhang, Zhizhen Li, Lichuang Cao, Yan Wang, Junyi Wang, Haofeng Chen, Wenhao Li, Xinyu Gao, Qingchen Li, Zhengxin Chen, Kaixuan Xu, Xiangpeng Yang, Xiangrui Wu, Jintao Luo, Jianzhong Liu, Jifeng Yuan

Journal: nature metabolism

PubMed ID: 42509462

Doi: 10.1038/s42255-026-01576-y

Products & Services: Codon Optimization

RNA synthesis and substrate analog inhibition in the CCHFV polymerase

Authors: Hengxia Jia, Bo Tang, Shunli Liu, Xin Wen, Fan Wu, Xiao Hu, Hu Zhou, Tingting Chong, Lincan Lv, Qiaojie Liu, Guibo Rao, Mingyu Wei, Xuping Jing, Sheng Cao, Fei Deng, Zhihong Hu, Bo Shu, Rui Gong, Jiqin Wu, Manli Wang, Peng Gong

Journal: Nature

Doi: 10.1038/s41586-026-10913-w

Products & Services: PCR Cloning and Subcloning

Sub1 contributes to heart failure with preserved ejection fraction driven by aging in mice

Authors: Di Zhao, Ling Lin, Yufei Zhou, Jiaying Wu, Ran Xu, Linnan Li, Xiaoxue Zhang, Hong Lin, Jienan Wang, Kunming Dai, Zhiwen Ding, Pan Gao, Jian Wu, Yunzeng Zou

Journal: Nature Communications

PubMed ID: 42402618

Doi: 10.1038/s41467-026-75237-9

Products & Services: Peptide Synthesis

Activation-induced SLC7A1 expression enhances T cell sensitivity to cGAMP-mediated STING signaling

Authors: Valentino Sudaryo, Dayanne R Carvalho, Jacqueline A Carozza, Xujun Cao, Courtney Kernick, Anthony F Cordova, J Michelle Lee, Theodore L Roth, Lingyin Li

Journal: Cell reports

PubMed ID: 42329763

Doi: 10.1016/j.celrep.2026.117580

A flexible antimicrobial peptide achieves pathogen selectivity through lipid-dependent membrane engagement

Authors: Jia-Tao Guo, Tian-Zhu Sun, Yuan-He Wang, Jiang-Miao Hu

Journal: antimicrobials and resistance

Doi: 10.1038/s44259-026-00253-0

Products & Services: Peptide Synthesis