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Metabolic Hijacking by Engineered Probiotics Reprograms Tumor Metabolism and Immune Microenvironment for Self-Reinforcing Photodynamic Immunotherapy

Authors: Shurong Qin, Qi Wang, Zhuangwei Zhang, Junhui Gu, Guanzhong He, Fei Zeng, Ruiyue Chen, Bangshun He, Yuzhen Wang, Meng Wang, Yujun Song

Journal: Journal of the American Chemical Society

PubMed ID: 41059938

Doi: 10.1021/jacs.5c10242

Products & Services: Recombinant Proteins

ZBP1 pathway promotes tumor immunogenicity in thecombinationofanti-HER2therapyandepigenetic therapy

Authors: Qishan Wang, Zhihao Wu, Yuanqin Yang, Chao Yang, Haoran Deng, Xingyue Zhou, Shuting Xu, Lingling Wu, Xiaochuan Hong, Xueni Yu, Lu Lu, Liufu Deng

Journal: Cell Reports

Doi: 10.1016/j.celrep.2025.116314

Products & Services: Proteins, Expression, Isolation and Analysis

Integration of humanized ROBO1 CAR in PD-1 locus in natural killer cells delivers synergistic tumor-killing effect against nonsmall cell lung cancer

Authors: Jia-Hao Tao, Jun Zhang, Chun-Yan Tang, Jia-Xi Duan, Wen-Jing Zhong, Chen-Yu Zhang, Yu-Biao Liu, Jin Ling, Hua-Shun Li, Yong Zhou, Cha-Xiang Guan

Journal: Cancer gene therapy

PubMed ID: 40913086

Doi: 10.1038/s41417-025-00957-x

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance

Authors: Rujia Si, Yihan Zhang, Bowen Hu, Yuxin Du, Dan Zou, Shaodi Wen, Xiaoyue Du, Xin Chen, Chen Peng, Shulei Fu, Shiying Zhu, Fan Du, Xiaofeng Sha, Ning Ding, Cong Xu, Bo Shen

Journal: Anti-Cancer Agents in Medicinal Chemistry

Doi: 10.2174/0118715206430859250915050817

Products & Services: Proteins, Expression, Isolation and Analysis

SOX4 Regulates Thermogenesis in Brown Adipose Tissue via Independent Complexes with EBF2 and PPAR

Authors: Shuai Wang, Ting He, Tong Fu, Yu Zhu, Yixin Wei, Wenlong Xie, Huanming Shen, Ya Luo, Boan Li, Huiling Guo, Weihua Li

Journal: Advanced Biology

PubMed ID: 40977422

Doi: 10.1002/adbi.202500224

Products & Services: Catalog Antibody

Protein M fusion proteins and uses

Authors: Jay Dela Cruz , Moreno Valley , CA

Journal: U.S. Patent

Doi: US11401309B2

Products & Services: Gene Synthesis Plasmid DNA Preparation Catalog Antibody Codon Optimization

Multifunctional NAC transcription factor SlJA2L integrates the ethylene pathway to orchestrate thermotolerance and fruit ripening in tomato

Authors: Yunfei Liang, Fang Ma, Shudi Huang, Chao Ma, Hongyan Shi, Fanyi Meng, Yinglu Chen, Han Dong, Rugang Chen, Xiangqiang Zhan

Journal: New Phytologist

PubMed ID: 40963426

Doi: 10.1111/nph.70571

Products & Services: Catalog Antibody

Optimized in vivo base editing restores auditory function in a DFNA15 mouse model

Authors: Man Wang, Ziyu Zhang, Xiaohan Wang, Liyan Zhang, Xiangyan Chen, Nianci Li, Qiuhan Sun, Yicheng Lu, Zuhong He, Hongbo Yang, Fangzhi Tan, Jieyu Qi, Renjie Chai

Journal: Nature Communications

PubMed ID: 40968144

Doi: 10.1038/s41467-025-63613-w.

Products & Services: Proteins, Expression, Isolation and Analysis

OsEHD1 and OsEHD2, two EH domain proteins targeted by E3 ubiquitin ligase OsBBI1, negatively modulate rice immunity against blast and bacterial blight diseases

Authors: Yan Bi, Yuqing Yan, Hui Wang, Leeza Tariq, Jiamu Wang, Dayong Li, Yayun Yang, Fengming Song

Journal: Crop Journal

Doi: doi.org/10.1016/j.cj.2025.09.003

Products & Services: Catalog Antibody

Multilevel regulation of c-di-GMP biosynthesis by cAMPsignalingincreasesShigellasonneifitnessand pathogenicity in response to bile salts

Authors: Mingfang Wang, Jia Zeng, Binbin Cui, Guangliang Wu, Xiayu Chen, Yikai Fu, Bing Gu, Yinyue Deng

Journal: Cell Rep