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StrepCaptureXP Magnetic Beads

The Strep-tag® II (WSHPQFEK) and Twin-Strep-tag® (WSHPQFEKGGGSGGGSGGSAWSHPQFEK) are widely adopted affinity tags for the purification of recombinant proteins in basic research, diagnostics, and biomanufacturing.
¥3800 在线订购包邮(港澳台除外)
L01075-1

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Product Description GenScript’s StrepCaptureXP Magnetic Beads (Cat. No. L01075) are next-generation affinity magnetic particles engineered for the efficient and high-throughput purification of Strep-tag® II and Twin-Strep-tag® fusion proteins. Functionalized with an innovatively engineered StrepCaptureXP ligand—a genetically optimized streptavidin variant—this product enables high-affinity, high-specificity capture proteins from complex biological lysates, including those derived from mammalian, bacterial, and insect expression systems.
Key Features ● High specificity and low background binding
● Alkali-tolerance is 0.1 M NaOH to 0.5 M NaOH
● Efficient, high-throughput purification, compatible with automated workflows
● Mild, reversible elution (50 mM Biotin)
● Broad buffer compatibility
● Robust performance across various expression systems
● Simple, streamlined operation
Selection Guide
StrepCaptureXP Magnetic Beads (Cat. No.: L01075) StrepCaptureXP Resin FF (Cat. No.: L01091) StrepCaptureXP Resin Lite (Cat. No.: L01114)
Recommended Applications High-throughput screening & small-scale purification Scalable purification & process development Routine research purification & small-scale protein preparation
If You Need ✓ High-throughput screening
✓ Automated parallel purification
✓ AI-driven protein screening and parallel evaluation of multiple protein candidates
✓ Fast turnaround and high first-pass success rate
✓ Scale-up purification
✓ Compatible with ÄKTA™ systems
✓ High stability for repeated purification cycles
✓ Cost-effective for long-term manufacturing and process development
✓ Flexible for small-scale protein preparation
✓ Easy-to-use format for manual purification
✓ Lower entry cost for routine research applications
✓ Challenging proteins including membrane proteins
Recommended Workflow Automated magnetic purification platforms and parallel purification workflows ÄKTA™ chromatography systems and scalable purification processes Manual purification or small-scale chromatography workflows
Typical Scale Small volume purification
(Recommended: <1 mL beads equivalent)
Medium- to large-scale purification Small-scale laboratory purification
Automation Compatibility Compatible with automated magnetic purification platforms (e.g., AmMag™ Quatro 1300 ) Compatible with ÄKTA™ chromatography systems Compatible with commonly used chromatography systems, including ÄKTA™ systems under recommended operating conditions (refer to Product Manual)
Binding Capacity 20–40 mg/mL beads 10–30 mg/mL resin 8–15 mg/mL resin
Reusability ≥30 purification cycles ≥100 purification cycles ≥35 purification cycles
Purity of Eluted Protein ≥90% (SDS-PAGE) ≥90% (SDS-PAGE) ≥90% (SDS-PAGE)
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Ligand StrepCaptureXP
Binding Capacity 20-40 mg protein/mL settled beads. (Binding capacity depends on the target protein, the type and position of the tag, and the molecular size)
Matrix Magnetic agarose beads
Average Particle Size 10-37μm
Elution Method Competitive elution with 50 mM Biotin
Reagent Compatibility Compatible with commonly used lysis reagents.
Reuse Capability ≥30 purification cycles when regenerated and stored as recommended.
Formulation 50% settled beads suspended in PBS (pH 7.2) with 0.1% ProClin300
Application high-throughput, efficient and automated purification of Strep-tag® II and Twin-strep-tag® proteins
Storage Stored at 2-8°C. Do not store at 0°C or below 0°C to avoid freezing the beads.
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StrepCaptureXP Magnetic Beads

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StrepCaptureXP Magnetic Beads

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Terms of Use 1) Intellectual Property Rights
This product may be covered by patents filed by GenScript Corporation. Purchase grants a non-transferable right to use the product and its components for research purposes only. Any resale, transfer, or commercial use is prohibited without prior authorization. For commercial licensing, contact product@genscript.com.

2) Third-Party Trademark Acknowledgement
All product and company names mentioned in this manual are trademarks or registered trademarks of their respective owners, including but not limited to: Strep-tag® II and Twin-Strep-tag® (registered trademarks of IBA GmbH), Triton® X-100 (registered trademark of The Dow Chemical Company), Tween® 20 (registered trademark of Croda International Plc) , are the property of their respective owners and are used for identification purposes only. GenScript is not sponsored by, affiliated with, or endorsed by the owners of these trademarks.
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For research and manufacturing use. Direct human use, including taking orally and injection are forbidden.