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IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes

Authors: Lei Bao, Christian F Guerrero Juarez, Jing Li, Manuela Pigors, Shirin Emtenani, Yingzi Liu, Aadil Ahmed, N Ishii, T Hashimoto, Bethany E Perez White, Stefan Green, Kevin Kunstman, Nicole C Nowak, Connor Cole, Virgilia Macias, Maria Sverdlov, M Allen McAlexander, Christopher McCrae, Christopher D Nazaroff, Enno Schmidt, Kyle T Amber

Journal: Nature Communications

PubMed ID: 40769980

Doi: 10.1038/s41467-025-62495-2.

Products & Services: Antibody Modification and Purification Services

A glyoxal-specific aldehyde signaling axis in Pseudomonas aeruginosa that influences quorum sensing and infection

Authors: Christopher J Corcoran, Bonnie J Cuthbert, David G Glanville, Mailyn Terrado, Diana Valverde Mendez, Benjamin P Bratton, Daniel E Schemenauer, Valerie L Tokars, Thomas G Martin, Lawrence W Rasmussen, Matthew C Madison, Andrew F Maule, Joshua W Shaevitz, Boo Shan Tseng, Julian P Whitelegge, Catherine Putonti, Amit Gaggar, Jordan R Beach, Jonathan A Kirk, Alfonso Mondragón, Abby R Kroken, Jonathan P Allen, Celia W Goulding, Andrew T Ulijasz

Journal: Nature Communications

PubMed ID: 40681494

Doi: 10.1038/s41467-025-61469-8

Products & Services: Protein and Antibody Isolation

The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI

Authors: Benjamin Bourgeois, Emil Spreitzer, Daniel Platero-Rochart, Margret Paar, Qishun Zhou, Sinem Usluer, Peter L J de Keizer, Boudewijn M T Burgering, Pedro A Sánchez-Murcia, Tobias Madl

Journal: Nature Communications

PubMed ID: 40593617

Doi: 10.1038/s41467-025-60844-9

Products & Services: Bacterial Expression

Regulating the N-oxidation selectivity of P450BM3 monooxygenases for N-heterocycles through computer-assisted structure-guided design

Authors: Liu Yang, Zhongji Pu, Jianping Wu, Xiaofeng Liu, Zhe Wang, Haoran Yu, Liuwei Wang, Yan Meng, Gang Xu, Lirong Yang, Wenlong Zheng

Journal: Nature Communications

PubMed ID: 40659637

Doi: 10.1038/s41467-025-61773-3

Products & Services: Protein Electrophoresis and Western

API5 Phosphorylation Promotes Antiviral Immunity by Inhibiting Degradation of Cytosolic RNA Sensor RLRs

Authors: Tingjuan Deng, Jianan Xu, Linglong Qin, Xingbo Wang, Chenhe Lu, Yanming Huang, Da Liu, Yan Yan, Weiren Dong, Pinglong Xu, Jiyong Zhou

Journal: Advanced Science

PubMed ID: 40641422

Doi: 10.1002/advs.202505479

Products & Services: Protein and Antibody Isolation

Structures of the measles virus polymerase complex with non-nucleoside inhibitors and mechanism of inhibition

Authors: Yiru Wang, Lixia Zhao, Yi Zhang, Xiuxia Gao, Yannan Wang, Wenping Shi, Roger D Kornberg, Heqiao Zhang

Journal: Cell

PubMed ID: 40628260

Doi: 10.1016/j.cell.2025.06.017

Products & Services: Codon Optimization

Structural-functional characterization of the MIRO1-TRAK1 complex

Authors: Erika E Ravitch, Elana E Baltrusaitis, Tania A Perez, Kyle R Barrie, Adam R Fenton, Erika L F Holzbaur, Roberto Dominguez

Journal: Nature Communications

PubMed ID: 40615373

Doi: 10.1038/s41467-025-61174-6

Products & Services: Bacterial Expression

Lysosome-mediated aggregation of galactose-deficient IgA1 with transferrin receptor 1 links to IgA nephropathy

Authors: Meijun Si, Jingpeng Fu, Mengting Fang, Yunfei Lu, Junxuan Huang, Haojie Li, Peiyi Wang, Maofu Liao, Jian Zhu, Peiyao Li, Wenzhao Zhong, Zhifei Guo, Wei Yang, Zhiming Ye, Hongli Hu, Xueqing Yu

Journal: Nature Communications

PubMed ID: 40593574

Doi: 10.1038/s41467-025-60819-w

Products & Services: Protein and Antibody Isolation

Whole-genome identification, evolutionary decipherment, and expression profiling analyses of alcohol dehydrogenase family members in soybean (Glycine max (L.) Merr.)

Authors: Liang Wang, Jing Wang, Xianqin Wen, Wenhua Dongchen, Yumei Dong, Yuanyuan Li, Quan Liang, Yaqiong Zhang

Journal: Plant Stress

Doi: 10.1016/j.stress.2025.100975

Products & Services: Custom DNA/RNA Oligos

Modifying recombinant purple acid phosphatase using computational design

Authors: Aishwarya Venkatramani, Montader Ali, Olga Predeina, Jennifer C Molloy, Pietro Sormanni, Elizabeth A H Hall

Journal: European Biophysics Journal

PubMed ID: 40650743

Doi: 10.1007/s00249-025-01779-3

Products & Services: Protein and Antibody Isolation

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