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MechanismsofaureobasidinA inhibition and drug resistance in a fungal IPC synthase complex

Authors: Xinyue Wu , Xin Gong , Tian Xie

Journal: nature COMMUNICATION

PubMed ID: 40442105

Doi: doi.org/10.1038/s41467-025-60423-y

Products & Services: Protein and Antibody Isolation

Structural basis for hepatitis E virus neutralization by potent human antibodies

Authors: Luis M Molinos-Albert, Eduard Baquero, Cyril Planchais, Virginie Doceul, Hicham El Costa, Estelle Mottez, Vincent Mallet, Stanislas Pol, Matthew L Albert, Nicole Pavio, Cécile Alanio, Jordan D Dimitrov, Hugo Mouquet

Journal: SCIENCE ADVANCES

PubMed ID: 40333967

Doi: 10.1126/sciadv.adu8811

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Import mechanism of peroxisomal proteins with an N-terminal signal sequence

Authors: Michael L Skowyra , Tom A Rapoport

Journal: Nature Cell Biology

PubMed ID: 40346349

Doi: 10.1038/s41556-025-01662-5

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Expanding the σ54-dependent transcription process with orthogonal designs

Authors: Yiheng Liu, Shuyi Cai, Ziyi Zhang, Zhuoting Xie, Chenyue Guo, Yi-Ping Wang, Jianguo Yang

Journal: Nucleic Acids Research

PubMed ID: 40401558

Doi: 10.1093/nar/gkaf442

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Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis

Authors: Zhike Chen, Jian Yang, Qiang Zhang, Weibiao Zeng, Yi Liu, Wenxuan Hu, Linfu Chen, Jingjing Shen, Yu Miao, Zhisheng Xiao, Zhiqiang Wu, He Wang, Hui Shen, Cheng Ding, Qian Chen, Jun Zhao, Yang Yang

Journal: SCIENCE ADVANCES

PubMed ID: 40305619

Doi: 10.1126/sciadv.adv9571

Products & Services: Protein and Antibody Isolation

PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma

Authors: Jitong Zhou, Meng Gao, Shikun Zhang, Wing-Wa Guo, Wenzhi He, Minghe Zhang, Xi Chen, Cairang Dongzhi, Xiaomian Li, Yufeng Yuan, Weijie Ma

Journal: Advanced Science

PubMed ID: 40344394

Doi: 10.1002/advs.202501730

Products & Services: Protein Electrophoresis and Western

T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

Authors: Ji-Li Chen, Beibei Wang, Yongxu Lu, Elie Antoun, Olivia Bird, Philip G Drennan, Zixi Yin, Guihai Liu, Xuan Yao, Maya Pidoux, Adam Bates, Deshni Jayathilaka, Junyuan Wang, Brian Angus, Sally Beer, Alexis Espinosa, J Kenneth Baillie, Malcolm G Semple, ISARIC4C Investigators, Timothy Rostron, Craig Waugh, Paul Sopp, Julian C Knight, James N Fullerton, Mark Coles, Geoffrey L Smith, Alexander J Mentzer, Yanchun Peng, Tao Dong

Journal: Nature Communications

PubMed ID: 40348752

Doi: 10.1038/s41467-025-59370-5

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Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro

Authors: Haixia Su, Guofeng Chen, Hang Xie, Wanchen Li, Muya Xiong, Jian He, Hangchen Hu, Wenfeng Zhao, Qiang Shao, Minjun Li, Qiang Zhao, Yechun Xu

Journal: Nature Communications

PubMed ID: 40341069

Doi: 10.1038/s41467-025-59432-8

Products & Services: Protein Electrophoresis and Western

FcRn-silencing of IL-12Fc prevents toxicity of local IL-12 therapy and prolongs survival in experimental glioblastoma

Authors: Michal Beffinger, Linda Schellhammer, Betül Taskoparan, Sereina Deplazes, Ulisse Salazar, Nazanin Tatari, Frauke Seehusen, Leopold von Balthazar, Carl Philipp Zinner, Sabine Spath, Tala Shekarian, Marie-Françoise Ritz, Marta McDaid, Pascal Egloff, Iwan Zimmermann, Hideho Okada, E Sally Ward, Jack Rohrer, Markus A Seeger, Thorsten Buch, Gregor Hutter, Johannes Vom Berg

Journal: Nature Communications

PubMed ID: 40404625

Doi: 10.1038/s41467-025-59971-0

Products & Services: Protein Electrophoresis and Western

CRISPR-Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide-RNAs

Authors: Benjamín Durán-Vinet, Jo-Ann L. Stanton, Gert-Jan Jeunen, Ulla von Ammon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

Journal: Environmental DNA

Doi: doi.org/10.1002/edn3.70105

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