CD19 is a transmembrane glycoprotein primarily expressed on B lymphocytes. It plays two major roles in human B cells: acting as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and working within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways.
Scarless CD19 CAR circRNA (CVB3) encodes a CAR with no linker or junction sequences. Enables transient, non-integrating CAR expression for immune cell engineering with a clean, minimal RNA design.
CD19 CAR mRNA encodes a chimeric antigen receptor targeting B cells. Features Cap1, m1Ψ modification, and 100A tail for transient, non-integrating CAR expression. Ideal for generating CAR immune cells for B-cell malignancy research.
