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Localized expression pattern of miR-184 in Drosophila.

Mol Biol Rep.. 2011-01;  38(1):355-358
Li P, Peng J, Hu J, Xu Z, Xie W, Yuan L. Key Laboratory of Developmental Genes and Human Disease, Ministry of Education, Southeast University, Nanjing, 210009, People's Republic of China.
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摘要

MicroRNAs (miRNAs) are a kind of endogenous non-coding small RNAs whose specific functions in animals are generally important. Although functions of some miRNAs have been identified, the role of miR-184 remains unknown. Here, we determined the temporal and spatial expression pattern of miR-184 during the different development stages and tissues in Drosophila. Strikingly, miR-184 is expressed ubiquitously in Drosophila embryos, larvae and adults, its expression pattern shows a dynamic changes during the development of embryo, especially in the central nervous system. This expression profile suggests that miR-184 may act important function in Drosophila development.

关键词

miR-184; Expression pattern; Drosophila