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High-Mobility Group Box 1 From Hypoxic Trophoblasts Promotes Endothelial Microparticle Production and Thrombophilia in Preeclampsia.

Arterioscler. Thromb. Vasc. Biol.. 2018-06;

HuYae，YanRuhong，ZhangCe，ZhouZhichao，LiuMeng，WangCan，ZhangHong，DongLiang，ZhouTiantian，WuYi，DongNingzheng，WuQi

Products/Services Used	Details	Operation
Nucleic Acid Purification & Analysis	… added. After incubating for 30 minutes at room temperature in the dark, 500 μL of BB2× and hirudin (2 ATU/mL final concentration, GenScript, Piscataway, NJ, USA) were added for analysis. 2.5 Flow cytometric analysis. Labelled …	Get A Quote

摘要

Thrombophilia is a major complication in preeclampsia， a disease associated with placental hypoxia and trophoblast inflammation. Preeclampsia women are known to have increased circulating microparticles that are procoagulant， but the underlying mechanisms remain unclear. In this study， we sought to understand the mechanism connecting placental hypoxia， circulating microparticles， and thrombophilia.