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TWF2 Drives Tumor Progression and Sunitinib Resistance in Renal Cell Carcinoma through Hippo Signaling Suppression

Authors: Liangmin Fu, Wuyuan Liao, Youyan Tan, Hansen Lin, Kun Ye, Xinwei Zhou, Mingjie Lin, Kangbo Huang, Minyu Chen, Jietao Wei, Haoqian Feng, Yuhang Chen, Jinwei Chen, Bohong Guan, Shan Li, Zhengkun Zhang, Anze Yu, Zihao Feng, Lizhen Zhang, Guannan Shu, Jun Lu, Wei Chen, Yihui Pan, Jiefeng Yang, Junhang Luo, Li Luo

Journal: Advanced Science

PubMed ID: 40948085

Doi: 10.1002/advs.202506367

Products & Services: Peptide Services

Covariation MS uncovers a protein that controls cysteine catabolism

Authors: Haopeng Xiao, Martha Ordonez, Emma C. Fink, Taylor A. Covington, Hilina B. Woldemichael, Junyi Chen, Mika Sarkin Jain, Milan H. Rohatgi, Shelley M. Wei, Nils Burger, Muneeb A. Sharif, Julius Jan, Yaoyu Wang, Jonathan J. Petrocelli, Katherine Blackmore, Amanda L. Smythers, Bingsen Zhang, Matthew Gilbert, Hakyung Cheong, Sumeet A. Khetarpal, Arianne Smith, Dina Bogoslavski, Yu Lei, Laura Pontano Vaites, …Edward T. Chouchani

Journal: https://www.nature.com/ Nature

PubMed ID: 40963025

Doi: 10.1038/s41586-025-09535-5

UDP-glucose Activation of a G-protein/Sucrose Synthase 1 Signaling Supercomplex

Authors: Haiyan Jia, Fei Lou, Justin Watkins, Celio Cabral Oliveira, Christopher G. Tate and Alan M. Jones

Journal: biorxiv

Doi: doi.org/10.1101/2025.09.10.672744

Products & Services: Custom Vector Construction Catalog Peptides

AI-assisted design of ligands for lipocalin-2

Authors: Jacopo Sgrignani; Sara Buscarini; Patrizia Locatelli; Concetta Guerra; Alberto Furlan; Yingyi Chen; Giada Zoppi; Andrea Cavalli

Journal: Frontiers in Immunology

PubMed ID: 41019093

Doi: 10.3389/fimmu.2025.1631868

Browning white adipose tissue using adipose stromal cell-targeted resveratrol-loaded nanoparticles for combating obesity

Authors: Yujiao Zu; Ling Zhao; Lei Hao; Yehia Mechref; Masoud Zabet-Moghaddam; Peter A. Keyel; Mehrnaz Abbasi; Dayong Wu; John A. Dawson; Ruiwen Zhang; Shufang Nie; Naima Moustaid-Moussa; Mikhail G. Kolonin; Alexes C. Daquinag; Luis Brandi; Irfan Warraich; Susan K. San Francisco; Xiaocun Sun; Zhaoyang Fan; Shu Wang

Journal: Journal of controlled release : official journal of the Controlled Release Society

PubMed ID: 33766692

Doi: 10.1016/j.jconrel.2021.03.022

Products & Services: Peptide Synthesis

Structural insights into cationic amino acid transport and viral receptor engagement by CAT1

Authors: Lingyun Xia; Bingqian Lin; Rongfeng Zou; Yanyan Wu; Jiaying Xu; Yan Pan; Yuan Yuan; Shuo Li; Yang Yang; Xuemin Chen

Journal: Nature Communications

PubMed ID: 41408058

Doi: 10.1038/s41467-025-67704-6

Products & Services: Protein and Antibody Isolation

Structural insights into cationic amino acid transport and viral receptor engagement by CAT1

Authors: Lingyun Xia; Bingqian Lin; Rongfeng Zou; Yanyan Wu; Jiaying Xu; Yan Pan; Yuan Yuan; Shuo Li; Yang Yang; Xuemin Chen

Journal: Nature Communications

PubMed ID: 41408058

Doi: 10.1038/s41467-025-67704-6

Products & Services: Protein and Antibody Isolation

Functional characterisation of missense ceruloplasmin variants and real-world prevalence assessment of Aceruloplasminemia using population data

Authors: Nicole Ziliotto; Sara Lencioni; Martina Cirinciani; Alan Zanardi; Massimo Alessio; Giulia Sold ; Eleonora Da Pozzo; Rosanna Asselta; Andrea Caricasole

Journal: EBioMedicine

PubMed ID: 40043514

Doi: 10.1016/j.ebiom.2025.105625

Targeted Blockage of Pathological Extracellular Vesicles and Particles From Fibroblast-Like Synoviocytes for Osteoarthritis Relief: Proteomic Analysis and Cellular Effect

Authors: Bin Liu, Yansi Xian, Tao Shen, Yu Ben, Wenshu Wu, Yong Shi, Xueying An, Rui Peng, Wentian Gao, Wang Gong, Xiang Chen, Baosheng Guo, Qing Jiang

Journal: Journal of extracellular vesicles

PubMed ID: 40919882

Doi: 10.1002/jev2.70162

Products & Services: Protein and Antibody Isolation

Structure-based lead optimization of enterovirus D68 2A protease inhibitors

Authors: Bin Tan; Chang Liu; Kan Li; Prakash Jadhav; George Lambrinidis; Lan Zhu; Linda Olson; Haozhou Tan; Yu Wen; Antonios Kolocouris; Wei Liu; Jun Wang

Journal: Journal of Medicinal Chemistry

PubMed ID: 37857371

Doi: 10.1021/acs.jmedchem.3c00995