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A Scalable, Antibody-Free Lipid Nanoparticle Achieves Preferential mRNA Delivery to Human HSPCs In Vivo Without Conditioning

Authors: Eunyoung Kim, Ryan Zenhausern, Shivani Kapadia, Sylvanie Johnson, Skylar Cho, Joanne Choi, Kernyu Park, Edgard Diaz, Ananda R Podilapu, Ramachandran Kuppan, James E Dahlman, Hyejin Kim, Janghee Woo

Journal: Molecular Therapy

PubMed ID: 42920299

Doi: 10.1016/j.ymthe.2026.10.024

Products & Services: Custom mRNA synthesis

Machine learning–assisted directed evolution of plant Rubisco

Authors: Muhammad Fauzi, Takaaki Murakami, Ryota Usui, Ainur Botagarova, Daisuke Otani, Kentarou Sakaki, Shinsuke Tokumoto, Toshinori Imaizumi, Hisato Tatsuoka, Masahito Ogura, Jonathan Campbell, Nobuya Inagaki, Daisuke Yabe

Journal: Science advences

PubMed ID: 42842665

Doi: 10.1126/sciadv.aeh3246

Products & Services: Gene Synthesis

A neutralizing monoclonal antibody targeting species B adenoviruses largely mimics the DSG2 receptor engagement mechanism

Authors: Emilie Vassal-Stermann, Camille Berthollet, Wenli Zhang, Daphna Fenel, Anja Ehrhardt, André Lieber, Guy Schoehn, Grégory Effantin, Pascal Fender

Journal: Communications Biology

Doi: org/10.1038/s42003-026-11178-9

Carbonic anhydrase VIII regulates IP3R1-dependent Ca2+ signaling to coordinate insulin secretion and hepatic glucose production

Journal: Science advences

PubMed ID: 42853932

Doi: 10.1126/sciadv.aeh4948

An SAPK10-RISBZ1-ABT axis promotes endosperm-to-embryo ABA transport to enhance pre-harvest sprouting tolerance in rice

Authors: Guanghao Li, Yifeng Wang, Zhiyong Li, Babatunde Kazeem Bello, Delong Fan, Nan Lu, Yaqi Su, Xinyong Liu, Xixi Liu, Wanning Liu, Jia Li, Jiezheng Ying, Xiaohong Tong, Jie Huang, Yu Cheng, Yuxuan Hou, Guangheng Zhang, Yangjun Zhang, Kun Zhou, Xiaoshan Zeng, Jun Fang, Xianjun Song, Jian Zhang

Journal: Molecular Plant

PubMed ID: 42823798

Doi: 10.1016/j.molp.2026.09.017.

Products & Services: Monoclonal Antibody Services

MFN2-associated astrocyte dysfunction contributes to neuronal hyperexcitability and depressive-like behaviors

Authors: Feng-Xia Ma, Min Wang, Shuo-Yan Fang, Xiao-Xin Wang, Shen-Han Xu, Xin-Xin Zhao, Yu-Xiao Liu, Cong Wang, Chen Qiao, Qiu-Ling Wang, Lei Cao

Journal: Science advences

PubMed ID: 42886804

Doi: 10.1126/sciadv.aed8795

Products & Services: qPCR Oligos

Gliadin-specific CD4+ T cells exhibit functional diversity independent of TCR usage or epitope specificity

Authors: Claerwen M Jones, Jia Jia Lim, Stefan A Schattgen, Tiing Jen Loh, Hien Thy Dao, Mai T Tran, Angela Nguyen, Pirooz Zareie, Nathan J Felix, Paul G Thomas, Melinda Y Hardy, Jason A Tye-Din, Hugh H Reid, Jamie Rossjohn, Nicole L La Gruta

Journal: Science advences

PubMed ID: 42826196

Doi: 10.1126/sciadv.aei3175.

Products & Services: PCR Cloning and Subcloning

SMARCA5 facilitates cohesin localization at R-loops to prevent transcription-replication collisions

Authors: Boya Gao, Elizabeth M Irvin, Fengqi Zhang, Parminder Kaur, Ruoxi W Wang, Xiaofeng A Su, Zhubing Shi, Hong Wang, Li Lan

Journal: Cell death and differentiation

PubMed ID: 42946759

Doi: 10.1038/s41418-026-01888-2

Products & Services: PCR Cloning and Subcloning

Real-time single-molecule imaging in zebrafish embryos uncovers noncanonical translation

Authors: Maëlle Bellec, Jie Liang, Kenny Mattonet, Tatsuya Morisaki, Margaux Lay, Hans-Martin Maischein, Damien Avinens, Vincent Martinet, Delphine Muriaux, Timothy J Stasevich, Jérémy Dufourt, Didier Y R Stainier

Journal: Science advences

PubMed ID: 42842675

Doi: 10.1126/sciadv.aeb6883

Products & Services: Gene Synthesis

A bifunctional actuator to correct loss-of-function deficits in cardiac voltage-gated sodium channels

Authors: Lucile Fossier, Marc Yehya, Richard Z Zhuang, Sri Karthika Shanmugam, Ryan Mahling, Timothy Cho, Audrey Kochiss, Allen L Hsu, Sandra B Gabelli, Gordana Vunjak-Novakovic, Henry M Colecraft, Manu Ben-Johny

Journal: Science advences

PubMed ID: 42853924

Doi: 10.1126/sciadv.aeb2110

Products & Services: Catalog Antibodies