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Robust Antibody Levels in Both Diabetic and Non-Diabetic Individuals After BNT162b2 mRNA COVID-19 Vaccination

Authors: Hamad Ali, Abdulmohsen Alterki, Sardar Sindhu, Barrak Alahmad, Maha Hammad, Salman Al-Sabah, Mohammad Alghounaim, Mohammad H Jamal, Ali Aldei, Mohammad J Mairza, Maitham Husain, Sriraman Deverajan, Rasheed Ahmad, Preethi Cherian, Irina Alkhairi, Abdullah Alkandari, Jehad Abubaker, Mohamed Abu-Farha, Fahd Al-Mulla

Journal: Front Immunol

PubMed ID: 34899701

Doi: 10.3389/fimmu.2021.752233

Products & Services: Catalog Antibodies

Generation of a Novel High-Affinity Antibody Binding to PCSK9 Catalytic Domain with Slow Dissociation Rate by CDR-Grafting, Alanine Scanning and Saturated Site-Directed Mutagenesis for Favorably Treating Hypercholesterolemia

Authors: Zhengli Bai, Menglong Xu, Ying Mei, Tuo Hu, Panpan Zhang, Manman Chen, Wenxiu Lv, Chenchen Lu, Shuhua Tan

Journal: Biomedicines

PubMed ID: 34944600

Doi: 10.3390/biomedicines9121783

Products & Services: Mammalian Expression

Methodology to Quantify Collagen Subtypes and Crosslinks: Application in Minipig Cartilages

Authors: Benjamin J Bielajew, Jerry C Hu, Kyriacos A Athanasiou

Journal: Cartilage

PubMed ID: 34823380

Doi: 10.1177/19476035211060508

Products & Services: Catalog Peptides

Immuno-transcriptomic profiling of extracranial pediatric solid malignancies

Authors: Andrew S Brohl, Sivasish Sindiri, Jun S Wei, David Milewski, Hsien-Chao Chou, Young K Song, Xinyu Wen, Jeetendra Kumar, Hue V Reardon, Uma S Mudunuri, Jack R Collins, Sushma Nagaraj, Vineela Gangalapudi, Manoj Tyagi, Yuelin J Zhu, Katherine E Masih, Marielle E Yohe, Jack F Shern, Yue Qi, Udayan Guha, Daniel Catchpoole, Rimas J Orentas, Igor B Kuznetsov, Nicolas J Llosa, John A Ligon, Brian K Turpin, Daniel G Leino, Shintaro Iwata, Irene L Andrulis, Jay S Wunder, Silvia R C Toledo, Paul S Meltzer, Ching Lau, Beverly A Teicher, Heather Magnan, Marc Ladanyi, Javed Khan

Journal: Cell Rep

PubMed ID: 34818552

Doi: 10.1016/j.celrep.2021.110047

Products & Services: Codon Optimization

ACE Inhibitory Peptide from Skin Collagen Hydrolysate of as Potential for Protecting HUVECs Injury

Authors: Shuilin Cai, Nan Pan, Min Xu, Yongchang Su, Kun Qiao, Bei Chen, Bingde Zheng, Meitian Xiao, Zhiyu Liu

Journal: Mar Drugs

PubMed ID: 34940654

Doi: 10.3390/md19120655

Products & Services: Mammalian Expression

Kinetic proofreading of lipochitooligosaccharides determines signal activation of symbiotic plant receptors

Authors: Kira Gysel, Mette Laursen, Mikkel B Thygesen, Damiano Lironi, Zoltán Bozsóki, Christian T Hjuler, Nicolai N Maolanon, Jeryl Cheng, Peter K Bjørk, Maria Vinther, Lene H Madsen, Henriette Rübsam, Artur Muszyński, Arshia Ghodrati, Parastoo Azadi, John T Sullivan, Clive W Ronson, Knud J Jensen, Mickaël Blaise, Simona Radutoiu, Jens Stougaard, Kasper R Andersen

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34716271

Doi: 10.1073/pnas.2111031118

Products & Services: Insect Expression

A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants

Authors: Novalia Pishesha, Thibault J Harmand, Paul W Rothlauf, Patrique Praest, Ryan K Alexander, Renate van den Doel, Mariel J Liebeskind, Maria A Vakaki, Nicholas McCaul, Charlotte Wijne, Elisha Verhaar, William Pinney, Hailey Heston, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Ma Xenia G Ilagan, Robert Jan Lebbink, William J Buchser, Emmanuel J H J Wiertz, Sean P J Whelan, Hidde L Ploegh

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34654739

Doi: 10.1073/pnas.2116147118

Products & Services: Catalog Peptides cGMP Peptide Synthesis

First cases of SARS-CoV-2 infection in dogs and cats in Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Napawan Bunpapong, Supanat Boonyapisitsopa, Rachod Tantilertcharoen, Navapon Techakriengkrai, Sirilak Surachetpong, Ratanaporn Tangwangvivat, Kamol Suwannakarn, Alongkorn Amonsin

Journal: Transbound Emerg Dis

PubMed ID: 34739748

Doi: 10.1111/tbed.14383

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

Authors: Yaozong Chen, Lulu Sun, Irfan Ullah, Guillaume Beaudoin-Bussières, Sai Priya Anand, Andrew P Hederman, William D Tolbert, Rebekah Sherburn, Dung N Nguyen, Lorie Marchitto, Shilei Ding, Di Wu, Yuhong Luo, Suneetha Gottumukkala, Sean Moran, Priti Kumar, Grzegorz Piszczek, Walther Mothes, Margaret E Ackerman, Andrés Finzi, Pradeep D Uchil, Frank J Gonzalez, Marzena Pazgier

Journal: biorxiv

PubMed ID: 34845451

Doi: 10.1101/2021.11.24.469776

Products & Services: Endotoxin Detection & Removal System

AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway

Authors: Hoi Yin Mak, Qian Ouyang, Sergey Tumanov, Jiesi Xu, Ping Rong, Feitong Dong, Sin Man Lam, Xiaowei Wang, Ivan Lukmantara, Ximing Du, Mingming Gao, Andrew J Brown, Xin Gong, Guanghou Shui, Roland Stocker, Xun Huang, Shuai Chen, Hongyuan Yang

Journal: Nat Commun

PubMed ID: 34824276

Doi: 10.1038/s41467-021-27279-4

Products & Services: Protein and Antibody Isolation