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Bartonella type IV secretion effector BepC induces stress fiber formation through activation of GEF-H1

Authors: Chunyan Wang, Haoran Zhang, Jiaqi Fu, Meng Wang, Yuhao Cai, Tianyun Ding, Jiezhang Jiang, Jane E Koehler, Xiaoyun Liu, Congli Yuan

Journal: PLoS Pathog

PubMed ID: 33508039

Doi: 10.1371/journal.ppat.1009065

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SARS-CoV-2 entry into human airway organoids is serine protease-mediated and facilitated by the multibasic cleavage site

Authors: Anna Z Mykytyn, Tim I Breugem, Samra Riesebosch, Debby Schipper, Petra B van den Doel, Robbert J Rottier, Mart M Lamers, Bart L Haagmans

Journal: Elife

PubMed ID: 33393462

Doi: 10.7554/eLife.64508

Products & Services: Gene Synthesis

Chaperone-mediated autophagy sustains haematopoietic stem-cell function

Authors: Shuxian Dong, Qian Wang, Yun-Ruei Kao, Antonio Diaz, Inmaculada Tasset, Susmita Kaushik, Victor Thiruthuvanathan, Aliona Zintiridou, Edward Nieves, Monika Dzieciatkowska, Julie A Reisz, Evripidis Gavathiotis, Angelo D'Alessandro, Britta Will, Ana Maria Cuervo

Journal: Nature

PubMed ID: 33442062

Doi: 10.1038/s41586-020-03129-z

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An unprecedented insight into the catalytic mechanism of copper nitrite reductase from atomic-resolution and damage-free structures

Authors: Samuel L Rose, Svetlana V Antonyuk, Daisuke Sasaki, Keitaro Yamashita, Kunio Hirata, Go Ueno, Hideo Ago, Robert R Eady, Takehiko Tosha, Masaki Yamamoto, S Samar Hasnain

Journal: Sci Adv

PubMed ID: 33523860

Doi: 10.1126/sciadv.abd8523

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Norovirus-Specific CD8 T Cell Responses in Human Blood and Tissues

Authors: Ajinkya Pattekar, Lena S Mayer, Chi Wai Lau, Chengyang Liu, Olesya Palko, Meenakshi Bewtra, Hpap Consortium, Lisa C Lindesmith, Paul D Brewer-Jensen, Ralph S Baric, Michael R Betts, Ali Naji, E John Wherry, Vesselin T Tomov

Journal: Cell Mol Gastroenterol Hepatol

PubMed ID: 33444817

Doi: 10.1016/j.jcmgh.2020.12.012

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EXPRESSION OF E8^E2 IS REQUIRED FOR WART FORMATION BY MOUSE PAPILLOMAVIRUS 1 IN VIVO

Authors: Frank Stubenrauch, Elke Straub, Katrin Klein, Daniela Kramer, Thomas Iftner, Margaret Wong, Richard B S Roden

Journal: J Virol

PubMed ID: 33472931

Doi: 10.1128/JVI.01930-20

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Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF

Authors: Satoshi Yamanaka, Hidetaka Murai, Daisuke Saito, Gembu Abe, Etsuko Tokunaga, Takahiro Iwasaki, Hirotaka Takahashi, Hiroyuki Takeda, Takayuki Suzuki, Norio Shibata, Koji Tamura, Tatsuya Sawasaki

Journal: EMBO J

PubMed ID: 33470442

Doi: 10.15252/embj.2020105375

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CD4 Inhibits Helper T Cell Activation at Lower Affinity Threshold for Full-Length T Cell Receptors Than Single Chain Signaling Constructs

Authors: Deborah K Johnson, Wyatt Magoffin, Sheldon J Myers, Jordan G Finnell, John C Hancock, Taylor S Orton, Stephen P Persaud, Kenneth A Christensen, K Scott Weber

Journal: Front Immunol

PubMed ID: 33542711

Doi: 10.3389/fimmu.2020.561889

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A Whole-Cell Biosensor for Point-of-Care Detection of Waterborne Bacterial Pathogens

Authors: Ying Wu, Chien-Wei Wang, Dong Wang, Na Wei

Journal: ACS Synth Biol

PubMed ID: 33496568

Doi: 10.1021/acssynbio.0c00491

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The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks

Authors: Ann-Marie K Shorrocks, Samuel E Jones, Kaima Tsukada, Carl A Morrow, Zoulikha Belblidia, Johanna Shen, Iolanda Vendrell, Roman Fischer, Benedikt M Kessler, Andrew N Blackford

Journal: Nat Commun

PubMed ID: 33500419

Doi: 10.1038/s41467-020-20818-5

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