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Activation of the bacterial defenseassociated sirtuin system

Authors: Kaixiang Zhu, Kun Shang, Linyue Wang, Xia Yu, Lei Hua, Weihe Zhang, Bo Qin, Jia Wang, Xiaopan Gao, Hongtao Zhu, Sheng Cui

Journal: Communications Biology

PubMed ID: 39994439

Doi: doi.org/10.1038/s42003-025-07743-3

Products & Services: Gene Synthesis

Structures of HCoV-OC43 HR1 Domain in Complex with Cognate HR2 or Analogue EK1 Peptide

Authors: Xiuxiu He, Huanzhen Liu, Guang Yang, Lei Yan

Journal: Viruses-Basel

PubMed ID: 40143271

Doi: 10.3390/v17030343

Products & Services: Peptide Synthesis

Bioengineered protein nanocarrier facilitating siRNA escape from lysosomes for targeted RNAi therapy in glioblastoma

Authors: Yiliang Jin, Baoli Zhang, Jianru Li, Zhenxi Guo, Chen Zhang, Xuehui Chen, Long Ma, Zhuoran Wang, Haiyin Yang, Yong Li, Yuhua Weng, Yuanyu Huang, Xiyun Yan, Kelong Fan

Journal: SCIENCE ADVANCES

PubMed ID: 39970222

Doi: 10.1126/sciadv.adr9266

Products & Services: Gene Synthesis

Design of CoQ10 crops based on evolutionary history

Authors: Jing-Jing Xu, Yuan Lei, Xiao-Fan Zhang, Jian-Xu Li, Qiupeng Lin, Xiang-Dong Wu, Yu-Guo Jiang, Wenyi Zhang, Runtong Qian, Shu-Yi Xiong, Kuo Tan, Yu Jia, Qiang Zhou, Yan Jiang, Hang Fan, Yan-Bo Huang, Ling-Jian Wang, Ji-Yun Liu, Yu Kong, Qing Zhao, Lei Yang, Jinxing Liu, Yong-Hong Hu, Shuai Zhan, Caixia Gao, Xiao-Ya Chen

Journal: Cell

PubMed ID: 39952246

Doi: 10.1016/j.cell.2025.01.023

Products & Services: Custom Vector Construction

The TaCLE24b peptide signaling cascade modulates lateral root development and drought tolerance in wheat

Authors: Wen Yang, Man Feng, Kuohai Yu, Jie Cao, Guangxian Cui, Yumei Zhang, Huiru Peng, Yingyin Yao, Zhaorong Hu, Zhongfu Ni, Feng Qin, Fuminori Takahashi, Qixin Sun, Mingming Xin

Journal: Nature Communications

PubMed ID: 40000659

Doi: 10.1038/s41467-025-57291-x

Products & Services: Peptide Synthesis

RH3 enhances antiviral defense by facilitating small RNA loading into Argonaute 2 at endoplasmic reticulum–chloroplast membrane contact sites

Authors: Juan Huang, Juan Du, Yan Liu, Lu Lu, Yanzhuo Xu, Jianfei Shi, Qing Liu, Qi Li, Yang Liu, Yaqiu Chen, Meng Du, Yiming Zhao, Liangxiao Huo, Weiran Wang, Chenxi Ding, Liya Wei, Jianguo Wu, Yao-Wu Yuan, Jinfeng Chen, Ruixi Li, Feng Cui, Xiaoming Zhang

Journal: Nature Communications

PubMed ID: 40000658

Doi: 10.1038/s41467-025-57296-6

Products & Services: Codon Optimization

Activation of CAMK2 by pseudokinase PEAK1 represents a targetable pathway in triple negative breast cancer

Authors: Xue Yang, Xiuquan Ma, Tianyue Zhao, David R Croucher, Elizabeth V Nguyen, Kimberley C Clark, Changyuan Hu, Sharissa L Latham, Charles Bayly-Jones, Bao V Nguyen, Srikanth Budnar, Sung-Young Shin, Lan K Nguyen, Thomas R Cotton, Anderly C Chüeh, Terry C C Lim Kam Sian, Margaret M Stratton, Andrew M Ellisdon, Roger J Daly

Journal: Nature Communications

PubMed ID: 39984440

Doi: 10.1038/s41467-025-57046-8

Products & Services: Custom Vector Construction

CK2B Induces CD8+ T-Cell Exhaustion through HDAC8-Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti-PD-1 Therapy in Non-Small-Cell Lung Cancer

Authors: Shaochuan Liu, Shiya Ma, Gen Liu, Lingjie Hou, Yong Guan, Liang Liu, Yuan Meng, Wenwen Yu, Ting Liu, Li Zhou, Zhiyong Yuan, Shuju Pang, Siyuan Zhang, Junyi Li, Xiubao Ren, Qian Sun

Journal: Advanced Science

PubMed ID: 40013761

Doi: 10.1002/advs.202411053

Products & Services: Peptide Synthesis

Evaluation of Cas13d as a tool for genetic interaction mapping

Authors: Ghanem El Kassem, Jasmine Hillmer, Michael Boettcher

Journal: Nature Communications

PubMed ID: 39952934

Doi: 10.1038/s41467-025-56747-4

Products & Services: Gene Fragments

Double antibody sandwich ELISA based on rabbit monoclonal antibody targeting gD protein for the detection of bovine herpesvirus 1

Authors: Qiang Liu, Xiaoxia Niu, Lingling Jiang, Gang Zhang, Pu Wang, Sinong Zhang, Weifeng Gao, Huichen Guo, Yujiong Wang, Yong Li

Journal: Int J Biol Macromol

PubMed ID: 39929469

Doi: 10.1016/j.ijbiomac.2025.140671

Products & Services: Gene Synthesis