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Overlapping and separable activities of BRA-2 and HIM-17 promote occurrence and regulation of pairing and synapsis during Caenorhabditis elegans meiosis

Authors: Jitka Blazickova, Shalini Trivedi, Richard Bowman, Sowmya Sivakumar Geetha, Silma Subah, Michelle Scuzzarella, Alexander Chang, Uma R Chandran, Judith L Yanowitz, Sarit Smolikove, Verena Jantsch, Monique Zetka, Nicola Silva

Journal: Nature Communications

PubMed ID: 40082424

Doi: 10.1038/s41467-025-57862-y

Products & Services: Peptide Synthesis

Epstein-Barr virus infection promotes T cell dysregulation in a humanized mouse model of multiple sclerosis

Authors: Jessica R Allanach, Naomi M Fettig, Blair K Hardman, Ariel R Rosen, Vina Fan, Cynthia Chung, Erin J Goldberg, Zachary J Morse, Iryna Shanina, Galina Vorobeychik, Lisa C Osborne, Marc S Horwitz

Journal: SCIENCE ADVANCES

PubMed ID: 40043135

Doi: 10.1126/sciadv.adu5110

Products & Services: Peptide Synthesis

Elevated NAD+ drives Sir2A-mediated GCβ deacetylation and OES localization for Plasmodium ookinete gliding and mosquito infection

Authors: Yang Shi, Lin Wan, Mengmeng Jiao, Chuan-Qi Zhong, Huiting Cui, Jing Yuan

Journal: Nature Communications

PubMed ID: 40050296

Doi: 10.1038/s41467-025-57517-y

Products & Services: Catalog Antibodies

A globular protein exhibits rare phase behavior and forms chemically regulated orthogonal condensates in cells

Authors: Jinglei Nie, Xinyi Zhang, Zhijuan Hu, Wei Wang, Martin A Schroer, Jie Ren, Dmitri Svergun, Anyang Chen, Peiguo Yang, An-Ping Zeng

Journal: Nature Communications

PubMed ID: 40069234

Doi: 10.1038/s41467-025-57886-4

Products & Services: Gene Synthesis

Soft-matter-induced orderings in a solid-state van der Waals heterostructure

Authors: Kai Zhao, Baojuan Dong, Yuang Wang, Xiaoxue Fan, Qi Wang, Zhiren Xiong, Jing Zhang, Jinkun He, Kaining Yang, Minru Qi, Chengbing Qin, Tongyao Zhang, Maolin Chen, Hanwen Wang, Jianqi Huang, Kai Liu, Hanwei Huang, Kenji Watanabe, Takashi Taniguchi, Yaning Wang, Xixiang Zhang, Juehan Yang, Zhenwen Huang, Yongjun Li, Zhongming Wei, Jing Zhang, Shuoxing Jiang, Zheng Vitto Han, Funan Liu

Journal: Nature Communications

PubMed ID: 40064923

Doi: 10.1038/s41467-025-57690-0

Oral delivery of therapeutic proteins by engineered bacterial type zero secretion system

Authors: Xu Gong , Shan Liu , Bozhang Xia , Yichen Wan , Shuyi Zhang , Baoyan Zhang , Zehao Wang , Junge Chen , Fei Xiao , Xing-Jie Liang , Yun Yang

Journal: Nat Commun

PubMed ID: 39984501

Doi: 10.1038/s41467-025-57153-6

Products & Services: Gene Synthesis

EXPERT expands prime editing efficiency and range of large fragment edits

Authors: Youcai Xiong , Yinyu Su , Ruigao He , Xiaosong Han , Sheng Li , Minghuan Liu , Xiaoning Xi , Zijia Liu , Heng Wang , Shengsong Xie , Xuewen Xu , Kui Li , Jifeng Zhang , Jie Xu , Xinyun Li , Shuhong Zhao , Jinxue Ruan

Journal: Nat Commun

PubMed ID: 39939583

Doi: 10.1038/s41467-025-56734-9

Products & Services: Gene Synthesis

Self-assembly GSH response based Buforin IIb-Olaparib nanocombination synergistically promotes DNA damage for prostate cancer immunotherapy

Authors: Maosong Hu , Yuyu Zhu , Xinyi Tang , Jing Xu , Hanbin Ma , Zhihan Chen , Duo Chen , Wenyuan Wu , Xialin Chen , Rongrong He , Jing Zhou , Jinao Duan , Weiguo Chen , Hongyue Ma

Journal: Chemical Engineering Journal

Doi: 10.1016/j.cej.2025.160862

Products & Services: Peptide Synthesis

Deciphering molecular specificity in MCL-1/BAK interaction and its implications for designing potent MCL-1 inhibitors

Authors: Hudie Wei, Haolan Wang, Shuang Xiang, Jiaqi Wang, Lingzhi Qu, Xiaojuan Chen, Ming Guo, Xiaoyun Lu, Yongheng Chen

Journal: Cell Death Differ

PubMed ID: 39901037

Doi: 10.1038/s41418-025-01454-2

Products & Services: Peptide Synthesis

Expanding Cas12a Activity Control with an RNA G-Quadruplex at the 5′ end of CRISPR RNA

Authors: Wenjuan Huang, Jiaqi Wang, Cheng Wang, Yuanfang Liu, Wentao Li, Qiaozhen Chen, Junqiu Zhai, Zhenyang Xiang, Chaoxing Liu

Journal: Advanced Science

PubMed ID: 39721016

Doi: 10.1002/advs.202411305

Products & Services: Catalog Gene Editing