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Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy

Authors: Jiexin Li, Ruiqi Yang, Chen Zhang, Jonathan F Lovell, Yumiao Zhang

Journal: J Am Chem Soc

PubMed ID: 40065259

Doi: 10.1021/jacs.4c18511

Products & Services: Recombinant Proteins

Meiotic crossovers revealed by differential visualization of homologous chromosomes using enhanced haplotype oligo-painting in cucumber

Authors: Yafeng Wu，Zixuan Chen，Fengxiang Chen，Juan Su，Jianyu Han，Songqin Liu

Journal: Plant Biotechnol J

PubMed ID: 39661709

Doi: 10.1111/pbi.14546

Products & Services: Oligo pool

Examining the Role of Threonine Phosphorylation in Ubiquitin’s Function Using Chemical Protein Synthesis

Authors: Bingji Wang, Chuntong Li, Fangyu Zhao, Luyu Shi, Xu Li, Yijie Liu, Shuzhe Sun, Ligong Yuan, Maoshen Sun, Yingyue Zhang, Jing Shi, Lu-Jun Liang

Journal: JACS Au

Doi: doi/10.1021/jacsau.5c00067

Products & Services: Protein Electrophoresis and Western

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants

Authors: Shouya Feng, Matthew C Wierzbowski, Katja Hrovat-Schaale, Andreas Dumortier, Yaoyuan Zhang, Maria Zyulina, Paul J Baker, Thomas Reygaerts, Annemarie Steiner, Dominic De Nardo, Dhanya Lakshmi Narayanan, Florian Milhavet, Alberto Pinzon-Charry, Juan Ignacio Arostegui, Raju P Khubchandani, Matthias Geyer, Guilaine Boursier, Seth L Masters

Journal: nature immunology

PubMed ID: 39930093

Doi: 10.1038/s41590-025-02088-9

Products & Services: Mutagenesis Services

FLT1 and other candidate fetal haemoglobin modifying loci in sickle cell disease in African ancestries

Authors: Ambroise Wonkam, Kevin Esoh, Rachel M Levine, Valentina Josiane Ngo Bitoungui, Khuthala Mnika, Nikitha Nimmagadda, Erin A D Dempsey, Siana Nkya, Raphael Z Sangeda, Victoria Nembaware, Jack Morrice, Fujr Osman, Michael A Beer, Julie Makani, Nicola Mulder, Guillaume Lettre, Martin H Steinberg, Rachel Latanich, James F Casella, Daiana Drehmer, Dan E Arking, Emile R Chimusa, Jonathan S Yen, Gregory A Newby, Stylianos E Antonarakis

Journal: Nature Communications

PubMed ID: 40025045

Doi: 10.1038/s41467-025-57413-5

Products & Services: Endotoxin Detection & Removal System

Molecular glues of the regulatory ChREBP/14-3-3 complex protect beta cells from glucolipotoxicity

Authors: Liora S Katz, Emira J Visser, Kathrin F Plitzko, Marloes A M Pennings, Peter J Cossar, Isabelle L Tse, Markus Kaiser, Luc Brunsveld, Christian Ottmann, Donald K Scott

Journal: Nature Communications

PubMed ID: 40025013

Doi: 10.1038/s41467-025-57241-7

Products & Services: Peptide Services

Blockade of ZMIZ1-GATA4 Axis Regulation Restores Youthfulness to Aged Cartilage

Authors: Jiho Nam, Hyunmin Woo, Jihye Yang, Seok Jung Kim, Kwang Pyo Lee, Ji Hoon Yu, Tae Joo Park, Seong-Il Eyun, Siyoung Yang

Journal: Advanced Science

PubMed ID: 40040621

Doi: 10.1002/advs.202404311

Products & Services: Chemicals

Structures of complete HIV-1 TAR RNA portray a dynamic platform poised for protein binding and structural remodeling

Authors: Charles Bou-Nader, Katie A Link, Krishna C Suddala, Jay R Knutson, Jinwei Zhang

Journal: Nature Communications

PubMed ID: 40050622

Doi: 10.1038/s41467-025-57519-w

Products & Services: Peptide Synthesis

Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits

Authors: Loϊc Binan, Aiping Jiang, Serwah A Danquah, Vera Valakh, Brooke Simonton, Jon Bezney, Robert T Manguso, Kathleen B Yates, Ralda Nehme, Brian Cleary, Samouil L Farhi

Journal: Cell

PubMed ID: 40081369

Doi: 10.1016/j.cell.2025.02.012

Products & Services: Custom Vector Construction

Bacterial Hachiman complex executes DNA cleavage for antiphage defense

Authors: Yongqing Cui, Zhikang Dai, Yufei Ouyang, Chunyang Fu, Yanjing Wang, Xueting Chen, Kaiyue Yang, Shuyue Zheng, Wenwen Wang, Pan Tao, Zeyuan Guan, Tingting Zou

Journal: Nature Communications

PubMed ID: 40097437

Doi: 10.1038/s41467-025-57851-1