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New lessons on TDP-43 from old N furzeri killifish

Authors: Alexandra Louka, Sara Bagnoli, Jakob Rupert, Benjamin Esapa, Gian Gaetano Tartaglia, Alessandro Cellerino, Annalisa Pastore, Eva Terzibasi Tozzini

Journal: Aging Cell

PubMed ID: 34939315

Doi: 10.1111/acel.13517

Products & Services: Codon Optimization

Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1

Authors: Kyung-Mi Choi, Jung Hak Kim, Xiangmudong Kong, Meltem Isik, Jin Zhang, Hee-Woong Lim, John C Yoon

Journal: Cell Rep

PubMed ID: 34910916

Doi: 10.1016/j.celrep.2021.110104

Products & Services: Catalog Antibodies

Preclinical evaluation of a synthetic peptide vaccine against SARS-CoV-2 inducing multiepitopic and cross-reactive humoral neutralizing and cellular CD4 and CD8 responses

Authors: Belén Aparicio, Noelia Casares, Josune Egea, Marta Ruiz, Diana Llopiz, Sheila Maestro, Cristina Olagüe, Gloria González-Aseguinolaza, Cristian Smerdou, Ascensión López-Díaz de Cerio, Susana Inogés, Felipe Prósper, José R Yuste, Francisco Carmona-Torre, Gabriel Reina, Juan J Lasarte, Pablo Sarobe

Journal: Emerg Microbes Infect

PubMed ID: 34538222

Doi: 10.1080/22221751.2021.1978823

Products & Services: Mammalian Expression

Icariin inhibits the expression of IL-1β, IL-6 and TNF-α induced by OGD/R through the IRE1/XBP1s pathway in microglia

Authors: Zhen-Tao Mo, Jie Zheng, Yu-Ling Liao

Journal: Pharm Biol

PubMed ID: 34711127

Doi: 10.1080/13880209.2021.1991959

Products & Services: Plasmid DNA Preparation

VLDLR and ApoER2 are receptors for multiple alphaviruses

Authors: Lars E Clark, Sarah A Clark, ChieYu Lin, Jianying Liu, Adrian Coscia, Katherine G Nabel, Pan Yang, Dylan V Neel, Hyo Lee, Vesna Brusic, Iryna Stryapunina, Kenneth S Plante, Asim A Ahmed, Flaminia Catteruccia, Tracy L Young-Pearse, Isaac M Chiu, Paula Montero Llopis, Scott C Weaver, Jonathan Abraham

Journal: Nature

PubMed ID: 34929721

Doi: 10.1038/s41586-021-04326-0

Products & Services: Mammalian Expression

Bombyx mori Nucleopolyhedrovirus (BmNPV) Induces G2/M Arrest to Promote Viral Multiplication by Depleting

Authors: Qin Xiao, Zhan-Qi Dong, Yan Zhu, Qian Zhang, Xiu Yang, Miao Xiao, Peng Chen, Cheng Lu, Min-Hui Pan

Journal: Insects

PubMed ID: 34940186

Doi: 10.3390/insects12121098

Products & Services: Custom Vector Construction

Identification and Characterization Analysis of Transient Receptor Potential Mucolipin Protein of Fallén

Authors: Haitao Wang, Yan Dong, Baijie Wan, Yinghua Ji, Qiufang Xu

Journal: Insects

PubMed ID: 34940195

Doi: 10.3390/insects12121107

Products & Services: Catalog Peptides

Metabolic drug survey highlights cancer cell dependencies and vulnerabilities

Authors: Tea Pemovska, Johannes W Bigenzahn, Ismet Srndic, Alexander Lercher, Andreas Bergthaler, Adrián César-Razquin, Felix Kartnig, Christoph Kornauth, Peter Valent, Philipp B Staber, Giulio Superti-Furga

Journal: Nat Commun

PubMed ID: 34907165

Doi: 10.1038/s41467-021-27329-x

Products & Services: Custom Vector Construction

Calibration of two validated SARS-CoV-2 pseudovirus neutralization assays for COVID-19 vaccine evaluation

Authors: Yunda Huang, Oleg Borisov, Jia Jin Kee, Lindsay N Carpp, Terri Wrin, Suqin Cai, Marcella Sarzotti-Kelsoe, Charlene McDanal, Amanda Eaton, Rolando Pajon, John Hural, Christine M Posavad, Katherine Gill, Shelly Karuna, Lawrence Corey, M Juliana McElrath, Peter B Gilbert, Christos J Petropoulos, David C Montefiori

Journal: Sci Rep

PubMed ID: 34907214

Doi: 10.1038/s41598-021-03154-6

Products & Services: Custom Vector Construction

Protective effects of combining monoclonal antibodies and vaccines against the Plasmodium falciparum circumsporozoite protein

Authors: Lawrence T Wang, Lais S Pereira, Patience K Kiyuka, Arne Schön, Neville K Kisalu, Rachel Vistein, Marlon Dillon, Brian G Bonilla, Alvaro Molina-Cruz, Carolina Barillas-Mury, Joshua Tan, Azza H Idris, Joseph R Francica, Robert A Seder

Journal: PLoS Pathog

PubMed ID: 34871332

Doi: 10.1371/journal.ppat.1010133

Products & Services: Peptide Synthesis