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WIN site inhibition disrupts a subset of WDR5 function
Authors: Andrew J Siladi, Jing Wang, Andrea C Florian, Lance R Thomas, Joy H Creighton, Brittany K Matlock, David K Flaherty, Shelly L Lorey, Gregory C Howard, Stephen W Fesik, April M Weissmiller, Qi Liu, William P Tansey
Journal: Sci Rep
PubMed ID: 35115608
Doi: 10.1038/s41598-022-05947-9
Products & Services: Gene Synthesis   
TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A
Authors: X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama, H Broder Schmidt, Beryl B Cummings, David W Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D Rubien, Karen Jansen-West, Casey N Cook, Sarah Pickles, Björn Oskarsson, Neill R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Dennis W Dickson, James Shorter, Sua Myong, Eric M Green, William W Seeley, Leonard Petrucelli, Aaron D Gitler
Journal: Nature
PubMed ID: 35197626
Doi: 10.1038/s41586-022-04424-7
Products & Services: Custom Vector Construction   
TAMpepK Suppresses Metastasis through the Elimination of M2-Like Tumor-Associated Macrophages in Triple-Negative Breast Cancer
Authors: Chanju Lee, Soyoung Kim, Chanmi Jeong, Inhee Cho, Juyeon Jo, Ik-Hwan Han, Hyunsu Bae
Journal: Int J Mol Sci
PubMed ID: 35216272
Doi: 10.3390/ijms23042157
Products & Services: Peptide Synthesis   
From In Vitro Data to In Vivo Interspecies Danger Communication: A Study of Chemosensing via the Mouse Grueneberg Ganglion
Authors: Ana Catarina Lopes, Julien Brechbühl, Flavio Ferreira, Marjorie Amez-Droz, Marie-Christine Broillet
Journal: Animals (Basel)
PubMed ID: 35158677
Doi: 10.3390/ani12030356
Products & Services: Mammalian Expression   
Far-Red Light Triggered Production of Bispecific T Cell Engagers (BiTEs) from Engineered Cells for Antitumor Application
Authors: Cuilin Zhang, Yingjun Shi, Lingjie Wu, Chenyi Wang, Naishun Liao, Fei Wang, Bixing Zhao, Yingchao Wang, Xiaolong Liu
Journal: ACS Synth Biol
PubMed ID: 35113526
Doi: 10.1021/acssynbio.1c00523
Products & Services: ELISA Kits   
The small heat shock protein HSPB5 attenuates the severity of lupus nephritis in lupus-prone mice
Authors: Spencer Iner Thomas Berg, Justin Knapp, Marsela Braunstein, Cody Shirriff
Journal: Autoimmunity
PubMed ID: 35137667
Doi: 10.1080/08916934.2022.2027921
Products & Services: Endotoxin Detection & Removal System   
SARS-CoV2 variant-specific replicating RNA vaccines protect from disease and pathology and reduce viral shedding following challenge with heterologous SARS-CoV2 variants of concern
Authors: David W Hawman, Kimberly Meade-White, Jacob Archer, Shanna S Leventhal, Drew Wilson, Carl Shaia, Samantha Randall, Amit P Khandhar, Kyle Krieger, Tien-Ying Hsiang, Michael Gale, Peter Berglund, Deborah Heydenburg Fuller, Heinz Feldmann, Jesse Erasmus
Journal: Elife
PubMed ID: 35191378
Doi: 10.7554/eLife.75537
Products & Services: Protein and Antibody Isolation   
Deleterious variants in CRLS1 lead to cardiolipin deficiency and cause an autosomal recessive multi-system mitochondrial disease
Authors: Richard G Lee, Shanti Balasubramaniam, Maike Stentenbach, Tom Kralj, Timothy McCubbin, Benjamin Padman, Janine Smith, Lisa G Riley, Archana Priyadarshi, Liuyu Peng, Madison R Nuske, Richard Webster, Ken Peacock, Philip Roberts, Zornitza Stark, Gabrielle Lemire, Yoko A Ito, Kym M Boycott, Michael T Geraghty, Jan Bert Klinken, Sacha Ferdinandusse, Ying Zhou, Rebecca Walsh, Esteban Marcellin, David R Thorburn, Tony Rosciolli, Janice Fletcher, Oliver Rackham, Frédéric M Vaz, Gavin E Reid, Aleksandra Filipovska
Journal: Hum Mol Genet
PubMed ID: 35147173
Doi: 10.1093/hmg/ddac040
Products & Services: Protein Tools   
Functional characterization of tyrosine decarboxylase genes that contribute to acteoside biosynthesis in Rehmannia glutinosa
Authors: Yan Hui Yang, Mu Rong Yang, Jian Yu Zhu, Ke Wei Dong, Yan Jie Yi, Rui Fang Li, Lei Zeng, Chang Fu Zhang
Journal: Planta
PubMed ID: 35147783
Doi: 10.1007/s00425-022-03849-8
Products & Services: Protein Tools   
Non-clinical immunogenicity, biodistribution and toxicology evaluation of a chimpanzee adenovirus-based COVID-19 vaccine in rat and rhesus macaque
Authors: Xuedong Dai, Weijun Zhao, Xin Tong, Wei Liu, Xianhuan Zeng, Xiaohui Duan, Hua Wu, Lili Wang, Zhen Huang, Xinying Tang, Yong Yang
Journal: Arch Toxicol
PubMed ID: 35226134
Doi: 10.1007/s00204-021-03221-x
Products & Services: Catalog Antibodies   
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