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Discovery, Herbicidal Activity and Biosynthesis of a Novel Natural Tetramic Acid from Alternaria Species

Authors: He Wang, Yanjing Guo, Qing Liu, Jing Zhang, Qianlong Zhang, Mingying Yang, Qizhen Chen, Sheng Qiang, Bernal E Valverde, Shiguo Chen

Journal: Advanced Science

PubMed ID: 40278415

Doi: 10.1002/advs.202416188

Products & Services: Gene Synthesis

Novel Bivalent mRNA-LNP Vaccine for Highly Effective Protection against Pneumonic Plague

Authors: Uri Elia, Yinon Levy, Hila Cohen, Ayelet Zauberman, David Gur, Inbal Hazan-Halevy, Moshe Aftalion, Shani Benarroch, Erez Bar-Haim, Orit Redy-Keisar, Ofer Cohen, Dan Peer, Emanuelle Mamroud

Journal: Advanced Science

PubMed ID: 40279638

Doi: 10.1002/advs.202501286

Products & Services: Peptide Synthesis

BMAL1–HIF2A heterodimer modulates circadian variations of myocardial injury

Authors: Wei Ruan, Tao Li, In Hyuk Bang, Jaewoong Lee, Wankun Deng, Xinxin Ma, Cong Luo, Fang Du, Seung-Hee Yoo, Boyun Kim, Jiwen Li, Xiaoyi Yuan, Katherine Figarella, Yu A. An, Yin-Ying Wang, Yafen Liang, Matthew DeBerge, Dongze Zhang, Zhen Zhou, Yanyu Wang, Joshua M. Gorham, Jonathan G. Seidman, Christine E. Seidman, Sary F. Aranki, …Holger K. Eltzschig

Journal: Nature

PubMed ID: 40269168

Doi: 10.1038/s41586-025-08898-z

Products & Services: Catalog Antibodies

Josephin Domain Containing 2 (JOSD2) inhibition as Pan-KRAS-mutation-targeting strategy for colorectal cancer

Authors: Tao Yuan, Yue Liu, Ruilin Wu, Meijia Qian, Weihua Wang, Yonghao Li, Hongdao Zhu, Jia’er Wang, Fujing Ge, Chenming Zeng, Xiaoyang Dai, Ronggui Hu, Tianhua Zhou, Qiaojun He, Hong Zhu & Bo Yang

Journal: Nature Communications

PubMed ID: 40240366

Doi: 10.1038/s41467-025-58923-y

Products & Services: Catalog Antibodies

A non-tethering role for the Drosophila Pol θ linker domain in promoting damage resolution

Authors: Justin R Blanch, Nicholas Woodward, Manan Krishnamurthy, Mitch McVey

Journal: Nucleic Acids Research

PubMed ID: 40275613

Doi: 10.1093/nar/gkaf304

Products & Services: Protein Electrophoresis and Western

Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance

Authors: Amanda L. Waterbury, Jonatan Caroli, Olivia Zhang, Paloma R. Tuttle, Chao Liu, Jiaming Li, Ji Sung Park, Samuel M. Hoenig, Marco Barone, Airi Furui, Andrea Mattevi & Brian B. Liau

Journal: Nature Communications

PubMed ID: 40175327

Doi: 10.1038/s41467-025-57477-3

Products & Services: Peptide Synthesis

Mechanistic insights into the structure-based design of a CspZ-targeting Lyme disease vaccine

Authors: Kalvis Brangulis, Jill Malfetano, Ashley L. Marcinkiewicz, Alan Wang, Yi-Lin Chen, Jungsoon Lee, Zhuyun Liu, Xiuli Yang, Ulrich Strych, Dagnija Tupina, Inara Akopjana, Maria-Elena Bottazzi, Utpal Pal, Ching-Lin Hsieh, Wen-Hsiang Chen & Yi-Pin Lin

Journal: Nature Communications

PubMed ID: 40189575

Doi: 10.1038/s41467-025-58182-x

Products & Services: Gene Synthesis

Structural basis for allosteric modulation of M. tuberculosis proteasome core particle

Authors: Madison Turner, Adwaith B. Uday, Algirdas Velyvis, Enrico Rennella, Natalie Zeytuni & Siavash Vahidi

Journal: Nature Communications

PubMed ID: 40169579

Doi: 10.1038/s41467-025-58430-0

Products & Services: Peptide Synthesis

CodonTransformer: a multispecies codon optimizer using context-aware neural networks

Authors: Adibvafa Fallahpour, Vincent Gureghian, Guillaume J. Filion, Ariel B. Lindner & Amir Pandi

Journal: Nature Communications

PubMed ID: 40180930

Doi: 10.1038/s41467-025-58588-7

Products & Services: Molecular Biology Tools

Structure and inhibition mechanisms of Mycobacterium tuberculosis essential transporter efflux protein A

Authors: Nitesh Kumar Khandelwal, Meghna Gupta, James E Gomez, Sulyman Barkho, Ziqiang Guan, Ashley Y Eng, Tomohiko Kawate, Sree Ganesh Balasubramani, Andrej Sali, Deborah T Hung, Robert M Stroud

Journal: Nature Communications

PubMed ID: 40169593

Doi: 10.1038/s41467-025-58133-6

Products & Services: Mutagenesis Services