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Engineered nucleocytosolic vehicles for loading of programmable editors

Authors: Julian Geilenkeuser, Niklas Armbrust, Emily Steinmaßl, Samuel W Du, Sebastian Schmidt, Eva Maria Hildegard Binder, Yuchun Li, Niklas Wilhelm Warsing, Stephanie Victoria Wendel, Florian von der Linde, Elisa Marie Schiele, Xiya Niu, Luisa Stroppel, Oleksandr Berezin, Tobias Heinrich Santl, Tanja Orschmann, Keith Nelson, Christoph Gruber, Grazyna Palczewska, Carolline Rodrigues Menezes, Eleonora Risaliti, Zachary J Engfer, Naile Koleci, Andrea Schmidts, Arie Geerlof, Krzysztof Palczewski, Gil Gregor Westmeyer, Dong-Jiunn Jeffery Truong

Journal: Cell

PubMed ID: 40209705

Doi: 10.1016/j.cell.2025.03.015

Products & Services: Protein Electrophoresis and Western

Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines

Authors: Paweł S Krawczyk, Michał Mazur, Wiktoria Orzeł, Olga Gewartowska, Sebastian Jeleń, Wiktor Antczak, Karolina Kasztelan, Aleksandra Brouze, Katarzyna Matylla-Kulińska, Natalia Gumińska, Bartosz Tarkowski, Ewelina P Owczarek, Kamila Affek, Paweł Turowski, Agnieszka Tudek, Małgorzata Sroka, Tomasz Śpiewla, Monika Kusio-Kobiałka, Aleksandra Wesołowska, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity, Andrzej Dziembowski, Seweryn Mroczek

Journal: Nature

PubMed ID: 40240603

Doi: 10.1038/s41586-025-08842-1

Products & Services: Molecular Biology Tools

Vesicular and non-vesicular extracellular small RNAs direct gene silencing in a plant-interacting bacterium

Authors: Antinéa Ravet, Jérôme Zervudacki, Meenu Singla-Rastogi, Magali Charvin, Odon Thiebeauld, Alvaro L. Perez-Quintero, Lucas Courgeon, Adrien Candat, Liam Lebeau, Antonio Emidio Fortunato, Venugopal Mendu & Lionel Navarro

Journal: Nature Communications

PubMed ID: 40229238

Doi: 10.1038/s41467-025-57908-1

Products & Services: Gene Synthesis

S-ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide-Induced Depression Via Targeting SIRT2

Authors: Cong Lin, Xiaoxuan Zhou, Mingqi Li, Cong Zhang, Haojiang Zhai, Haohong Li, Hongshuang Wang, Xiaohui Wang

Journal: Advanced Science

PubMed ID: 40171943

Doi: 10.1002/advs.202416481

Products & Services: Protein and Antibody Isolation

Supra-second tracking and live-cell karyotyping reveal principles of mitotic chromosome dynamics

Authors: Rumen Stamatov, Sonya Uzunova, Yoana Kicheva, Maria Karaboeva, Tavian Blagoev, Stoyno Stoynov

Journal: Nature Cell Biology

PubMed ID: 40185948

Doi: 10.1038/s41556-025-01637-6

Products & Services: Custom Vector Construction

Nanoparticle delivery of a prodrug-activating bacterial enzyme leads to anti-tumor responses

Authors: Sebastian G. Huayamares, Liming Lian, Regina Rab, Yuning Hou, Afsane Radmand, Hyejin Kim, Ryan Zenhausern, Bhagelu R. Achyut, Melissa Gilbert Ross, Melissa P. Lokugamage, David Loughrey, Hannah E. Peck, Elisa Schrader Echeverri, Alejandro J. Da Silva Sanchez, Aram Shajii, Andrea Li, Karen E. Tiegreen, Philip J. Santangelo, Eric J. Sorscher & James E. Dahlman

Journal: Nature Communications

PubMed ID: 40221395

Doi: 10.1038/s41467-025-58548-1

Products & Services: Catalog Antibodies

Fibromodulin selectively accelerates myofibroblast apoptosis in cutaneous wounds by enhancing interleukin 1β signaling

Authors: Wenlu Jiang, Xiaoxiao Pang, Pin Ha, Chenshuang Li, Grace Xinlian Chang, Yuxin Zhang, Lawrence A. Bossong, Kang Ting, Chia Soo & Zhong Zheng

Journal: Nature Communications

PubMed ID: 40221432

Doi: 10.1038/s41467-025-58906-z

Products & Services: Mammalian Expression

The bridge-like lipid transport protein VPS13C/PARK23 mediates ER-lysosome contacts following lysosome damage

Authors: Xinbo Wang, Peng Xu, Amanda Bentley-DeSousa, William Hancock-Cerutti, Shujun Cai, Benjamin T. Johnson, Francesca Tonelli, Lin Shao, Gabriel Talaia, Dario R. Alessi, Shawn M. Ferguson & Pietro De Camilli

Journal: Nature Cell Biology

PubMed ID: 40211074

Doi: 10.1038/s41556-025-01653-6

Products & Services: Custom Vector Construction

A predatory gene drive for targeted control of self-transmissible plasmids

Authors: Ryan Tsoi, Hye-In Son, Grayson S Hamrick, Katherine Tang, Jonathan H Bethke, Jia Lu, Rohan Maddamsetti, Lingchong You

Journal: SCIENCE ADVANCES

PubMed ID: 40173243

Doi: 10.1126/sciadv.ads4735

Products & Services: Gene Synthesis

Macrophages direct location-dependent recall of B cell memory to vaccination

Authors: Rama Dhenni, Alexandra Carey Hoppé, Arnold Reynaldi, Wunna Kyaw, Nathalie Tricia Handoko, Abigail K. Grootveld, Yuki Honda Keith, Nayan Deger Bhattacharyya, Holly I. Ahel, Aiden Josiah Telfser, Andrew N. McCorkindale, Seyhan Yazar, Christina H.T. Bui, James T. Smith, Weng Hua Khoo, Mollie Boyd, Solange Obeid, Brad Milner, Mitchell Starr, Fabienne Brilot, Tri Giang Phan

Journal: Molecular Therapy

Doi: 10.1016/j.cell.2025.04.005

Products & Services: Peptide Synthesis