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RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin
Authors: Tal Keren-Kaplan, Amra Sarić, Saikat Ghosh, Chad D Williamson, Rui Jia, Yan Li, Juan S Bonifacino
Journal: Nat Commun
PubMed ID: 35314674
Doi: 10.1038/s41467-022-28952-y
Products & Services: Plasmid DNA Preparation   
Circ_0060531 knockdown ameliorates IL-22-induced keratinocyte damage by binding to miR-330-5p to decrease GAB1 expression
Authors: Quan Shi, Jing Luo, Weiming Chen, Qi He, Jianwen Long, Bo Zhang
Journal: Autoimmunity
PubMed ID: 35293807
Doi: 10.1080/08916934.2022.2037127
Products & Services: Mutant Libraries   
A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants
Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva
Journal: Nat Commun
PubMed ID: 35292635
Doi: 10.1038/s41467-022-28978-2
Products & Services: Codon Optimization   
Age-dependent formation of TMEM106B amyloid filaments in human brains
Authors: Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu, Melissa Huang, Sofia Lövestam, Yang Shi, Yang Yang, Wenjuan Zhang, Abhay Kotecha, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Kathy L Newell, Airi Tarutani, Shigeo Murayama, Masayuki Miyazaki, Yuko Saito, Mari Yoshida, Kazuko Hasegawa, Tammaryn Lashley, Tamas Revesz, Gabor G Kovacs, John van Swieten, Masaki Takao, Masato Hasegawa, Bernardino Ghetti, Maria Grazia Spillantini, Benjamin Ryskeldi-Falcon, Alexey G Murzin, Michel Goedert, Sjors H W Scheres
Journal: Nature
PubMed ID: 35344985
Doi: 10.1038/s41586-022-04650-z
Products & Services: Gene Fragments   
Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone
Authors: Ziling Ye, Yanglei Huang, Bin Shi, Zilei Xiang, Zhu Tian, Man Huang, Liangliang Wu, Zixin Deng, Kun Shen, Tiangang Liu
Journal: Metab Eng
PubMed ID: 35296429
Doi: 10.1016/j.ymben.2022.03.005
Products & Services: Molecular Biology Reagents   
Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH
Authors: Alena Stsiapanava, Chenrui Xu, Shunsuke Nishio, Ling Han, Nao Yamakawa, Marta Carroni, Kathryn Tunyasuvunakool, John Jumper, Daniele de Sanctis, Bin Wu, Luca Jovine
Journal: Nat Struct Mol Biol
PubMed ID: 35273390
Doi: 10.1038/s41594-022-00729-3
Products & Services: Mutant Libraries   
MERS-CoV ORF4b employs an unusual binding mechanism to target IMPα and block innate immunity
Authors: Thilini S Munasinghe, Megan R Edwards, Sofiya Tsimbalyuk, Olivia A Vogel, Kate M Smith, Murray Stewart, Justin K Foster, Loretta A Bosence, David Aragão, Justin A Roby, Christopher F Basler, Jade K Forwood
Journal: Nat Commun
PubMed ID: 35338144
Doi: 10.1038/s41467-022-28851-2
Products & Services: Bacterial Expression   
Co-targeting of BAX and BCL-XL proteins broadly overcomes resistance to apoptosis in cancer
Authors: Andrea Lopez, Denis E Reyna, Nadege Gitego, Felix Kopp, Hua Zhou, Miguel A Miranda-Roman, Lars Ulrik Nordstrøm, Swathi-Rao Narayanagari, Ping Chi, Eduardo Vilar, Aristotelis Tsirigos, Evripidis Gavathiotis
Journal: Nat Commun
PubMed ID: 35256598
Doi: 10.1038/s41467-022-28741-7
Products & Services: Catalog Peptides   
The non-ELR CXC chemokine encoded by human cytomegalovirus UL146 genotype 5 contains a C-terminal β-hairpin and induces neutrophil migration as a selective CXCR2 agonist
Authors: Christian Berg, Michael J Wedemeyer, Motiejus Melynis, Roman R Schlimgen, Lasse H Hansen, Jon Våbenø, Francis C Peterson, Brian F Volkman, Mette M Rosenkilde, Hans R Lüttichau
Journal: PLoS Pathog
PubMed ID: 35271688
Doi: 10.1371/journal.ppat.1010355
Products & Services: Custom Vector Construction   
Diagnostic Host Gene Expression Analysis by Quantitative Reverse Transcription Loop-Mediated Isothermal Amplification to Discriminate between Bacterial and Viral Infections
Authors: Melissa C Remmel, Sabrina M Coyle, Mark W Eshoo, Timothy E Sweeney, David C Rawling
Journal: Clin Chem
PubMed ID: 35134876
Doi: 10.1093/clinchem/hvab275
Products & Services: Mammalian Expression   
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