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A class II MHC-targeted vaccine elicits immunity against SARS-CoV-2 and its variants

Authors: Novalia Pishesha, Thibault J Harmand, Paul W Rothlauf, Patrique Praest, Ryan K Alexander, Renate van den Doel, Mariel J Liebeskind, Maria A Vakaki, Nicholas McCaul, Charlotte Wijne, Elisha Verhaar, William Pinney, Hailey Heston, Louis-Marie Bloyet, Marjorie Cornejo Pontelli, Ma Xenia G Ilagan, Robert Jan Lebbink, William J Buchser, Emmanuel J H J Wiertz, Sean P J Whelan, Hidde L Ploegh

Journal: Proc Natl Acad Sci U S A

PubMed ID: 34654739

Doi: 10.1073/pnas.2116147118

Products & Services: Catalog Peptides cGMP Peptide Synthesis

First cases of SARS-CoV-2 infection in dogs and cats in Thailand

Authors: Waleemas Jairak, Kamonpan Charoenkul, Ekkapat Chamsai, Kitikhun Udom, Supassama Chaiyawong, Napawan Bunpapong, Supanat Boonyapisitsopa, Rachod Tantilertcharoen, Navapon Techakriengkrai, Sirilak Surachetpong, Ratanaporn Tangwangvivat, Kamol Suwannakarn, Alongkorn Amonsin

Journal: Transbound Emerg Dis

PubMed ID: 34739748

Doi: 10.1111/tbed.14383

Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities

Authors: Yaozong Chen, Lulu Sun, Irfan Ullah, Guillaume Beaudoin-Bussières, Sai Priya Anand, Andrew P Hederman, William D Tolbert, Rebekah Sherburn, Dung N Nguyen, Lorie Marchitto, Shilei Ding, Di Wu, Yuhong Luo, Suneetha Gottumukkala, Sean Moran, Priti Kumar, Grzegorz Piszczek, Walther Mothes, Margaret E Ackerman, Andrés Finzi, Pradeep D Uchil, Frank J Gonzalez, Marzena Pazgier

Journal: biorxiv

PubMed ID: 34845451

Doi: 10.1101/2021.11.24.469776

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Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use

Authors: Chunyu Wang, Jiaxu Hong, Zhenlin Yang, Xujiao Zhou, Yuhan Yang, Yu Kong, Binfan Chen, Huifang Wu, Bin-Zhi Qian, Dimiter S Dimitrov, Xingtao Zhou, Yanling Wu, Tianlei Ying

Journal: Small Methods

PubMed ID: 35174992

Doi: 10.1002/smtd.202100966

Products & Services: Mammalian Expression

High-throughput Microwell-seq 2.0 profiles massively multiplexed chemical perturbation

Authors: Haide Chen, Yuan Liao, Guodong Zhang , Zhongyi Sun, Lei Yang, Xing Fang, Huiyu Sun, Lifeng Ma, Yuting Fu, Jingyu Li, Qile Guo, Xiaoping Han, Guoji Guo

Journal: Cell Discov

PubMed ID: 34750394

Doi: 10.1038/s41421-021-00333-7

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Secretion of Gluconic Acid From sp L1 Is Responsible for Solubilization of Aluminum Phosphate

Authors: Xiao Li Li, Xue Qiang Zhao, Xiao Ying Dong, Jian Feng Ma, Ren Fang Shen

Journal: Front Microbiol

PubMed ID: 34867925

Doi: 10.3389/fmicb.2021.784025

Products & Services: Gene Synthesis

Vertical transmission of maternal COVID-19 antibodies after CoronaVac vaccine: A case report

Authors: Bruno Thizon Menegali, Fabiana Schuelter-Trevisol, Alexandre Naime Barbosa, Talita Menegali Izidoro, Otto Henrique May Feurschuette, Chaiana Esmeraldino Mendes Marcon, Daisson José Trevisol

Journal: Rev Soc Bras Med Trop

PubMed ID: 34787263

Doi: 10.1590/0037-8682-0385-2021

Products & Services: Protein and Antibody Reagents

A novel framework integrating AI model and enzymological experiments promotes identification of SARS-CoV-2 3CL protease inhibitors and activity-based probe

Authors: Fan Hu, Lei Wang, Yishen Hu, Dongqi Wang, Weijie Wang, Jianbing Jiang, Nan Li, Peng Yin

Journal: Brief Bioinform

PubMed ID: 34368837

Doi: 10.1093/bib/bbab301

Products & Services: Custom DNA/RNA Oligos

Bioinspired gelatin/bioceramic composites loaded with bone morphogenetic protein-2 (BMP-2) promote osteoporotic bone repair

Authors: M C Echave, I Erezuma, N Golafshan, M Castilho, F B Kadumudi, C Pimenta-Lopes, F Ventura, A Pujol, J J Jimenez, J A Camara, R Hernáez-Moya, L Iturriaga, L Sáenz Del Burgo, I Iloro, M Azkargorta, F Elortza, R Lakshminarayanan, T H Al-Tel, P García-García, R Reyes, A Delgado, C Évora, J L Pedraz, A Dolatshahi-Pirouz, G Orive

Journal: Biomater Adv

PubMed ID: 35513949

Doi: 10.1016/j.msec.2021.112539

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AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway

Authors: Hoi Yin Mak, Qian Ouyang, Sergey Tumanov, Jiesi Xu, Ping Rong, Feitong Dong, Sin Man Lam, Xiaowei Wang, Ivan Lukmantara, Ximing Du, Mingming Gao, Andrew J Brown, Xin Gong, Guanghou Shui, Roland Stocker, Xun Huang, Shuai Chen, Hongyuan Yang

Journal: Nat Commun

PubMed ID: 34824276

Doi: 10.1038/s41467-021-27279-4

Products & Services: Protein and Antibody Isolation