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4D structural biology-quantitative dynamics in the eukaryotic RNA exosome complex

Authors: Jobst Liebau, Daniela Lazzaretti, Torben Fürtges, Anna Bichler, Michael Pilsl, Till Rudack, Remco Sprangers

Journal: Nature Communications

PubMed ID: 40849410

Doi: 10.1038/s41467-025-62982-6.

Products & Services: Codon Optimization

Epsin1 enforces a condensation-dependent checkpoint for ubiquitylated cargo during clathrin-mediated endocytosis

Authors: Susovan Sarkar, Hao-Yang Liu, Feng Yuan, Brandon T Malady, Liping Wang, Eileen M Lafer, Jessica Perez, Jon M Huibregtse, Jeanne C Stachowiak

Journal: Nature Communications

PubMed ID: 40854908

Doi: 10.1038/s41467-025-63238-z.

Products & Services: Custom Vector Construction

Heme allocation in eukaryotic cells relies on mitochondrial heme export through FLVCR1b to cytosolic GAPDH

Authors: Dhanya Thamaraparambil Jayaram, Pranav Sivaram, Pranjal Biswas, Yue Dai, Elizabeth A Sweeny, Dennis J Stuehr

Journal: Nature Communications

PubMed ID: 40858607

Doi: 10.1038/s41467-025-62819-2.

Products & Services: Custom Vector Construction

Nascent liver proteome reveals enzymes and transcription regulators under physiological and alcohol exposure conditions

Authors: Jiayu Gu, Lihui Lao, Linzhen Hu, Jia Zang, Chao Liu, Ruixi Wan, Ling Tang, Ying Yuan, Yulin Chen, Shixian Lin

Journal: Nature Communications

PubMed ID: 40858584

Doi: 10.1038/s41467-025-63212-9.

Products & Services: Protein and Antibody Isolation

Standardizing a Protocol for Streamlined Synthesis and Characterization of Lipid Nanoparticles to Enable Preclinical Research and Education

Authors: Shilpi Agrawal, Abbey L Stokes, Christopher E Nelson

Journal: biorxiv

PubMed ID: 40766677

Doi: 10.1101/2025.07.31.667476

Products & Services: Catalog IVT RNA products

Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Authors: Javier Moral-Sanz; Isabel Fern ndez-Carrasco; Valentina Ramponi; Amanda Garrido; Izhar Karbat; Pablo Cabezas-Sainz; Esperanza Rivera-de-Torre; Osama Elsallabi; Roberto Mart n-Hern ndez; Jos L. L pez-Aceituno; Nathan L. Price; Laura Sanchez; Gonzalo Colmenarejo; lvaro Mart nez-del-Pozo; Irina Vetter; Angel Cogolludo; Francisco Perez-Vizcaino; Jorge Del-Pozo; Eitan Reuveny; Manuel A. Fern ndez-Rojo; Paul D. Robbins; Rafael de Cabo; Manuel Serrano; Maria P. Ikonomopoulou

Journal: Nature Aging

PubMed ID: 41526742

Doi: 10.1038/s43587-025-01030-w

Products & Services: PCR Cloning and Subcloning

Systemic vaccination induces CD8 + T cells and remodels the tumor microenvironment

Authors: Faezzah Baharom; Ramiro A. Ramirez-Valdez; Ahad Khalilnezhad; Shabnam Khalilnezhad; Marlon Dillon; Dalton Hermans; Sloane Fussell; Kennedy K.S. Tobin; Charles-Antoine Dutertre; Geoffrey M. Lynn; S ren M ller; Florent Ginhoux; Andrew S. Ishizuka; Robert A. Seder

Journal: Cell

PubMed ID: 36302380

Doi: 10.1016/j.cell.2022.10.006

Products & Services: Peptide Synthesis

Systemic vaccination induces CD8 + T cells and remodels the tumor microenvironment

Journal: Cell

PubMed ID: 36302380

Doi: 10.1016/j.cell.2022.10.006

Products & Services: Peptide Synthesis

AI-Guided Dual Strategy for Peptide Inhibitor Design Targeting Structural Polymorphs of -Synuclein Fibrils

Authors: Jinfang Duan; Haoyu Zhang; Chuanqi Sun

Journal: Cells

PubMed ID: 41369409

Doi: 10.3390/cells14231921

Products & Services: Peptide Synthesis

Identification of 14-3 3 Proteins as Binding Partners of TRP Channels

Authors: Nicol s Pe a-Vilches; Mariela Gonz lez-Avenda o; Nicole Soto-Garc a; Diego Maureira; Ian Silva; Javiera Avil s; El as Manr quez-Ben tez; Exequiel Medina; Oscar Cerda; Pablo Galaz-Davison; Ariela Vergara-Jaque

Journal: Journal of chemical information and modeling

PubMed ID: 41839059

Doi: 10.1021/acs.jcim.6c00092