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Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

Authors: Zeguang Wu, Jinhong Shi, Qiezhong Lamao, Yuanyuan Qiu, Jinxin Yang, Yang Liu, Feifei Liang, Xue Sun, Wei Tang, Changya Chen, Qingming Yang, Chunmeng Wang, Zhifang Li, Haixia Zhang, Zhonghan Yang, Yunyi Zhang, Yuting Yi, Xufen Zheng, Yu Sun, Kuiying Ma, Lingling Yu, Huihui Yang, Zhaoxuan Wang, Wenjuan Zheng, Ling Yang, Zhixuan Zhang, Yongjian Zhang, Zhiqiang Wu, Yao Wang, Catherine C L Wong, Ming Jin, Pengfei Yuan, Weidong Han, Wensheng Wei

Journal: Cell

PubMed ID: 40845838

Doi: doi.org/10.1016/j.cell.2025.07.046

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A Bivalent mRNA Vaccine Efficiently Prevents Gammaherpesvirus Latent Infection

Authors: Yannan Yin, Jinkai Zang, Huichun Shi, Zhuang Wang, Linlin Kuang, Shuxia Wang, Haikun Wang, Ning Li, Xiaozhen Liang, Zhong Huang

Journal: Vaccines

PubMed ID: 40872916

Products & Services: Gene Synthesis

ANovelDeNovoBiosyntheticPathwayforEfficientSynthesisof6′ SialyllactoseinEscherichiacoli

Authors: Manxiang Zhu,Hongzhi Xia, Xianhao Xu, Yanfeng Liu, Guocheng Du,XuKueqin Lv, Long Liu, Shixiu Cui, Jianghua Li, and Yingyue Li

Journal: Synthetic Biology

Doi: 10.1021/acssynbio.5c00437

Products & Services: Gene Synthesis

Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM

Authors: Jeremy Shek; Chen Sun; Elise M. Wilson; Fatemeh Moadab; Kathryn M. Hastie; Roshan R. Rajamanickam; Patrick J. Penalosa; Stephanie S. Harkins; Diptiben Parekh; Chitra Hariharan; Dawid S. Zyla; Cassandra Yu; Kelly C. L. Shaffer; Victoria I. Lewis; Ruben Diaz Avalos; Tomas Mustelin; Erica Ollmann Saphire

Journal: SCIENCE ADVANCES

PubMed ID: 40864726

Doi: 10.1126/sciadv.ady8168

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Senotoxins target senescence via lipid binding specificity, ion imbalance and lipidome remodeling

Authors: Javier Moral-Sanz; Isabel Fern ndez-Carrasco; Valentina Ramponi; Amanda Garrido; Izhar Karbat; Pablo Cabezas-Sainz; Esperanza Rivera-de-Torre; Osama Elsallabi; Roberto Mart n-Hern ndez; Jos L. L pez-Aceituno; Nathan L. Price; Laura Sanchez; Gonzalo Colmenarejo; lvaro Mart nez-del-Pozo; Irina Vetter; Angel Cogolludo; Francisco Perez-Vizcaino; Jorge Del-Pozo; Eitan Reuveny; Manuel A. Fern ndez-Rojo; Paul D. Robbins; Rafael de Cabo; Manuel Serrano; Maria P. Ikonomopoulou

Journal: Nature Aging

PubMed ID: 41526742

Doi: 10.1038/s43587-025-01030-w

Products & Services: PCR Cloning and Subcloning

DUX4 is a multifunctional factor priming human embryonic genome activation

Authors: Sanna Vuoristo; Shruti Bhagat; Christel Hyd n-Granskog; Masahito Yoshihara; Lisa Gawriyski; Eeva-Mari Jouhilahti; Vipin Ranga; Mahlet Tamirat; Mikko Huhtala; Ida Kirjanov; Sonja Nyk nen; Kaarel Krjut kov; Anastassius Damdimopoulos; Jere Weltner; Kosuke Hashimoto; Ga lle Recher; Sini Ezer; Priit Paluoja; Pauliina Paloviita; Yujiro Takegami; Ai Kanemaru; Karolina Lundin; Tomi T. Airenne; Timo Otonkoski; Juha S. Tapanainen; Hideya Kawaji; Yasuhiro Murakawa; Thomas R. B rglin; Markku Varjosalo; Mark S. Johnson; Timo Tuuri; Shintaro Katayama; Juha Kere

Journal: iScience

PubMed ID: 35402882

Doi: 10.1016/j.isci.2022.104137

Products & Services: Peptide Synthesis

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

14-3-3 interaction with phosphodiesterase 8A sustains PKA signaling and downregulates the MAPK pathway

Authors: Soumita Mukherjee; Somesh Roy; Shruti Mukherjee; Amaravadhi Harikishore; Anirban Bhunia; Atin K. Mandal

Journal: The Journal of Biological Chemistry

PubMed ID: 38325743

Doi: 10.1016/j.jbc.2024.105725

Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin

Authors: Vikram Bhatia; Saeid Maghsoudi; Martha Hinton; Anjali Y. Bhagirath; Nisha Singh; Appalaraju Jaggupilli; Prashen Chelikani; Shyamala Dakshinamurti

Journal: Biology

PubMed ID: 37106773

Doi: 10.3390/biology12040572

Products & Services: Gene Synthesis

Functional Analysis of the Yeast Counterpart to the Human GCN2 p.Glu738_Asp739insArgArg Variant

Authors: Anja H Schiemann, Makhdoom Sarwar, Evelyn Sattlegger

Journal: microPublication biology

PubMed ID: 40880988

Doi: 10.17912/micropub.biology.001767

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