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The CD8α hinge is intrinsically disordered with a dynamic exchange that includes proline cis-trans isomerization

Authors: Xiang Chen, Justin M Mirazee, Katarzyna A Skorupka, Hiroshi Matsuo, Philippe Youkharibache, Naomi Taylor, Kylie J Walters

Journal: J Magn Reson

PubMed ID: 35617919

Doi: 10.1016/j.jmr.2022.107234

Products & Services: Custom Vector Construction

SOLVx therapeutics vaccine - Activate T-cell immunity using broad surveillance epitope strategy against mutant strains SARS-COV2

Authors: Md Shamsuddin Sultan Khan, John A Catanzaro

Journal: Biomed Pharmacother

PubMed ID: 35653885

Doi: 10.1016/j.biopha.2022.113212

Products & Services: Peptide Synthesis

Mitochondrial and glucose metabolic dysfunctions in granulosa cells induce impaired oocytes of polycystic ovary syndrome through Sirtuin 3

Authors: Qing Zhang, Jun Ren, Fangfang Wang, Manman Pan, Long Cui, Mingqian Li, Fan Qu

Journal: Free Radic Biol Med

PubMed ID: 35594990

Doi: 10.1016/j.freeradbiomed.2022.05.010

Products & Services: Protein Electrophoresis and Western

Multiple stem-loop primers induced cascaded loop-mediated isothermal amplification for direct recognition and specific detection of circular RNAs

Authors: Xin Liu, Pengbo Zhang, Kejian Gao, Xiaoyu Wang, Zhengping Li

Journal: Analyst

PubMed ID: 35506753

Doi: 10.1039/d2an00261b

Products & Services: Protein and Antibody Isolation

A Transfected Parasite Line Expressing eGFP Is Able to Complete the Full Life Cycle of the Parasite in Mammalian and Tick Hosts

Authors: Wendell C Johnson, Hala E Hussein, Janaina Capelli-Peixoto, Jacob M Laughery, Naomi S Taus, Carlos E Suarez, Massaro W Ueti

Journal: Pathogens

PubMed ID: 35745477

Doi: 10.3390/pathogens11060623

Products & Services: Plasmid DNA Preparation

Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules

Authors: Janine Dilchert, Martin Hofmann, Felix Unverdorben, Roland Kontermann, Sebastian Bunk

Journal: Antibodies (Basel)

PubMed ID: 35645207

Doi: 10.3390/antib11020034

Products & Services: Custom Vector Construction

Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine

Authors: Shigehiro Tsukahara, Masaki Shiota, Dai Takamatsu, Shohei Nagakawa, Takashi Matsumoto, Ryo Kiyokoba, Mikako Yagi, Daiki Setoyama, Nozomi Noda, Shinya Matsumoto, Tetsutaro Hayashi, Alberto Contreras-Sanz, Peter C Black, Junichi Inokuchi, Kenichi Kohashi, Yoshinao Oda, Takeshi Uchiumi, Masatoshi Eto, Dongchon Kang

Journal: Sci Rep

PubMed ID: 35595780

Doi: 10.1038/s41598-022-12528-3

Products & Services: Mutagenesis Services

LncRNA JPX Promotes Esophageal Squamous Cell Carcinoma Progression by Targeting miR-516b-5p/VEGFA Axis

Authors: Yi He, Rong Hua, Yang Yang, Bin Li, Xufeng Guo, Zhigang Li

Journal: Cancers (Basel)

PubMed ID: 35681693

Doi: 10.3390/cancers14112713

Products & Services: Custom Vector Construction

Atypical B cells up-regulate costimulatory molecules during malaria and secrete antibodies with T follicular helper cell support

Authors: Christine S Hopp, Jeff Skinner, Sarah L Anzick, Christopher M Tipton, Mary E Peterson, Shanping Li, Safiatou Doumbo, Kassoum Kayentao, Aissata Ongoiba, Craig Martens, Boubacar Traore, Peter D Crompton

Journal: Sci Immunol

PubMed ID: 35559666

Doi: 10.1126/sciimmunol.abn1250

Products & Services: Recombinant Proteins

Patients with treated indolent lymphomas immunized with BNT162b2 have reduced anti-spike neutralizing IgG to SARS-CoV-2 variants, but preserved antigen-specific T cell responses

Authors: Brendan Beaton, Sarah C Sasson, Katherine Rankin, Juliette Raedemaeker, Alexander Wong, Priyanka Hastak, Chansavath Phetsouphanh, Andrew Warden, Vera Klemm, C Mee Ling Munier, Alexandra Carey Hoppe, Fiona Tea, Aleha Pillay, Alberto Ospina Stella, Anupriya Aggarwal, Orly Lavee, Ian D Caterson, Stuart Turville, Anthony D Kelleher, Fabienne Brilot, Judith Trotman

Journal: Am J Hematol

PubMed ID: 35607995

Doi: 10.1002/ajh.26619

Products & Services: Catalog Peptides