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WIN site inhibition disrupts a subset of WDR5 function

Authors: Andrew J Siladi, Jing Wang, Andrea C Florian, Lance R Thomas, Joy H Creighton, Brittany K Matlock, David K Flaherty, Shelly L Lorey, Gregory C Howard, Stephen W Fesik, April M Weissmiller, Qi Liu, William P Tansey

Journal: Sci Rep

PubMed ID: 35115608

Doi: 10.1038/s41598-022-05947-9

Products & Services: Gene Synthesis

TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A

Authors: X Rosa Ma, Mercedes Prudencio, Yuka Koike, Sarat C Vatsavayai, Garam Kim, Fred Harbinski, Adam Briner, Caitlin M Rodriguez, Caiwei Guo, Tetsuya Akiyama, H Broder Schmidt, Beryl B Cummings, David W Wyatt, Katherine Kurylo, Georgiana Miller, Shila Mekhoubad, Nathan Sallee, Gemechu Mekonnen, Laura Ganser, Jack D Rubien, Karen Jansen-West, Casey N Cook, Sarah Pickles, Björn Oskarsson, Neill R Graff-Radford, Bradley F Boeve, David S Knopman, Ronald C Petersen, Dennis W Dickson, James Shorter, Sua Myong, Eric M Green, William W Seeley, Leonard Petrucelli, Aaron D Gitler

Journal: Nature

PubMed ID: 35197626

Doi: 10.1038/s41586-022-04424-7

Products & Services: Custom Vector Construction

Non-Invasive Monitoring for Rejection in Kidney Transplant Recipients After SARS-CoV-2 mRNA Vaccination

Authors: Ayman Al Jurdi, Rodrigo B Gassen, Thiago J Borges, Zhabiz Solhjou, Frank E Hullekes, Isadora T Lape, Orhan Efe, Areej Alghamdi, Poojan Patel, John Y Choi, Mostafa T Mohammed, Brigid Bohan, Vikram Pattanayak, Ivy Rosales, Paolo Cravedi, Camille N Kotton, Jamil R Azzi, Leonardo V Riella

Journal: Front Immunol

PubMed ID: 35281011

Doi: 10.3389/fimmu.2022.838985

miR-145-5p inhibits the proliferation of glioma stem cells by targeting translationally controlled tumor protein

Authors: Qiujian Zhang, Zhe Cheng, Lei Shi, Gengsheng Mao

Journal: J Cancer

PubMed ID: 35371310

Doi: 10.7150/jca.65543

Products & Services: Protein and Antibody Isolation

A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination

Authors: Sarah F Andrews, Julie E Raab, Jason Gorman, Rebecca A Gillespie, Crystal S F Cheung, Reda Rawi, Lauren Y Cominsky, Jeffrey C Boyington, Adrian Creanga, Chen-Hsiang Shen, Darcy R Harris, Adam S Olia, Alexandra F Nazzari, Tongqing Zhou, Katherine V Houser, Grace L Chen, John R Mascola, Barney S Graham, Masaru Kanekiyo, Julie E Ledgerwood, Peter D Kwong, Adrian B McDermott

Journal: Nat Med

PubMed ID: 35115707

Doi: 10.1038/s41591-021-01636-8

Products & Services: Recombinant Antibody Expression

In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

Authors: Fang-Yi Su, Qingyang Henry Zhao, Shreyas N Dahotre, Lena Gamboa, Swapnil Subhash Bawage, Aaron D Silva Trenkle, Ali Zamat, Hathaichanok Phuengkham, Rafi Ahmed, Philip J Santangelo, Gabriel A Kwong

Journal: Sci Adv

PubMed ID: 35196075

Doi: 10.1126/sciadv.abm7950

Products & Services: Catalog Antibodies

Selective Detection of Serogroup 1 and 5 with a Digital Photocorrosion Biosensor Using Antimicrobial Peptide-Antibody Sandwich Strategy

Authors: M Amirul Islam, Walid M Hassen, Ishika Ishika, Azam F Tayabali, Jan J Dubowski

Journal: Biosensors (Basel)

PubMed ID: 35200365

Doi: 10.3390/bios12020105

Products & Services: Gene Synthesis

A Triple Gene-Deleted Pseudorabies Virus-Vectored Subunit PCV2b and CSFV Vaccine Protects Pigs against PCV2b Challenge and Induces Serum Neutralizing Antibody Response against CSFV

Authors: Selvaraj Pavulraj, Katrin Pannhorst, Rhett W Stout, Daniel B Paulsen, Mariano Carossino, Denise Meyer, Paul Becher, Shafiqul I Chowdhury

Journal: Vaccines (Basel)

PubMed ID: 35214763

Doi: 10.3390/vaccines10020305

Products & Services: Bacterial Expression

CD19-targeted BiTE expression by an oncolytic vaccinia virus significantly augments therapeutic efficacy against B-cell lymphoma

Authors: Wen Lei, Qian Ye, Yuanyuan Hao, Jie Chen, Yu Huang, Liu Yang, Shibing Wang, Wenbin Qian

Journal: Blood Cancer J

PubMed ID: 35228544

Doi: 10.1038/s41408-022-00634-4

Products & Services: Plasmid DNA Preparation

Characterization of the antibody response to SARS-CoV-2 in a mildly affected pediatric population

Authors: Sonja Kopanja, Pia Gattinger, Klara Schmidthaler, Justyna Sieber, Katarzyna Niepodziana, Thomas Schlederer, Lukas Weseslindtner, Karin Stiasny, Florian Götzinger, Winfried F Pickl, Thomas Frischer, Rudolf Valenta, Zsolt Szépfalusi

Journal: Pediatr Allergy Immunol

PubMed ID: 35212039

Doi: 10.1111/pai.13737

Products & Services: Bacterial Expression