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Single-molecule analysis reveals the mechanism of chromatin ubiquitylation by variant PRC1 complexes

Authors: Alexandra Teslenko , Beat Fierz

Journal: SCIENCE ADVANCES

PubMed ID: 40397729

Doi: 10.1126/sciadv.adt7013

Products & Services: Custom Vector Construction

Stomata-targeted nanocarriers enhance plant defense against pathogen colonization

Authors: Suppanat Puangpathumanond, Heng Li Chee, Cansu Sevencan, Xin Yang, On Sun Lau, Tedrick Thomas Salim Lew

Journal: Nature Communications

PubMed ID: 40410152

Doi: 10.1038/s41467-025-60112-w

Products & Services: Recombinant Proteins

An Engineered PfAgo with Wide Catalytic Temperature Range and Substrate Spectrum

Authors: Longyu Wang, Xiaochen Xie, Fuyong Huang, Qiang Wei, Tianxin Cai, Na Yu, Shi Chen, Fei Wang, Wanping Chen, Chin-Yu Chen, Chunhua Li, Lixin Ma

Journal: Advanced Science

PubMed ID: 40364725

Doi: 10.1002/advs.202416631

Structure and mechanism of human vesicular polyamine transporter

Authors: Yi Guo, Ge Yang, Haijiao Liu, Jin Chai, Jie Chen, John Shanklin, Qun Liu, Bin Liu, Min Lu

Journal: Nature Communications

PubMed ID: 40319071

Doi: 10.1038/s41467-025-59549-w

Products & Services: Gene Synthesis

A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress

Authors: Suman Pokhrel, Gwangbeom Heo, Irimpan Mathews, Shun Yokoi, Tsutomu Matsui, Ayori Mitsutake, Soichi Wakatsuki, Daria Mochly-Rosen

Journal: Nature Communications

PubMed ID: 40328741

Doi: 10.1038/s41467-025-59434-6

Products & Services: Codon Optimization

Structure-based design of potent and selective inhibitors targeting RIPK3 for eliminating on-target toxicity in vitro

Authors: Haixia Su, Guofeng Chen, Hang Xie, Wanchen Li, Muya Xiong, Jian He, Hangchen Hu, Wenfeng Zhao, Qiang Shao, Minjun Li, Qiang Zhao, Yechun Xu

Journal: Nature Communications

PubMed ID: 40341069

Doi: 10.1038/s41467-025-59432-8

Products & Services: Protein Electrophoresis and Western

LKB1 regulates JNK-dependent stress signaling and apoptotic dependency of KRAS-mutant lung cancers

Authors: Chendi Li, Mohammed Usman Syed, Anahita Nimbalkar, Yi Shen, Melissa D Vieira, Cameron Fraser, Zintis Inde, Xingping Qin, Jian Ouyang, Johannes Kreuzer, Sarah E Clark, Grace Kelley, Emily M Hensley, Robert Morris, Raul Lazaro, Brian Belmonte, Audris Oh, Makeba Walcott, Christopher S Nabel, Sean Caenepeel, Anne Y Saiki, Karen Rex, J Russell Lipford, Rebecca S Heist, Jessica J Lin, Wilhelm Haas, Kristopher Sarosiek, Paul E Hughes, Aaron N Hata

Journal: Nature Communications

PubMed ID: 40316540

Doi: 10.1038/s41467-025-58753-y

Products & Services: Gene Synthesis

Single amino acid mutations in histone H3.3 illuminate the functional significance of H3K4 methylation in plants

Authors: Mande Xue, Lijun Ma, Xiaoyi Li, Huairen Zhang, Fengyue Zhao, Qian Liu, Danhua Jiang

Journal: Nature Communications

PubMed ID: 40355503

Doi: 10.1038/s41467-025-59711-4

Fe(III)−H2O2 as an Alternative Oxidant for Catalytic Sulfoxidation in Cytochrome P450 Enzymes: Combined Theoretical and Experimental Evidence

Authors: Musen Li, Langxing Liao, Zhihui Jiang, Zongyu Bao, Shengbiao Ji, Binju Wang

Journal: ACS catalysis

Doi: doi.org/10.1021/acscatal.5c01673

Products & Services: Gene Synthesis Codon Optimization

A general assay platform to study protein pharmacology using ligand-dependent structural dynamics

Authors: Daniel A Ciulla, Patricia K Dranchak, Mahesh Aitha, Renier H P van Neer, Divia Shah, Ravi Tharakan, Kelli M Wilson, Yuhong Wang, John C Braisted, James Inglese

Journal: nature COMMUNICATION

PubMed ID: 40346061

Doi: 10.1038/s41467-025-59658-6

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