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Neoantigen enriched biomimetic nanovaccine for personalized cancer immunotherapy

Authors: Yuwei Li, Maoxin Fang, Haotian Yu, Xianglei Wang, Shiyao Xue, Zeze Jiang, Zixuan Huang, Shaoqin Rong, Xiaoli Wei, Zhigang Lu, Min Luo

Journal: Nature Communications

PubMed ID: 40404668

Doi: 10.1038/s41467-025-59977-8

Products & Services: Peptide Synthesis

T cell memory response to MPXV infection exhibits greater effector function and migratory potential compared to MVA-BN vaccination

Authors: Ji-Li Chen, Beibei Wang, Yongxu Lu, Elie Antoun, Olivia Bird, Philip G Drennan, Zixi Yin, Guihai Liu, Xuan Yao, Maya Pidoux, Adam Bates, Deshni Jayathilaka, Junyuan Wang, Brian Angus, Sally Beer, Alexis Espinosa, J Kenneth Baillie, Malcolm G Semple, ISARIC4C Investigators, Timothy Rostron, Craig Waugh, Paul Sopp, Julian C Knight, James N Fullerton, Mark Coles, Geoffrey L Smith, Alexander J Mentzer, Yanchun Peng, Tao Dong

Journal: Nature Communications

PubMed ID: 40348752

Doi: 10.1038/s41467-025-59370-5

Products & Services: Peptide Synthesis

GzESTY as an optimized cell-based assay for initial steps in GPCR deorphanization

Authors: Luca Franchini , Joseph J Porter , John D Lueck , Cesare Orlandi

Journal: Nature Communications

PubMed ID: 40374633

Doi: 10.1038/s41467-025-59850-8

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Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells

Authors: James R W Conway, Omkar Joshi, Jasmin Kaivola, Gautier Follain, Michalis Gounis, David Kühl, Johanna Ivaska

Journal: Nature Cell Biology

PubMed ID: 40419795

Doi: 10.1038/s41556-025-01663-4

Products & Services: Peptide Synthesis

N 6-methyladenosine modifications stabilize phosphate starvation response–related mRNAs in plant adaptation to nutrient-deficient stress

Authors: Kai Liu, Xiaojia Wang, Jingyi Wang, Shuman Wang, Haiyan Bai, Weiguo Dong, Lulu Qiao, Qiongli Jin, Zhonghui Zhang, Guan-Zheng Luo, Zhiye Wang

Journal: Nature Communications

PubMed ID: 40312414

Doi: 10.1038/s41467-025-59331-y

PP1A Modulates the Efficacy of Lenvatinib Plus ICIs Therapy by Inhibiting Ferroptosis in Hepatocellular Carcinoma

Authors: Jitong Zhou, Meng Gao, Shikun Zhang, Wing-Wa Guo, Wenzhi He, Minghe Zhang, Xi Chen, Cairang Dongzhi, Xiaomian Li, Yufeng Yuan, Weijie Ma

Journal: Advanced Science

PubMed ID: 40344394

Doi: 10.1002/advs.202501730

Products & Services: Protein Electrophoresis and Western

FLT201, a novel liver-directed AAV gene therapy candidate for Gaucher disease type 1

Authors: Fabrizio Comper, Carlos J Miranda, Benjamin Liou, Tihomir Dodev, Jey M Jeyakumar, Miriam Canavese, Clement Cocita, Khashayar Khoshrou, Gustavo Tiscornia, Elisa Chisari, Emmaline Stotter, Erald Shehu, Sudharsan Sridharan, I-Mei Yu, Jalpa Pandya, Jaminder Khinder, Natalie Northcott, Petya Kalcheva, Samantha Correia, Ying Sun, Allison P Dane, Rose Sheridan, Amit C Nathwani, Romuald Corbau

Journal: Molecular Therapy

PubMed ID: 40340248

Doi: 10.1016/j.ymthe.2025.05.003

Products & Services: Gene Synthesis

Mac-1 regulates disease stage-specific immunosuppression via the nitric oxide pathway in autoimmune disease

Authors: Wei Wang , Chunzhang Cao , Vishnuprabu Durairaj Pandian , Haofeng Ye , Hongxia Chen , Li Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 40344054

Doi: 10.1126/sciadv.ads3728

Products & Services: Catalog Peptides

Heterologous synthesis of a simplified nitrogenase analog in Escherichia coli

Authors: Yiling A Liu, Chi Chung Lee, Kamil Górecki, Martin T Stiebritz, Calder Duffin, Joseph B Solomon, Markus W Ribbe, Yilin Hu

Journal: SCIENCE ADVANCES

PubMed ID: 40315313

Doi: 10.1126/sciadv.adw6785

Products & Services: Codon Optimization

PKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma

Authors: Binfeng Liu, Wei Li, Wenchao Zhang, Chengyao Feng, Lu Wan, Shasha He, Ruiling Xu, Zheng Fu, Zhongyue Liu, Haodong Xu, Xin Jin, Chao Tu, Zhihong Li

Journal: Signal Transduct Target Ther

PubMed ID: 40393983

Doi: 10.1038/s41392-025-02250-7

Products & Services: Catalog Antibodies